GRB2

growth factor receptor-bound protein 2

Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway.Isoform 2 does not bind to phosphorylated epidermal growth factor receptor (EGFR) but inhibits EGF-induced transactivation of a RAS-responsive element. Isoform 2 acts as a dominant negative protein over GRB2 and by suppressing proliferative signals, may trigger active programmed cell death.

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Products

Antibodies (54)

Proteins (18)

ELISA Kits (13)

Type

Over-Expression Cell Culture Supernatant (1)

Over-Expression Lysate (5)

Primary (54)

Recombinant (12)

Sandwich (12)

Sandwich CLIA (1)

Target

GRB2 (85)

Reactivity

Human (59)

Mouse (29)

Rat (24)

Bat (4)

Bovine (11)

Chicken (4)

Chimpanzee (3)

Dog (4)

Gibbon (3)

Guinea pig (4)

Hamster (10)

Horse (4)

Monkey (7)

Orangutan (3)

Pig (5)

Porcine (1)

Rabbit (5)

Sheep (1)

Xenopus (3)

Zebrafish (4)

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Application

IHC (16)

IHC-P (6)

WB (50)

ELISA (17)

IF (4)

Immuno-MRM (1)

Peptide-ELISA (6)

Host

rabbit (39)

mouse (12)

goat (3)

Product Group

IHCPlus (4)

Isotype

IgG (22)

IgG1 (1)

IgG1,k (8)

IgM,k (1)

Clonality

monoclonal mc (11)

polyclonal pc (42)

recombinant monoclonal rmc (1)

Clone

3F2 (1)

4C6-H6 (1)

Polyclonal (1)

SAIC-19D-1F4 (1)

Format

12 x 8-Well Microstrips (3)

96-Well Microplate (1)

96-Well Strip Plate (9)

APC (1)

APC Conjugated (3)

Azide-free (1)

Biotin Conjugated (7)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (5)

HRP Conjugated (5)

PE Conjugated (3)

Preservative Free (2)

Unconjugated (29)

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Epitope

aa1-217 (9)

Tyr209 (6)

N-Terminus (4)

110-190 aa, Internal (1)

Arg178 (1)

C-Terminus (1)

Internal (1)

aa129-178 (1)

aa141-190 (1)

aa206-217 (1)

aa89-118 (1)

pSer159 (1)

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Publications

No (85)

Sample Type

Plasma (6)

Serum (6)

Tissue Homogenates (2)

Tag

6His, C-terminus (2)

6His, N-terminus (5)

GST (1)

GST, N-terminus (1)

His (2)

His, N-Terminal (1)

His-T7 (1)

Myc-DDK (Flag) (5)

Species

Human (16)

Source

293F Cells (2)

293T Cells (2)

E. coli (6)

HEK 293 Cells (6)

Wheat Germ Extract (2)

Purification

Purified (4)

Low Endotoxin Level

Low endotoxin level (2)

Select

IHC-plus™ GRB2 Antibody (aa206-217) LS-B3923

(4.0) Rating

Antibody:

GRB2 Goat anti-Human Polyclonal (aa206-217) Antibody

Reactivity:

Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Pig, Horse, Bat, Human, Monkey

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µg/$485

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IHC-plus™ GRB2 Antibody (C-Terminus, clone Polyclonal) LS-B4508

(4.0) Rating

Antibody:

GRB2 Rabbit anti-Human Polyclonal (C-Terminus) (Polyclonal) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

0.05 mg/$460

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GRB2 Antibody (aa89-118) LS-C100001

Antibody:

GRB2 Rabbit anti-Human Polyclonal (aa89-118) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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IHC-plus™ GRB2 Antibody LS-B3068

(4.0) Rating

Antibody:

GRB2 Mouse anti-Rat Monoclonal Antibody

Reactivity:

Mouse, Bovine, Rat, Hamster, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$485

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Human GRB2 (Sandwich ELISA) ELISA Kit - LS-F21192

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.157 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

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GRB2 Antibody (phospho-Ser159) LS-C199021

Antibody:

GRB2 Rabbit anti-Human Polyclonal (pSer159) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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Mouse GRB2 (Sandwich ELISA) ELISA Kit - LS-F38341

Type:

Sandwich

Format:

12 x 8-Well Microstrips

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

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Human GRB2 Protein (Recombinant 6His, C-terminus) (Met1-Val217) - LS-G39563

Source:

E. coli

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

26.3kD

Price:

10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,157

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GRB2 Antibody (Tyr209) LS-C327492

Antibody:

GRB2 Rabbit anti-Human Polyclonal (Tyr209) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

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GRB2 Antibody (Tyr209, Biotin) LS-C244549

Antibody:

GRB2 Rabbit anti-Human Polyclonal (Tyr209) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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GRB2 Antibody (Tyr209, FITC) LS-C244551

Antibody:

GRB2 Rabbit anti-Human Polyclonal (Tyr209) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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GRB2 Antibody (Tyr209, APC) LS-C244548

Antibody:

GRB2 Rabbit anti-Human Polyclonal (Tyr209) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

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GRB2 Antibody (Tyr209, PE) LS-C244556

Antibody:

GRB2 Rabbit anti-Human Polyclonal (Tyr209) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

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GRB2 Antibody (Tyr209, Azide-free, HRP) LS-C247612

Antibody:

GRB2 Rabbit anti-Human Polyclonal (Tyr209) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• PE
• HRP, Azide-free

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • PE
  • HRP, Azide-free

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GRB2 Antibody (Biotin) LS-C396053

Antibody:

GRB2 Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

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GRB2 Antibody LS-C755178

Antibody:

GRB2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

100 µg/$331

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IHC-plus™ GRB2 Antibody LS-B4079

(4.0) Rating

Antibody:

GRB2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

Select

GRB2 Antibody LS-C334220

Antibody:

GRB2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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GRB2 Antibody LS-C805087

Antibody:

GRB2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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GRB2 Antibody LS-C341215

Antibody:

GRB2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

50 µl/$356; 100 µl/$461

Select

GRB2 Antibody LS-C766994

Antibody:

GRB2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

GRB2 Antibody (clone 3F2) LS-C179884

Antibody:

GRB2 Mouse Monoclonal (3F2) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, WB

Format:

Unconjugated

Price:

100 µg/$403

Select

GRB2 Antibody (clone 4C6-H6) LS-C197345

Antibody:

GRB2 Mouse anti-Human Monoclonal (4C6-H6) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$423

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GRB2 Antibody LS-C813220

Antibody:

GRB2 Mouse anti-Human Monoclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$332; 100 µg/$404; 200 µg/$505

Select

GRB2 Antibody (Preservative Free) LS-C343068

Antibody:

GRB2 Rabbit anti-Human Polyclonal (Preservative Free) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated, Preservative Free

Price:

20 µg/$242; 100 µg/$304; 200 µg/$334; 500 µg/$452

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