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FBN1 / Fibrillin 1
fibrillin 1
Fibrillins are structural components of 10-12 nm extracellular calcium-binding microfibrils, which occur either in association with elastin or in elastin-free bundles. Fibrillin-1-containing microfibrils provide long-term force bearing structural support. Regulates osteoblast maturation by controlling TGF-beta bioavailability and calibrating TGF-beta and BMP levels, respectively.
| Gene Name: | fibrillin 1 |
| Synonyms: | FBN1, ACMICD, Fibrillin 1, Fibrillin-1, FBN, ECTOL1, GPHYSD2, MASS, MFS1, OCTD, SSKS, WMS2, Fibrillin 1 (Marfan syndrome), Fibrillin 15, SGS, WMS |
| Target Sequences: | NM_000138 P35555 |
Publications (4)
1
Defining the Extracellular Matrix of Rhabdomyosarcoma. Xiaolei Lian, J Steffan Bond, Narendra Bharathy, Sergei P Boudko, Elena Pokidysheva, Jack F Shern, Melvin Lathara, Takako Sasaki, Teagan Settelmeyer, Megan M Cleary, Ayeza Bajwa, Ganapati Srinivasa, Christopher P Hartley, Hans Peter Bächinger, Atiya Mansoor, Sakir H Gultekin, Noah E Berlow, Charles Keller. Frontiers in oncology. 2021 March;11:601957. [Full Text Article]
[PubMed:33708626]
[PMC:PMC7942227]
Related Antibodies: LS-B5512.
2
FBXO2 Promotes Proliferation of Endometrial Cancer by Ubiquitin-Mediated Degradation of FBN1 in the Regulation of the Cell Cycle and the Autophagy Pathway. Xiaoxia Che, Fangfang Jian, Ying Wang, Jingjing Zhang, Jian Shen, Qi Cheng, Xi Wang, Nan Jia, Weiwei Feng. Frontiers in cell and developmental biology. 2020 September;8:843. [Full Text Article]
[PubMed:32984335]
[PMC:PMC7487413]
Related Antibodies: LS-B5512.
3
Impairment of chondrogenesis and microfibrillar network in Adamtsl2 deficiency. Laure Delhon, Clémentine Mahaut, Nicolas Goudin, Emilie Gaudas, Kevin Piquand, Wilfried Le Goff, Valérie Cormier-Daire, Carine Le Goff. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2019 Feb;33:2707-2718. [Full Text Article]
[PubMed:30303737]
Related Antibodies: LS-C358981.
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Antibodies
(127)
Type
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(127)
Target
FBN1 / Fibrillin 1
(127)
Reactivity
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(80)
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(39)
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(36)
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(18)
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(12)
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(3)
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(18)
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(10)
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(115)
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(20)
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(9)
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(17)
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(14)
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(3)
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(108)
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(18)
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(1)
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(3)
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(1)
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(15)
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(13)
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(4)
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(18)
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(109)
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(10)
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(12)
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(19)
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(10)
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(10)
