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FMR1 / FMRP
fragile X mental retardation 1
Translation repressor. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates translation repression (By similarity). RNA-binding protein that plays a role in intracellular RNA transport and in the regulation of translation of target mRNAs. Associated with polysomes. May play a role in the transport of mRNA from the nucleus to the cytoplasm. Binds strongly to poly(G), binds moderately to poly(U) but shows very little binding to poly(A) or poly(C).
| Gene Name: | fragile X mental retardation 1 |
| Synonyms: | FMR1, FMRP, POF, Protein FMR-1, Premature ovarian failure 1, Fragile X mental retardation 1, FRAXA, POF1 |
| Target Sequences: | NM_002024 NP_002015.1 Q06787 |
Publications (1)
1
Identification of FMRP target mRNAs in the developmental brain: FMRP might coordinate Ras/MAPK, Wnt/ß-catenin, and mTOR signaling during corticogenesis. Cristine R Casingal, Takako Kikkawa, Hitoshi Inada , Yukio Sasaki, Noriko Osumi. Molecular brain. 2020 Dec;13:167. [Full Text Article]
[PubMed:33323119]
[PMC:PMC7739466]
Related Antibodies: LS-B3953.
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FMR1 / FMRP Goat anti-Human Polyclonal (aa594-607) Antibody
Rabbit, Mouse, Rat, Hamster, Pig, Bat, Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
FMR1 / FMRP Mouse anti-Human Monoclonal (1D10) Antibody
Mouse, Dog, Rat, Human, Monkey
IHC, IHC-P, WB
Unconjugated
50 µl/$460
FMR1 / FMRP Goat anti-Human Polyclonal (aa116-130) Antibody
Rabbit, Mouse, Dog, Rat, Hamster, Pig, Bat, Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
FMR1 / FMRP Mouse anti-Human Monoclonal (aa36-279) (OTI5B9) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
FMR1 / FMRP Mouse anti-Human Monoclonal (aa36-279) (Carrier-free) (OTI5B9) Antibody
Human
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
FMR1 / FMRP Mouse anti-Human Monoclonal (N-Terminus) (1C3) Antibody
Mouse, Rat, Human
ELISA, ICC, IHC, IHC-Fr, IHC-P, WB
Unconjugated
100 µl/$957
FMR1 / FMRP Mouse anti-Human Monoclonal (OTI2C3) Antibody
Mouse, Dog, Rat, Human, Monkey
IHC, IHC-P, WB
Unconjugated
100 µl/$434
Sandwich
96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$834
Sandwich
96-Well Strip Plate
Human
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$958
HEK 293 Cells
Myc-DDK (Flag)
71 kDa
20 µg/$1,107
FMR1 / FMRP Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.05 mg/$460
FMR1 / FMRP Mouse anti-Human Monoclonal (4G9) Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µl/$435
FMR1 / FMRP Rabbit anti-Human Polyclonal (aa20-48) Antibody
Mouse, Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
FMR1 / FMRP Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
![FMR1 / FMRP Antibody - Immunoprecipitation - Drosophila FMR1 antibody [6A15] using tissue lysate from Drosophila cellularizing embryos](https://lsbio-7d62.kxcdn.com/image2/fmr1-fmrp-antibody-n-terminus-clone-6a15-ls-c82231/127568_5025665.jpg)
FMR1 / FMRP Mouse anti-Drosophila Monoclonal (N-Terminus) (6A15) Antibody
Drosophila
ELISA, IF, IP, WB
Unconjugated
0.1 mg/$482
FMR1 / FMRP Mouse anti-Human Monoclonal (OTI1C6) Antibody
Mouse, Dog, Rat, Human, Monkey
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
FMR1 / FMRP Mouse anti-Human Monoclonal (aa36-279) (Carrier-free) (OTI1C6) Antibody
Mouse, Dog, Rat, Human, Monkey
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
FMR1 / FMRP Mouse anti-Human Monoclonal (OTI3B4) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
FMR1 / FMRP Mouse anti-Human Monoclonal (Carrier-free) (OTI3B4) Antibody
Human
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
FMR1 / FMRP Mouse anti-Human Monoclonal (4G9) Antibody
Mouse, Human
ICC, IF, IHC, WB
Unconjugated
100 µl/$541
FMR1 / FMRP Mouse anti-Human Monoclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$332; 100 µg/$404; 200 µg/$505
FMR1 / FMRP Mouse anti-Human Monoclonal Antibody
Mouse, Rat, Human
ELISA, ICC, IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated
10 Tests/$926
FMR1 / FMRP Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IP, WB
Unconjugated
100 µg/$331
FMR1 / FMRP Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
FMR1 / FMRP Rabbit anti-Rat Polyclonal (aa421-470) Antibody
Rat
WB
Unconjugated
100 µl/$424
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