HLA-A

Major Histocompatibility Complex, Class I, A Heavy Chain

HLA-A belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-A alleles have been described.

☰ Filters

Products

Proteins (7)

Type

Over-Expression Lysate (3)

Recombinant (4)

Target

HLA-A (7)

Publications

No (7)

Tag

6His, N-terminus (1)

GST (1)

His, N-Terminal (2)

Myc-DDK (Flag) (3)

Species

Human (6)

Source

293T Cells (1)

E. coli (2)

HEK 293 Cells (3)

Wheat Germ Extract (1)

Purification

Purified (3)

Select

Human HLA-A Protein (Recombinant 6His, N-terminus) - LS-G137222

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

36.7 kDa

Price:

1 mg/$1,679; 100 µg/$598; 20 µg/$405

Select

Human HLA-A Protein (Recombinant GST) (Full Length) - LS-G28832

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

63.36 kDa

Price:

2 µg/$439

Select

Human HLA-A Protein (Over-Expression Lysate His, N-Terminal) (Gly25-Ile308) - LS-G96949

Source:

HEK 293 Cells

Tag:

His, N-Terminal

Molecular Weight:

~33 kDa

Price:

100 µg/$298

Select

Human HLA-A Protein (Recombinant His, N-Terminal) (Gly25-Ile308) - LS-G96947

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

37 kDa

Price:

10 µg/$265; 200 µg/$484; 50 µg/$315

Select

Human HLA-A Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G68034

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

38.5 kDa

Price:

20 µg/$1,107

Select

Human HLA-A Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G81268

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

40.85 kDa

Price:

20 µg/$150

Select

HLA-A Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99654

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

40.85 kDa

Price:

100 µg/$494

Viewing 1-7 of 7 product results

(0) Selected Add Selected To Cart Compare Selected Email Selected Clear Selected Top Of Search

---

Filtered By:

Products: Proteins

Clear Filters

If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.