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6737 Mowry Ave
Newark, CA 94560
United States
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FBXO3
F-box protein 3
FBXO3 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternative splicing of this gene generates 2 transcript variants diverging at the 3' end.
| Gene Name: | F-box protein 3 |
| Family/Subfamily: | F-Box |
| Synonyms: | FBXO3, F-box protein 3, F-box protein FBX3, F-box only protein 3, FBA, FBX3 |
| Target Sequences: | NM_012175 NP_036307.2 Q9UK99 |
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