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| Catalog Number | Size | Price |
|---|---|---|
| LS-B3953-50 | 50 µg (0.5 mg/ml) | $485 |
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2 of 2
IHC‑plus™ Polyclonal Goat anti‑Human FMR1 / FMRP Antibody (aa594‑607, IHC, WB) LS‑B3953
IHC‑plus™ Polyclonal Goat anti‑Human FMR1 / FMRP Antibody (aa594‑607, IHC, WB) LS‑B3953
Note: This antibody replaces LS-C87208
Antibody:
FMR1 / FMRP Goat anti-Human Polyclonal (aa594-607) Antibody
Application:
IHC, IHC-P, WB, Peptide-ELISA
Reactivity:
Human, Monkey, Mouse, Rat, Bat, Hamster, Pig, Rabbit
Format:
Unconjugated, Unmodified
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
FMR1 / FMRP Goat anti-Human Polyclonal (aa594-607) Antibody
Application:
IHC, IHC-P, WB, Peptide-ELISA
Reactivity:
Human, Monkey, Mouse, Rat, Bat, Hamster, Pig, Rabbit
Format:
Unconjugated, Unmodified
Specifications
Description
FMRP antibody LS-B3953 is an unconjugated goat polyclonal antibody to FMRP (FMR1) (aa594-607) from human. It is reactive with human, mouse, rat and other species. Validated for IHC, Peptide-ELISA and WB. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
Target
Human FMR1 / FMRP
Synonyms
FMR1 | FMRP | POF | Protein FMR-1 | Premature ovarian failure 1 | Fragile X mental retardation 1 | FRAXA | POF1
Host
Goat
Reactivity
Human, Monkey, Mouse, Rat, Bat, Hamster, Pig, Rabbit
(tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Modifications
Unmodified
Immunogen
Peptide with sequence C-RTGKDRNQKKEKPD, from the internal region (near the C-Terminus) of the protein sequence according to NP_002015.1.
Epitope
aa594-607
Specificity
Human FMR1.
Applications
- IHC
- IHC - Paraffin (2.5 µg/ml)
- Western blot (0.1 - 0.3 µg/ml)
- Peptide Enzyme-Linked Immunosorbent Assay (1:128000)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Peptide ELISA: antibody detection limit dilution 1:128000. Western Blot: Approx 80kD band observed in lysates of cell line KELLY (calculated MW of 71.2kD according to NP_002015.1). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Sittler et al, Hum Mol Genet. 1996 Jan;5(1):95-102; PMID: 8789445). Recommended concentration: 0.1-0.3 ug/ml.
Presentation
TBS, pH 7.3, 0.02% Sodium Azide, 0.5% BSA
Storage
Aliquot and store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About FMR1 / FMRP
Validation
Anti-FMR1 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.
Anti-FMR1 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.
See More About...
LSBio Ratings
IHC-plus™ FMR1 / FMRP Antibody (aa594-607) for IHC, WB/Western LS-B3953 has an LSBio Rating of
Publications (4)
Laboratory Validation Score (4)
Learn more about The LSBio Ratings Algorithm
Publications (1)
Identification of FMRP target mRNAs in the developmental brain: FMRP might coordinate Ras/MAPK, Wnt/ß-catenin, and mTOR signaling during corticogenesis. Cristine R Casingal, Takako Kikkawa, Hitoshi Inada , Yukio Sasaki, Noriko Osumi. Molecular brain. 2020 Dec;13:167.
Customer Reviews (0)
Featured Products
Species:
Human, Monkey, Mouse, Rat, Bat, Dog, Hamster, Pig, Rabbit
Applications:
IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Human, Mouse, Rat
Applications:
IHC, IHC - Paraffin, IHC - Frozen, ICC, Western blot, ELISA
Species:
Human
Applications:
IHC, Immunofluorescence, Western blot, ELISA
Species:
Human, Mouse, Rat
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Species:
Human, Mouse
Applications:
IHC, IHC - Paraffin, Western blot, Flow Cytometry
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/22/2024
Date Requested: 11/22/2024
