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| Catalog Number | Size | Price |
|---|---|---|
| LS-C502157-50 | 50 µg (4 mg/ml) | $294 |
| LS-C502157-100 | 100 µg (4 mg/ml) | $360 |
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Polyclonal Rabbit anti‑Human FBXO3 Antibody (IHC, IF) LS‑C502157
Polyclonal Rabbit anti‑Human FBXO3 Antibody (IHC, IF) LS‑C502157
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Specifications
Description
FBXO3 antibody LS-C502157 is an unconjugated rabbit polyclonal antibody to FBXO3 from human. It is reactive with human and mouse. Validated for ELISA, IF and IHC.
Target
Human FBXO3
Synonyms
FBXO3 | F-box protein 3 | F-box protein FBX3 | F-box only protein 3 | FBA | FBX3
Host
Rabbit
Reactivity
Human, Mouse
(tested or 100% immunogen sequence identity)
Clonality
IgG
Polyclonal
Purification
Protein G purified
Modifications
Unmodified
Immunogen
Recombinant Human F-box only protein 3 protein (276-376AA)
Specificity
Substrate recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Mediates the ubiquitination of HIPK2 and probably that of EP300, leading to rapid degradation by the proteasome. In the presence of PML, HIPK2 ubiquitination still occurs, but degradation is prevented. PML, HIPK2 and FBXO3 may act synergically to activate p53/TP53-dependent transactivation.
Applications
- IHC
- Immunofluorescence
- ELISA
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Storage
Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About FBXO3
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Featured Products
Species:
Human
Applications:
Western blot, Flow Cytometry, ELISA
Species:
Human
Applications:
Western blot, Flow Cytometry, ELISA
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 12/22/2024
Date Requested: 12/22/2024
