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FTL / Ferritin Light Chain

ferritin, light polypeptide

FTL / Ferritin Light Chain is the light subunit of the ferritin protein. Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in this light chain ferritin gene are associated with several neurodegenerative diseases and hyperferritinemia-cataract syndrome. This gene has multiple pseudogenes.

Gene Name: ferritin, light polypeptide
Synonyms: FTL, Ferritin L subunit, Ferritin L-chain, Ferritin, light polypeptide, Ferritin light chain, NBIA3
Target Sequences: NM_000146 NP_000137.2 P02792

Publications (3)

1
Ferritin in glioblastoma. Heidi Jaksch-Bogensperger , Sabine Spiegl-Kreinecker, Paolo Arosio, Peter Eckl, Stefan Golaszewski, Yvonne Ebner, Rahman Al-Schameri, Peter Strasser, Serge Weis , Nikolaus Bresgen. British journal of cancer. 2020 May;122:1441-1444. [Full Text Article] [PubMed:32203223] [PMC:PMC7217840] Related Antibodies: LS-B4383.
2
Multitissue analysis of exercise and metformin on doxorubicin-induced iron dysregulation. Amy D Mackay, Erik D Marchant, Devin J Munk, Richard K Watt, Jason M Hansen, David M Thomson, Chad R Hancock. American journal of physiology. Endocrinology and metabolism. 2019 May;316:E922-E930. [Full Text Article] [PubMed:30888858]
3
Unbalance in Iron Metabolism in Childhood Leukemia Converges with Treatment Intensity: Biochemical and Clinical Analysis. Monika Lecka, Artur Slomka, Katarzyna Albrecht, Ewa Zekanowska, Michal Romiszewski, Jan Styczynski. Cancers. 2021 June;13:3029. [Full Text Article] [PubMed:34204310] [PMC:PMC8233795]

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Antibodies (79)
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FTL / Ferritin Light Chain Antibody - Anti-FTL antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
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Cancer
FTL / Ferritin Light Chain Goat anti-Human Polyclonal (aa150-200) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
FTL / Ferritin Light Chain Antibody
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FTL / Ferritin Light Chain Mouse anti-Human Monoclonal (FTLC1-1) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
20 µg/$371; 100 µg/$574
FTL / Ferritin Light Chain Antibody -  This image was taken for the unmodified form of this product. Other forms have not been tested.
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FTL / Ferritin Light Chain Mouse anti-Human Monoclonal (Azide-free, BSA-free) (FTLC1-1) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated, Azide-free, BSA-free
100 µg/$574
FTL / Ferritin Light Chain ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$748
FTL / Ferritin Light Chain ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.39 - 25 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$730
FTL / Ferritin Light Chain ELISA Kit
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Sandwich
96-Well Strip Plate
Dog
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$585
FTL / Ferritin Light Chain ELISA Kit
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Sandwich
96-Well Microplate
Human
3.13 - 200 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$771
FTL / Ferritin Light Chain Protein
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E. coli
None
100 µg/$411; 500 µg/$985; 20 µg/$276
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FTL / Ferritin Light Chain Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
FTL / Ferritin Light Chain ELISA Kit
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Sandwich
96-Well Strip Plate
Human
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$441
FTL / Ferritin Light Chain Protein - Recombinant Ferritin, Light Polypeptide By SDS-PAGE
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E. coli
His, N-Terminal
24.0 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
FTL / Ferritin Light Chain Antibody - Immunohistochemistry of paraffin-embedded human amygdalitis using FTL antibodyat dilution of 1:100 (40x lens).
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FTL / Ferritin Light Chain Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
FTL / Ferritin Light Chain Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Cancer
FTL / Ferritin Light Chain Rabbit anti-Human Recombinant Monoclonal (aa 38-165) (FTL/2338R) Antibody
Human
IHC-P, WB
Unconjugated
100 µg/$525
FTL / Ferritin Light Chain ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
100 - 2500 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$805
FTL / Ferritin Light Chain Antibody - Human Lung: Formalin-Fixed, Paraffin-Embedded (FFPE)
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FTL / Ferritin Light Chain Rabbit anti-Human Polyclonal Antibody
Mouse, Pig, Human
IHC-P, WB
Unconjugated
50 µl/$460
FTL / Ferritin Light Chain Antibody
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FTL / Ferritin Light Chain Rabbit anti-Human Polyclonal (HRP) Antibody
Pig, Human
WB
HRP Conjugated
100 µl/$338; 200 µl/$393; 500 µl/$575; 1 ml/$702; 2 ml/$939; 5 ml/$1,593
FTL / Ferritin Light Chain Antibody
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FTL / Ferritin Light Chain Rabbit anti-Human Polyclonal (APC, Cy7) Antibody
Pig, Human
WB
APC, Cy7 Conjugated
100 µl/$505; 200 µl/$648; 500 µl/$1,152; 1 ml/$1,401; 2 ml/$1,961; 5 ml/$3,676
FTL / Ferritin Light Chain Antibody - Anti-FTL / Ferritin Light Chain antibody IHC staining of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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FTL / Ferritin Light Chain Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
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FTL / Ferritin Light Chain Rabbit anti-Human Polyclonal Antibody
Rabbit, Rat, Pig, Human
ELISA, WB
Unconjugated
50 µl/$553; 100 µl/$832
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FTL / Ferritin Light Chain Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
100 µl/$375; 200 µl/$473; 400 µl/$648
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FTL / Ferritin Light Chain Mouse anti-Human Monoclonal (8E1E7) Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µl/$459
FTL / Ferritin Light Chain Antibody - Biotinylated Goat Anti-FTL antibody (1µg/ml) staining of Rat Brain lysate (35µg protein in RIPA buffer), exactly mirroring its parental non-biotinylated product. Primary incubation was 1 hour. Detected by chemiluminescencence, using streptavidin-HRP and using NAP blocker as a substitute for skimmed milk.
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FTL / Ferritin Light Chain Goat anti-Human Polyclonal (Biotin) Antibody
Human
Peptide-ELISA, WB
Biotin Conjugated
100 µg/$503
FTL / Ferritin Light Chain Antibody - 1:100 staining human prostate tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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FTL / Ferritin Light Chain Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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FTL / Ferritin Light Chain Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$331
FTL / Ferritin Light Chain Antibody - Anti-FTL / Ferritin Light Chain antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5-7.5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Cancer
FTL / Ferritin Light Chain Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
Viewing 1-25 of 117 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).