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GRM5 / MGLUR5

glutamate receptor, metabotropic 5

Group I of the Metabotropic Glutamate Receptors includes GRM1 and GRM5, receptors that have been shown to activate phospholipase C. Alternative splice variants of GRM5 have been described, but their full-length nature has not been determined. Inflammation results in the activation of mGluR1 and mGluR5 in dorsal horn neurons of the spinal cord, leading to extracellular signal-regulated kinase (ERK) activation, which is required for nociceptive plasticity and enhanced pain. GRM5 is involved in inflammatory mechanical hyperalgesia and potentially in schizophrenia. Summary of expresson: GRM5 has been reported to be expressed in various regions of the brain as well as in the spinal cord and dorsal root ganglia.

Gene Name: glutamate receptor, metabotropic 5
Family/Subfamily: GPCR , Metabotropic glutamate
Synonyms: GRM5, GPRC1E, MGLUR5, Mglur5b, MGlu5
Target Sequences: NM_000842 NP_000833.1 P41594

☰ Filters
Antibodies (31)
ELISA Kits (4)
Proteins (3)
Over-Expression Lysate (2)
Primary (31)
Recombinant (1)
Sandwich (4)
GRM5 / MGLUR5 (38)
Human (30)
Mouse (24)
Rat (17)
Bat (1)
Bovine (1)
Chicken (2)
Dog (2)
Hamster (1)
Horse (1)
Monkey (3)
Pig (2)
Rabbit (1)
IHC (10)
IHC-P (4)
WB (29)
Flo (1)
ELISA (13)
ICC (3)
IF (8)
Peptide-ELISA (3)
rabbit (25)
mouse (6)
Product Group
GPCR Database Antibodies (2)
IHCPlus (1)
PathPlus Neuro (1)
IgG (17)
IgG1 (4)
IgG2a (1)
IgG2a,k (1)
monoclonal mc (6)
polyclonal pc (25)
1A11D10 (1)
1B3 (1)
8H5D5 (1)
S75-3 (1)
S75-33 (1)
96-Well Strip Plate (4)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
PE Conjugated (1)
Preservative Free (1)
Unconjugated (26)
aa1020-1050 (7)
N-Terminus (3)
C-Terminus (2)
40-120 aa, N-terminal (1)
Lys56 (1)
aa19-509 (1)
aa21-70 (1)
aa7-56 (1)
No (38)
Plasma (4)
Serum (4)
Tissue Homogenates (1)
GST, N-terminus (1)
Myc-DDK (Flag) (2)
Human (2)
293T Cells (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
GRM5 / MGLUR5 Antibody - Anti-GRM5 / MGLUR5 antibody IHC of human colon, myenteric plexus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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GRM5 / MGLUR5 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Chicken, Bovine, Rat, Hamster, Pig, Horse, Bat, Rabbit, Mouse, Dog, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$440
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GRM5 / MGLUR5 Mouse anti-Human Monoclonal (aa19-509) Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µg/$872
GRM5 / MGLUR5 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
GRM5 / MGLUR5 Antibody - Anti-GRM5 / MGLUR5 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Neuroscience
Fast Shipping
GRM5 / MGLUR5 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human, Monkey
IHC, IHC-P, WB
Unconjugated
50 µg/$460
GRM5 / MGLUR5 Antibody - Immunofluorescence analysis of Hela cells using GRM5 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher
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GRM5 / MGLUR5 Mouse anti-Human Monoclonal (1A11D10) Antibody
Human
ELISA, ICC, IHC, WB
Unconjugated
100 µl/$459
GRM5 / MGLUR5 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
GRM5 / MGLUR5 Antibody - Immunohistochemical analysis of mGLUR5 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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GRM5 / MGLUR5 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Dog, Rat, Pig, Human, Monkey
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$299
GRM5 / MGLUR5 Antibody - Western blot of mGluR5 antibody
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GRM5 / MGLUR5 Rabbit anti-Human Polyclonal (40-120 aa, N-terminal) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
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GRM5 / MGLUR5 Rabbit anti-Rat Polyclonal Antibody
Mouse, Rat
ICC, IF, IHC, WB
Unconjugated
50 µg/$1,027
GRM5 / MGLUR5 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
GRM5 / MGLUR5 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
GRM5 / MGLUR5 Antibody - Western blot of mGluR5 (K56) pAb in extracts from A549 cells.
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GRM5 / MGLUR5 Rabbit anti-Human Polyclonal (Lys56) Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
50 µl/$321; 100 µl/$403
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GRM5 / MGLUR5 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$440; 100 µg/$480
GRM5 / MGLUR5 Antibody - Peptide - + Immunofluorescence analysis of LOVO cells, using GRM5 antibody.
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GRM5 / MGLUR5 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, WB
Unconjugated
100 µg/$357
GRM5 / MGLUR5 Antibody - Immunofluorescence analysis of LOVO cells, using GRM5 Antibody. The picture on the right is blocked with the synthesized peptide.
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GRM5 / MGLUR5 Rabbit anti-Human Polyclonal (aa21-70) Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
GRM5 / MGLUR5 Antibody - Western blot analysis using GRM5 mAb against HEK293 (1) and GRM5 (AA: extra 458-580)-hIgGFc transfected HEK293 (2) cell lysate.
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GRM5 / MGLUR5 Mouse anti-Human Monoclonal (8H5D5) Antibody
Human
ELISA, WB
Unconjugated
100 µl/$459
GRM5 / MGLUR5 Antibody - Staining A431 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% saponin prior to blocking in 10% serum for 45 min at 37°C. The primary antibody was diluted 1:200 and incubated with the sample for 1 hour at 37°C. A Alexa Fluor 594 conjugated goat polyclonal to rabbit IgG (H+L), diluted 1/600 was used as secondary antibody.
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GRM5 / MGLUR5 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
GRM5 / MGLUR5 Antibody - Western blot of GRM5 expression in HT-29 cells
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GRM5 / MGLUR5 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, WB
Unconjugated
50 µg/$305; 100 µg/$357
GRM5 / MGLUR5 Antibody - Detection limit for recombinant GST tagged GRM5 is approximately 0.03 ng/ml as a capture antibody.
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GRM5 / MGLUR5 Mouse anti-Human Monoclonal (1B3) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
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GRM5 / MGLUR5 Rabbit anti-Human Polyclonal (aa1020-1050) Antibody
Mouse, Human
ELISA, WB
Unconjugated
200 µl/$734
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GRM5 / MGLUR5 Rabbit anti-Human Polyclonal (aa1020-1050) (FITC) Antibody
Mouse, Human
ELISA, WB
FITC Conjugated
200 µl/$952
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GRM5 / MGLUR5 Rabbit anti-Human Polyclonal (aa1020-1050) (APC) Antibody
Mouse, Human
ELISA, WB
APC Conjugated
200 µl/$952
GRM5 / MGLUR5 Antibody - Immunoblot on  rat brain membranes.
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GRM5 / MGLUR5 Mouse anti-Rat Monoclonal (S75-33) Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
100 µg/$537
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GRM5 / MGLUR5 Rabbit anti-Rat Polyclonal Antibody
Rat
IHC, WB
Unconjugated
100 µl/$558
GRM5 / MGLUR5 Antibody - Western blot analysis of the lysates from HeLa cells using GRM5 antibody.
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GRM5 / MGLUR5 Rabbit anti-Human Polyclonal (aa7-56) Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
Viewing 1-25 of 38 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).