Products
Research Areas
COVID-19
Resources
Login
Quick Order
Cart Cart lightblue
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Contact Us

Location


Corporate Headquarters

Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States

Telephone Numbers



Customer Service: (800) 227-6666 / (650) 697-3600


Contact Us



Additional Contact Details

Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order

F8 / FVIII / Factor VIII

coagulation factor VIII, procoagulant component

F8 / FVIII / Factor VIII is coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder.

Gene Name: coagulation factor VIII, procoagulant component
Synonyms: F8, AHF, Antihemophilic factor, Coagulation factor VIIIc, Coagulation factor VIII, DXS1253E, Factor VIII F8B, FVIII, HEMA, F8B, Factor VIII, Procoagulant component, F8C
Target Sequences: NM_000132 NP_000123.1 P00451

Publications (2)

1
Von Willebrand and Factor VIII Portosystemic Circulation Gradient in Cirrhosis: Implications for Portal Vein Thrombosis. Von Willebrand and Factor VIII Portosystemic Circulation Gradient in Cirrhosis: Implications for Portal Vein Thrombosis. Clinical and translational gastroenterology. 2020 February;11:e00123. [Full Text Article] [PubMed:32032127] [PMC:PMC7145026]
2
IL-15 blockade and rapamycin rescue multifactorial loss of factor VIII from AAV-transduced hepatocytes in hemophilia A mice. John S S Butterfield, Kentaro Yamada, Thais B Bertolini, Farooq Syed, Sandeep R P Kumar, Xin Li, Sreevani Arisa, Annie R Piñeros, Alejandro Tapia, Christopher A Rogers, Ning Li, Jyoti Rana, Moanaro Biswas, Cox Terhorst, Randal J Kaufman, Ype P de Jong, Roland W Herzog. Molecular therapy : the journal of the American Society of Gene Therapy. 2022 December;30:3552-3569. [Full Text Article] [PubMed:35821634] [PMC:PMC9734025] Related Antibodies: LS-B2979.

☰ Filters
Products
ELISA Kits (21)
Competitive EIA (1)
Custom (1)
Sandwich (16)
Sandwich CLIA (3)
F8 / FVIII / Factor VIII (21)
Human (7)
Mouse (5)
Rat (1)
Chicken (1)
Dog (2)
Monkey (2)
Pig (1)
Rabbit (1)
Sheep (1)
12 x 8-Well Microstrips (2)
96-Well Microplate (3)
96-Well Strip Plate (16)
No (20)
Yes (1)
Cell Culture Supernatants (1)
Cell Supernatant (1)
Plasma (17)
Serum (11)
Tissue Homogenates (2)
F8 / FVIII / Factor VIII ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.78 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma
1 Plate/$798
F8 / FVIII / Factor VIII ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.0018 - 0.92 IU/ml
Colorimetric - 450nm (TMB)
Plasma
1 Plate/$940
F8 / FVIII / Factor VIII ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma
1 Plate/$715
F8 / FVIII / Factor VIII ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$669
F8 / FVIII / Factor VIII ELISA Kit
Select
Sandwich
96-Well Strip Plate
Monkey
2.344 - 150 ng/ml
Colorimetric - 450nm (TMB)
Plasma
1 Plate/$579
F8 / FVIII / Factor VIII ELISA Kit
Select
Sandwich
96-Well Strip Plate
Monkey
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$745
F8 / FVIII / Factor VIII ELISA Kit
Select
Sandwich
96-Well Microplate
Mouse
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
F8 / FVIII / Factor VIII ELISA Kit
Select
Sandwich
96-Well Microplate
Rat
7.81 - 500 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
F8 / FVIII / Factor VIII ELISA Kit
Select
Sandwich
96-Well Strip Plate
Dog
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma
1 Plate/$783
F8 / FVIII / Factor VIII ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Human
62.5 - 4000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
F8 / FVIII / Factor VIII ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
F8 / FVIII / Factor VIII ELISA Kit
Select
Sandwich CLIA
96-Well Microplate
Human
13.7 - 10000 pg/ml
Chemiluminescent
Plasma
1 Plate/$816
F8 / FVIII / Factor VIII ELISA Kit
Select
Sandwich
96-Well Strip Plate
Dog
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
F8 / FVIII / Factor VIII ELISA Kit
Select
Sandwich
96-Well Strip Plate
Pig
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
F8 / FVIII / Factor VIII ELISA Kit
Select
Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$669
F8 / FVIII / Factor VIII ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Mouse
62.5 - 4000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$656
F8 / FVIII / Factor VIII ELISA Kit
Select
Sandwich
96-Well Strip Plate
Chicken
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$565
F8 / FVIII / Factor VIII ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rabbit
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$565
F8 / FVIII / Factor VIII ELISA Kit
Select
Sandwich
96-Well Strip Plate
Sheep
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$691
F8 / FVIII / Factor VIII ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.16 - 10 IU/ml
Colorimetric - 450nm (TMB)
Cell Supernatant, Plasma, Serum
1 Plate/$528
F8 / FVIII / Factor VIII ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Mouse
0.5 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$805
Viewing 1-21 of 21 product results


Filtered By:
Products: ELISA Kits


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).