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GSTM1

glutathione S-transferase mu 1

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene.

Gene Name: glutathione S-transferase mu 1
Synonyms: GSTM1, Glutathione S-aryltransferase, GSTM1-1, GSTM1a-1a, GSTM1b-1b, Glutathione S-alkyltransferase, GTH4, GST class-mu 1, GST1, GTM1, H-B, HB subunit 4, MU-1, Glutathione S-transferase M1, Glutathione S-transferase mu 1, GST HB subunit 4
Target Sequences: NM_000561 NP_000552.2 P09488

Publications (2)

1
5,6-Dihydrocyclopenta[c][1,2]-dithiole-3(4H)-thione is a promising cancer chemopreventive agent in the urinary bladder. Paonessa JD, Munday CM, Mhawech-Fauceglia P, Munday R, Zhang Y. Chemico-biological interactions. 2009 180:119-26. (IHC-P; Rat) [Full Text Article] [PubMed:19121294] [PMC:PMC2684030] Related Antibodies: LS-B963.
2
Multimeric structures of HLA-G isoforms function through differential binding to LILRB receptors. Sirinyan M, Sennlaub F, Dorfman A, Sapieha P, Gobeil F, Hardy P, Lachapelle P, Chemtob S. Cellular and molecular life sciences : CMLS. 2012 (Flo; Human) [PubMed:22802125]

☰ Filters
Antibodies (74)
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GSTM1 (98)
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GSTM1 Antibody - Anti-GSTM1 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GSTM1 Rabbit anti-Human Polyclonal (aa31-80) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
GSTM1 Antibody - Anti-GSTM1 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GSTM1 Rabbit anti-Human Polyclonal (aa31-80) (HRP) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Horse, Bat, Gibbon, Orangutan, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
GSTM1 Antibody - Anti-GSTM1 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GSTM1 Rabbit anti-Human Polyclonal (aa31-80) (Biotin) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Horse, Bat, Gibbon, Orangutan, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
GSTM1 Antibody - Anti-GSTM1 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GSTM1 Rabbit anti-Human Polyclonal (aa31-80) (FITC) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Horse, Bat, Gibbon, Orangutan, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
GSTM1 Antibody - Anti-GSTM1 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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GSTM1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
GSTM1 Antibody - IHC of paraffin-embedded rectum cancer tissues using GSTM1 mouse monoclonal antibody with DAB staining.
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GSTM1 Mouse anti-Human Monoclonal (1H4A4) Antibody
Human
ELISA, Flo, IHC, IHC-P, WB
Unconjugated
100 µl/$459
GSTM1 Antibody - Western Blot of Mouse anti-GSTM1 Monoclonal Antibody. Lane 1: rGSTM1 protein. Lane 2: GST. Load: 50 ng per lane. Primary antibody: Mouse anti-GSTM1 Monoclonal Antibody at 1:1,000 overnight at 4°C. Secondary antibody: Peroxidase conjugated Rb-a-Ms IgG at 1:40,000 for 30 min at RT. Block: MB-070 for 30 min at RT. Predicted/Observed size: 27 kDa, 27 kDa for GSTM1.
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GSTM1 Mouse anti-Mouse Monoclonal (1H7.D8.G5) Antibody
Mouse, Human
ELISA, IHC, IP, WB
Unconjugated
100 µg/$574
GSTM1 Antibody - IHC of paraffin-embedded stomach cancer tissues using GSTM1 mouse monoclonal antibody with DAB staining.
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GSTM1 Mouse anti-Human Monoclonal (1H4F2) Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
100 µl/$459
GSTM1 Antibody - IHC analysis of GSTM1 using anti-GSTM1 Antibody. GSTM1 was detected in paraffin-embedded section of rat liver tissue . Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 2µg/ml mouse anti-GSTM1 Antibody overnight at 4°C. Biotinylated goat anti-mouse IgG was used as secondary antibody and incubated for 30 minutes at 37°C. The tissue section was developed using Strepavidin-Biotin-Complex (SABC) with DAB as the chromogen.
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GSTM1 Mouse anti-Human Monoclonal Antibody
Mouse, Rat, Human
Flo, ICC, IHC-Fr, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
GSTM1 Antibody - GSTM1 Antibody in Immunohistochemistry (IHC)
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GSTM1 Mouse anti-Human Monoclonal (1H4F2) Antibody
Rat, Human
Flo, IHC, WB
Unconjugated
100 µl/$503
GSTM1 Antibody - Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with GSTM1 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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GSTM1 Rabbit anti-Human Polyclonal (aa184-211) Antibody
Mouse, Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
GSTM1 Antibody - Anti-GSTM1 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GSTM1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
GSTM1 Antibody - Anti-GSTM1 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GSTM1 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody
Bovine, Human, Gibbon
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
GSTM1 Antibody - Anti-GSTM1 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GSTM1 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Bovine, Human, Gibbon
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
GSTM1 Antibody - Anti-GSTM1 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GSTM1 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Bovine, Human, Gibbon
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
GSTM1 Antibody - Immunohistochemistry of paraffin-embedded human liver tissue using GSTM1 Antibody at dilution of 1:100
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GSTM1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC
Unconjugated
50 µg/$294; 100 µg/$360
GSTM1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
6.25 - 400 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$715
GSTM1 Protein - Recombinant Glutathione S Transferase Mu 1 By SDS-PAGE
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E. coli
His, N-Terminal
27.1 kDa
10 µg/$267; 50 µg/$352; 100 µg/$562; 200 µg/$702; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900
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GSTM1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$341
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GSTM1 Mouse anti-Human Monoclonal Antibody
Human
ELISA, WB
Unconjugated
100 µl/$413
GSTM1 Antibody - Immunohistochemistry of paraffin-embedded Human lung cancer tissue  using GSTM2 Polyclonal Antibody at dilution of 1:50(×200)
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GSTM1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
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GSTM1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µl/$801
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GSTM1 Rabbit anti-Human Polyclonal (aa184-211) Antibody
Mouse, Human
ELISA, WB
Unconjugated
200 µl/$734
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GSTM1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
GSTM1 Antibody - Western blot analysis of lysates from HepG2 cells, using GSTM1 antibody.
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GSTM1 Rabbit anti-Human Polyclonal (aa101-150) Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
Viewing 1-25 of 98 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).