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(19)
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(14)
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(12)
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(31)
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(1)
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(1)
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(1)
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(1)
Publications
No
(125)
Yes
(2)
FBN1 / Fibrillin 1 Mouse anti-Human Monoclonal (aa45-450) (26) Antibody
Chicken, Bovine, Human
ELISA, IF, IHC, IHC-P, IP, WB
Unconjugated
50 µg/$485
FBN1 / Fibrillin 1 Mouse anti-Human Monoclonal (Biotin) Antibody
Chicken, Bovine, Human
ELISA, IF, IP, WB
Biotin Conjugated
100 µl/$1,149
FBN1 / Fibrillin 1 Mouse anti-Human Monoclonal (FITC) Antibody
Chicken, Bovine, Human
ELISA, IF, IP, WB
FITC Conjugated
100 µl/$1,149
FBN1 / Fibrillin 1 Mouse anti-Human Monoclonal (PE) Antibody
Chicken, Bovine, Human
ELISA, IF, IP, WB
PE Conjugated
100 µl/$1,149
FBN1 / Fibrillin 1 Mouse anti-Human Monoclonal (APC) Antibody
Chicken, Bovine, Human
ELISA, IF, IP, WB
APC Conjugated
100 µl/$1,149
FBN1 / Fibrillin 1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Bovine, Rat, Pig, Human
ICC, IF, WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
FBN1 / Fibrillin 1 Mouse anti-Human Monoclonal (3H6) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$440
FBN1 / Fibrillin 1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
FBN1 / Fibrillin 1 Rabbit anti-Human Polyclonal (2780-2860 aa, C-terminal) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
FBN1 / Fibrillin 1 Rabbit anti-Human Polyclonal (Asn2843) Antibody
Mouse, Rat, Human
IHC, IHC-P
Unconjugated
50 µl/$321; 100 µl/$403
FBN1 / Fibrillin 1 Rabbit anti-Human Polyclonal (aa723-902) (Biotin) Antibody
Human
ICC, WB
Biotin Conjugated
100 µl/$307
FBN1 / Fibrillin 1 Rabbit anti-Human Polyclonal Antibody
Bovine, Human
ELISA, ICC, IHC-P
Unconjugated
50 µl/$485
FBN1 / Fibrillin 1 Mouse anti-Human Monoclonal (aa2093-2871) Antibody
Chicken, Bovine, Human
ELISA, IF, IP, WB
Unconjugated
100 µg/$854
FBN1 / Fibrillin 1 Mouse anti-Human Monoclonal (HRP) Antibody
Chicken, Bovine, Human
ELISA, IF, IP, WB
HRP Conjugated
100 µl/$1,149
FBN1 / Fibrillin 1 Mouse anti-Human Monoclonal (Biotin) Antibody
Chicken, Bovine, Human
ELISA, IF, IP, WB
Biotin Conjugated
100 µl/$1,149
FBN1 / Fibrillin 1 Mouse anti-Human Monoclonal (FITC) Antibody
Chicken, Bovine, Human
ELISA, IF, IP, WB
FITC Conjugated
100 µl/$1,149
FBN1 / Fibrillin 1 Mouse anti-Human Monoclonal (APC) Antibody
Chicken, Bovine, Human
ELISA, IF, IP, WB
APC Conjugated
100 µl/$1,149
FBN1 / Fibrillin 1 Mouse anti-Human Monoclonal (PE) Antibody
Chicken, Bovine, Human
ELISA, IF, IP, WB
PE Conjugated
100 µl/$1,149
FBN1 / Fibrillin 1 Rabbit anti-Human Polyclonal (aa2811-2860) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
FBN1 / Fibrillin 1 Rabbit anti-Mouse Polyclonal (aa1701-1887) Antibody
Mouse
WB
Unconjugated
100 µl/$301; 200 µl/$340; 500 µl/$470; 1 ml/$535; 2 ml/$698; 5 ml/$1,161
FBN1 / Fibrillin 1 Rabbit anti-Human Polyclonal (aa246-389) Antibody
Human
WB
Unconjugated
100 µl/$299; 200 µl/$337; 500 µl/$463; 1 ml/$527; 2 ml/$682; 5 ml/$1,141
FBN1 / Fibrillin 1 Rabbit anti-Human Polyclonal (aa723-902) Antibody
Human
WB
Unconjugated
100 µl/$299; 200 µl/$336; 500 µl/$462; 1 ml/$525; 2 ml/$677; 5 ml/$1,136
FBN1 / Fibrillin 1 Rabbit anti-Mouse Polyclonal (aa1701-1887) (FITC) Antibody
Mouse
WB
FITC Conjugated
100 µl/$319
FBN1 / Fibrillin 1 Rabbit anti-Rat Polyclonal (aa751-895) Antibody
Rat
WB
Unconjugated
100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206
FBN1 / Fibrillin 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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product results
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