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| Catalog Number | Size | Price |
|---|---|---|
| LS-B5512-50 | 50 µg (1 mg/ml) | $485 |
IHC‑plus™ Monoclonal Mouse anti‑Human FBN1 / Fibrillin 1 Antibody (clone 26, aa45‑450, IHC, IF, WB) LS‑B5512
IHC‑plus™ Monoclonal Mouse anti‑Human FBN1 / Fibrillin 1 Antibody (clone 26, aa45‑450, IHC, IF, WB) LS‑B5512
Note: This antibody replaces LS-C23549
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Specifications
Description
Fibrillin 1 antibody LS-B5512 is an unconjugated mouse monoclonal antibody to Fibrillin 1 (FBN1) (aa45-450) from human. It is reactive with human, bovine and chicken. Validated for ELISA, IF, IHC, IP and WB. Tested on 20 paraffin-embedded human tissues. Cited in 2 publications.
Target
Human FBN1 / Fibrillin 1
Synonyms
FBN1 | ACMICD | Fibrillin 1 | Fibrillin-1 | FBN | ECTOL1 | GPHYSD2 | MASS | MFS1 | OCTD | SSKS | WMS2 | Fibrillin 1 (Marfan syndrome) | Fibrillin 15 | SGS | WMS
Host
Mouse
Reactivity
Human, Bovine, Chicken
(tested or 100% immunogen sequence identity)
Clonality
IgG1
Monoclonal
Clone
26
Purification
Purified
Modifications
Unmodified
Immunogen
Human Fibrillin-1
Epitope
aa45-450
Specificity
Recognizes human Fibrillin-1. Epitope mapping studies identify the binding site of this antibody to amino terminal end of the molecule, between amino acid residues 45 and 450. Species cross-reactivity: Human, chicken and bovine.
Applications
- IHC
- IHC - Paraffin (10 µg/ml)
- Immunofluorescence
- Western blot
- Immunoprecipitation
- ELISA
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Suitable for use in Western Blot, Immunofluorescence, Immunoprecipitation and ELISA.
Presentation
PBS, pH 7.6, 0.09% Sodium Azide
Storage
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Validation
Anti-FBN1 / Fibrillin 1 antibody IHC of human prostate, extra cellular matrix. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-FBN1 / Fibrillin 1 antibody IHC of human prostate, extra cellular matrix. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
See More About...
LSBio Ratings
IHC-plus™ FBN1 / Fibrillin 1 Antibody (aa45-450, clone 26) for IHC, IF/Immunofluorescence, WB/Western, IP, ELISA LS-B5512 has an LSBio Rating of
Publications (4.1)
Laboratory Validation Score (4)
Learn more about The LSBio Ratings Algorithm
Publications (2)
Defining the Extracellular Matrix of Rhabdomyosarcoma. Xiaolei Lian, J Steffan Bond, Narendra Bharathy, Sergei P Boudko, Elena Pokidysheva, Jack F Shern, Melvin Lathara, Takako Sasaki, Teagan Settelmeyer, Megan M Cleary, Ayeza Bajwa, Ganapati Srinivasa, Christopher P Hartley, Hans Peter Bächinger, Atiya Mansoor, Sakir H Gultekin, Noah E Berlow, Charles Keller. Frontiers in oncology. 2021 March;11:601957.
FBXO2 Promotes Proliferation of Endometrial Cancer by Ubiquitin-Mediated Degradation of FBN1 in the Regulation of the Cell Cycle and the Autophagy Pathway. Xiaoxia Che, Fangfang Jian, Ying Wang, Jingjing Zhang, Jian Shen, Qi Cheng, Xi Wang, Nan Jia, Weiwei Feng. Frontiers in cell and developmental biology. 2020 September;8:843.
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Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot, ELISA
Species:
Human, Mouse, Rat, Bovine, Pig
Applications:
ICC, Immunofluorescence, Western blot
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human, Mouse, Rat
Applications:
IHC, IHC - Paraffin
Species:
Human, Bovine, Chicken
Applications:
Immunofluorescence, Western blot, Immunoprecipitation, ELISA
Reactivity:
Human
Range:
0.312-20 ng/ml
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 12/30/2024
Date Requested: 12/30/2024
