GRN / Granulin

granulin

Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88 kDa precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis.

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Products

Antibodies (95)

ELISA Kits (37)

Proteins (17)

Type

Custom (3)

Development Kit (2)

Over-Expression Lysate (2)

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Recombinant (15)

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Target

GRN / Granulin (149)

Reactivity

Human (93)

Mouse (37)

Rat (8)

Chicken (1)

Chimpanzee (3)

Gibbon (3)

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Hamster (1)

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Host

rabbit (72)

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goat (2)

guinea pig (1)

rat (3)

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IgG1 (11)

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IgG2a,k (1)

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Epitope

aa327-593 (12)

aa361-585 (10)

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Internal (4)

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aa20-310 (1)

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No (148)

Yes (1)

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Breast Milk (1)

Cell Culture Supernatants (13)

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IHC-plus™ GRN / Granulin Antibody (C-Terminus) LS-B3158

(4.0) Rating

Antibody:

GRN / Granulin Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

50 µg/$485

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GRN / Granulin Antibody (aa248-259) LS-C154960

(4.0) Rating

(1) Publication(s)

Antibody:

GRN / Granulin Goat anti-Human Polyclonal (aa248-259) Antibody

Reactivity:

Mouse, Rat, Hamster, Human, Monkey

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µg/$503

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GRN / Granulin Antibody LS-C75078

Antibody:

GRN / Granulin Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, IP, WB

Format:

Unconjugated

Price:

100 µg/$962

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Mouse GRN / Granulin (Sandwich ELISA) ELISA Kit - LS-F284

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

20.58 - 15000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$534

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Rabbit GRN / Granulin (Sandwich ELISA) ELISA Kit - LS-F44584

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rabbit

Range:

3.13 - 200 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

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GRN / Granulin Antibody (aa257-269) LS-C112750

Antibody:

GRN / Granulin Goat anti-Human Polyclonal (aa257-269) Antibody

Reactivity:

Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µg/$503

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IHC-plus™ GRN / Granulin Antibody LS-B12886

(4.0) Rating

Antibody:

GRN / Granulin Guinea pig anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

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Monkey GRN / Granulin (Sandwich ELISA) ELISA Kit - LS-F44586

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

1.56 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$728

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GRN / Granulin Antibody (aa327-593, clone OTI1F9) LS-C340249

Antibody:

GRN / Granulin Mouse anti-Human Monoclonal (aa327-593) (OTI1F9) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$434

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GRN / Granulin Antibody LS-C665975

Antibody:

GRN / Granulin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IP, WB

Format:

Unconjugated

Price:

100 µg/$331

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GRN / Granulin Antibody (aa361-585) LS-C294322

Antibody:

GRN / Granulin Rabbit anti-Human Polyclonal (aa361-585) Antibody

Reactivity:

Human

Applications:

ICC, IP, WB

Format:

Unconjugated

Price:

100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225

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GRN / Granulin Antibody LS-C806947

Antibody:

GRN / Granulin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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Human GRN / Granulin (Sandwich ELISA) ELISA Kit - LS-F26962

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

50 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$805

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Human GRN / Granulin Protein (Recombinant His-S) (aa21-120) - LS-G14970

Source:

E. coli

Tag:

His-S

Molecular Weight:

16.1 kDa

Price:

10 µg/$259; 50 µg/$331; 100 µg/$482; 200 µg/$602; 1 mg/$1,553; 500 µg/$1,156; 5 mg/$2,481; 2 mg/$1,723

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GRN / Granulin Antibody (aa327-593, clone OTI2F4) LS-C340286

Antibody:

GRN / Granulin Mouse anti-Human Monoclonal (aa327-593) (OTI2F4) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$434

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GRN / Granulin Antibody (clone 1F5) LS-C197353

Antibody:

GRN / Granulin Mouse anti-Human Monoclonal (1F5) Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

100 µg/$423

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GRN / Granulin Antibody LS-C486786

Antibody:

GRN / Granulin Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, ICC, IF

Format:

Unconjugated

Price:

20 µl/$256; 100 µl/$412

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GRN / Granulin Antibody (aa327-593, clone OTI2D1) LS-C794038

Antibody:

GRN / Granulin Mouse anti-Human Monoclonal (aa327-593) (OTI2D1) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µl/$434

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GRN / Granulin Antibody (aa327-593, clone OTI4B9) LS-C794035

Antibody:

GRN / Granulin Mouse anti-Human Monoclonal (aa327-593) (OTI4B9) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µl/$434

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GRN / Granulin Antibody (aa327-593, clone OTI3B3) LS-C794037

Antibody:

GRN / Granulin Mouse anti-Human Monoclonal (aa327-593) (OTI3B3) Antibody

Reactivity:

Human

Applications:

IHC

Format:

Unconjugated

Price:

100 µl/$434

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GRN / Granulin Antibody LS-C747542

Antibody:

GRN / Granulin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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GRN / Granulin Antibody LS-C144115

Antibody:

GRN / Granulin Rat anti-Mouse Monoclonal Antibody

Reactivity:

Mouse

Applications:

ELISA

Format:

Unconjugated

Price:

500 µg/$1,089

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GRN / Granulin Antibody (clone 019, Preservative Free) LS-C819383

Antibody:

GRN / Granulin Rabbit anti-Mouse Monoclonal (Preservative Free) (019) Antibody

Reactivity:

Mouse

Applications:

ELISA

Format:

Unconjugated, Preservative Free

Price:

20 µl/$271; 100 µl/$412

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GRN / Granulin Antibody (aa31-269) LS-C294321

Antibody:

GRN / Granulin Rabbit anti-Mouse Polyclonal (aa31-269) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261

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GRN / Granulin Antibody (aa21-120) LS-B14618

Antibody:

GRN / Granulin Rabbit anti-Human Polyclonal (aa21-120) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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