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FN1 / Fibronectin
fibronectin 1
Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts.Anastellin binds fibronectin and induces fibril formation. This fibronectin polymer, named superfibronectin, exhibits enhanced adhesive properties. Both anastellin and superfibronectin inhibit tumor growth, angiogenesis and metastasis. Anastellin activates p38 MAPK and inhibits lysophospholipid signaling.
| Gene Name: | fibronectin 1 |
| Synonyms: | FN1, CIG, Cold-insoluble globulin, Fibronectin 1, FINC, LETS, GFND, ED-B, Fibronectin, FN, FNZ, GFND2, Migration-stimulating factor, MSF |
| Target Sequences: | NM_002026 NP_002017.1 P02751 |
Publications (5)
1
Structural and Functional Characterization of Fibronectin in Extracellular Vesicles From Hepatocytes. Xinlei Li, Ruju Chen, Sherri Kemper, David R Brigstock. Frontiers in cell and developmental biology. 2021 Mar;9:640667. [Full Text Article]
[PubMed:33816490]
[PMC:PMC8012540]
2
Interventricular Differences of Signaling Pathways-Mediated Regulation of Cardiomyocyte Function in Response to High Oxidative Stress in the Post-Ischemic Failing Rat Heart. Árpád Kovács , Melissa Herwig , Heidi Budde , Simin Delalat , Detmar Kolijn , Beáta Bódi, Roua Hassoun , Melina Tangos , Saltanat Zhazykbayeva , Ágnes Balogh, Dániel Czuriga, Sophie Van Linthout, Carsten Tschöpe, Naranjan S Dhalla, Andreas Mügge , Attila Tóth , Zoltán Papp , Judit Barta, Nazha Hamdani. Antioxidants. 2021 Jun;10:964. [Full Text Article]
[PubMed:34208541]
[PMC:PMC8234177]
3
Long-Term Dipeptidyl Peptidase 4 Inhibition Worsens Hypertension and Renal and Cardiac Abnormalities in Obese Spontaneously Hypertensive Heart Failure Rats. Edwin K Jackson, Zaichuan Mi, Delbert G Gillespie, Dongmei Cheng, Stevan P Tofovic. Journal of the American Heart Association. 2021 March;10:e020088. [Full Text Article]
[PubMed:33682436]
[PMC:PMC8174220]
☰ Filters
Products
Proteins
(22)
Type
Native
(2)
Over-Expression Lysate
(6)
Recombinant
(14)
Target
FN1 / Fibronectin
(22)
Publications
No
(22)
Tag
6His, N-terminus
(1)
GST
(1)
His
(6)
His, N-Terminal
(4)
His-AVI, N-terminus
(1)
Myc-DDK (Flag)
(6)
Species
Bovine
(1)
Chicken
(1)
Cow
(1)
Human
(14)
Mouse
(1)
Rat
(1)
Source
293T Cells
(3)
E. coli
(12)
HEK 293 Cells
(3)
Human Cells
(1)
Mammalian Cells
(1)
Wheat Germ Extract
(1)
Purification
Purified
(5)
Low Endotoxin Level
Low endotoxin level
(4)
E. coli
His, N-Terminal
14.8 kDa
10 µg/$267; 50 µg/$352; 100 µg/$562; 200 µg/$702; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900
HEK 293 Cells
Myc-DDK (Flag)
71.2 kDa
100 µg/$710
HEK 293 Cells
Myc-DDK (Flag)
237.1 kDa
100 µg/$710
HEK 293 Cells
Myc-DDK (Flag)
269.8 kDa
100 µg/$710
293T Cells
Myc-DDK (Flag)
237.1 kDa
20 µg/$215
293T Cells
Myc-DDK (Flag)
71.2 kDa
20 µg/$215
293T Cells
Myc-DDK (Flag)
269.8 kDa
20 µg/$215
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
62.7 kDa
50 µg/$288; 10 µg/$240; 1 mg/$603; 500 µg/$462
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
62.7 kDa
10 µg/$233; 50 µg/$269
E. coli
His-AVI, N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
13.4 kDa
20 µg/$416; 100 µg/$910
E. coli
His, N-Terminal
34.9kDa
10 µg/$291; 50 µg/$505; 200 µg/$1,008; 100 µg/$807; 1 mg/$2,153; 500 µg/$1,676; 5 mg/$3,529; 2 mg/$2,344
E. coli
His, N-Terminal
26kDa
10 µg/$300; 50 µg/$562; 200 µg/$1,096; 100 µg/$897; 1 mg/$2,284; 500 µg/$1,796; 5 mg/$3,921; 2 mg/$2,476
E. coli
6His, N-terminus
18 kDa
10 µg/$265; 50 µg/$315; 100 µg/$365
Wheat Germ Extract
GST
43.56 kDa
10 µg/$479; 25 µg/$670
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
73.2 kDa
100 µg/$451; 1 mg/$2,093
E. coli
His
24.7 kDa
10 µg/$239; 50 µg/$283; 100 µg/$326; 200 µg/$362; 1 mg/$1,065; 500 µg/$722; 5 mg/$1,858; 2 mg/$1,200
E. coli
His
21.2 kDa
10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
E. coli
His
35.2 kDa
10 µg/$255; 50 µg/$323; 100 µg/$450; 200 µg/$562; 1 mg/$1,480; 500 µg/$1,096; 5 mg/$2,395; 2 mg/$1,646
E. coli
His
16.1 kDa
10 µg/$255; 50 µg/$323; 100 µg/$450; 200 µg/$562; 1 mg/$1,480; 500 µg/$1,096; 5 mg/$2,395; 2 mg/$1,646
E. coli
His
13.6 kDa
10 µg/$255; 50 µg/$323; 100 µg/$450; 200 µg/$562; 1 mg/$1,480; 500 µg/$1,096; 5 mg/$2,395; 2 mg/$1,646
Mammalian Cells
His, N-Terminal
10 µg/$275; 50 µg/$402; 200 µg/$802; 100 µg/$642; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060
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