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HMG2 / HMGB2

high mobility group box 2

HMG2 / HMGB2 is a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.

Gene Name: high mobility group box 2
Synonyms: HMGB2, HMG-2, High mobility group box 2, High-mobility group box 2, HMG2, High mobility group protein 2, High mobility group protein B2
Target Sequences: NM_002129 NP_002120.1 P26583

Publications (1)

1
HIV antiretroviral therapy drugs induce premature senescence and altered physiology in HUVECs. Justin Cohen, Luca D'Agostino, Ferit Tuzer, Claudio Torres. Mechanisms of ageing and development. 2018 October;175:74-82. [Full Text Article] [PubMed:30055190] [PMC:PMC6133242] Related Antibodies: LS-B4355.

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Products
Antibodies (49)
Primary (49)
HMG2 / HMGB2 (49)
Human (49)
Mouse (20)
Rat (18)
Bat (9)
Bovine (10)
Chicken (3)
Chimpanzee (9)
Dog (9)
Gibbon (9)
Guinea pig (6)
Horse (9)
Monkey (9)
Pig (9)
Rabbit (9)
IHC (18)
IHC-P (13)
WB (45)
ELISA (12)
ICC (1)
IF (6)
IP (1)
Peptide-ELISA (2)
rabbit (45)
mouse (4)
Product Group
IHCPlus (3)
IgG (24)
IgG1 (1)
IgG1,k (1)
IgG2a,k (2)
monoclonal mc (4)
polyclonal pc (45)
3C7 (1)
3D2 (1)
3E5 (1)
FBH7 (1)
APC (1)
APC Conjugated (2)
Biotin Conjugated (6)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (6)
HRP Conjugated (6)
PE Conjugated (2)
Unconjugated (25)
aa2-187 (8)
C-Terminus (4)
aa107-156 (4)
aa72-121 (4)
100-180 aa, Internal (1)
Internal (1)
Lys165 (1)
aa131-180 (1)
aa92-118 (1)
No (48)
Yes (1)
HMG2 / HMGB2 Antibody - Anti-HMGB2 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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HMG2 / HMGB2 Mouse anti-Human Monoclonal (3D2) Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$440
HMG2 / HMGB2 Antibody - HMGB2 antibody ARP31939_P050-NP_002120-HMGB2 (high-mobility group box 2) Antibody IHC of formalin-fixed, paraffin-embedded human Lung. Positive label: Alveolar Cells indicated with arrows. Antibody concentration 4-8 ug/ml. Magnification 400X.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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HMG2 / HMGB2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$424
HMG2 / HMGB2 Antibody - HMGB2 antibody ARP31939_P050-NP_002120-HMGB2 (high-mobility group box 2) Antibody IHC of formalin-fixed, paraffin-embedded human Lung. Positive label: Alveolar Cells indicated with arrows. Antibody concentration 4-8 ug/ml. Magnification 400X.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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HMG2 / HMGB2 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
HMG2 / HMGB2 Antibody - HMGB2 antibody ARP31939_P050-NP_002120-HMGB2 (high-mobility group box 2) Antibody IHC of formalin-fixed, paraffin-embedded human Lung. Positive label: Alveolar Cells indicated with arrows. Antibody concentration 4-8 ug/ml. Magnification 400X.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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HMG2 / HMGB2 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
HMG2 / HMGB2 Antibody - HMGB2 antibody ARP31939_P050-NP_002120-HMGB2 (high-mobility group box 2) Antibody IHC of formalin-fixed, paraffin-embedded human Lung. Positive label: Alveolar Cells indicated with arrows. Antibody concentration 4-8 ug/ml. Magnification 400X.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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HMG2 / HMGB2 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
HMG2 / HMGB2 Antibody - Anti-HMGB2 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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HMG2 / HMGB2 Mouse anti-Human Monoclonal (3C7) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
HMG2 / HMGB2 Antibody - Immunofluorescence of monoclonal antibody to HMGB2 on HeLa cell (antibody concentration 10 ug/ml).
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HMG2 / HMGB2 Mouse anti-Human Monoclonal (3E5) Antibody
Human
ELISA, IF, WB
Unconjugated
100 µg/$423
HMG2 / HMGB2 Antibody - Immunohistochemical analysis of HMGB2 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected with HRP and DAB as chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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HMG2 / HMGB2 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Bovine, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
HMG2 / HMGB2 Antibody - HMGB2 Antibody western blot of HL-60,K562,H-4-II-E cell line lysates (35 ug/lane). The HMGB2 antibody detected the HMGB2 protein (arrow).
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HMG2 / HMGB2 Rabbit anti-Human Polyclonal (aa92-118) Antibody
Human
WB
Unconjugated
400 µl/$393
HMG2 / HMGB2 Antibody - Western blot of HMG-2 antibody
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HMG2 / HMGB2 Rabbit anti-Human Polyclonal (100-180 aa, Internal) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
HMG2 / HMGB2 Antibody - Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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HMG2 / HMGB2 Rabbit anti-Human Polyclonal (aa107-156) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
HMG2 / HMGB2 Antibody - Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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HMG2 / HMGB2 Rabbit anti-Human Polyclonal (aa107-156) (HRP) Antibody
Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
HMG2 / HMGB2 Antibody - Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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HMG2 / HMGB2 Rabbit anti-Human Polyclonal (aa107-156) (Biotin) Antibody
Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
HMG2 / HMGB2 Antibody - Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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HMG2 / HMGB2 Rabbit anti-Human Polyclonal (aa107-156) (FITC) Antibody
Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
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HMG2 / HMGB2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IP, WB
Unconjugated
100 µg/$331
HMG2 / HMGB2 Antibody - HMGB2 was detected in paraffin-embedded sections of mouse intestine tissues using rabbit anti- HMGB2 Antigen Affinity purified polyclonal antibody
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HMG2 / HMGB2 Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
HMG2 / HMGB2 Antibody - Immunohistochemistry of paraffin-embedded human brain tissue using HMGB2 Antibody at dilution of 1:100
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HMG2 / HMGB2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC
Unconjugated
50 µg/$294; 100 µg/$360
HMG2 / HMGB2 Antibody - Staining COLO205 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
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HMG2 / HMGB2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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HMG2 / HMGB2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
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HMG2 / HMGB2 Rabbit anti-Human Polyclonal (Lys165) Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µl/$321; 100 µl/$403
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HMG2 / HMGB2 Rabbit anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
20 µl/$250; 60 µl/$286; 120 µl/$349; 200 µl/$439
HMG2 / HMGB2 Antibody - IHC testing of FFPE human intestinal cancer tissue with HMGB2 antibody at 1ug/ml. HIER: steam in pH6 citrate buffer and allow to cool prior to staining.
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HMG2 / HMGB2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC-P, WB
Unconjugated
100 µg/$575
HMG2 / HMGB2 Antibody - Western blot analysis of HeLa and 231 cell, using HMGB2 Polyclonal Antibody at dilution of 1:2000.
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HMG2 / HMGB2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
HMG2 / HMGB2 Antibody - Western blot analysis of extracts from COLO205 cells, using HMGB2 antibody.
Select
HMG2 / HMGB2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
HMG2 / HMGB2 Antibody - Western blot analysis of lysates from COLO205 cells, using HMGB2 Antibody. The lane on the right is blocked with the synthesized peptide.
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HMG2 / HMGB2 Rabbit anti-Human Polyclonal (aa131-180) Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).