F12 / Factor XII

coagulation factor XII (Hageman factor)

F12 / Factor XII is coagulation factor XII which circulates in blood as a zymogen. This single chain zymogen is converted to a two-chain serine protease with an heavy chain (alpha-factor XIIa) and a light chain. The heavy chain contains two fibronectin-type domains, two epidermal growth factor (EGF)-like domains, a kringle domain and a proline-rich domain, whereas the light chain contains only a catalytic domain. On activation, further cleavages takes place in the heavy chain, resulting in the production of beta-factor XIIa light chain and the alpha-factor XIIa light chain becomes beta-factor XIIa heavy chain. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then to beta-factor XIIa. The active factor XIIa participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. It activates coagulation factors VII and XI. Defects in this gene do not cause any clinical symptoms and the sole effect is that whole-blood clotting time is prolonged.

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F12 / Factor XII (138)

Reactivity

Human (87)

Mouse (35)

Rat (10)

Chicken (2)

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IHC-plus™ F12 / Factor XII Antibody LS-B4239

(4.0) Rating

Antibody:

F12 / Factor XII Sheep anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

0.5 mg/$460

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F12 / Factor XII Antibody LS-C109227

Antibody:

F12 / Factor XII Sheep anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$334; 1 mg/$417; 10 mg/$2,196

• Unconjugated
• Unconjugated

• Unconjugated
• Unconjugated

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IHC-plus™ F12 / Factor XII Antibody LS-B2649

(4.0) Rating

Antibody:

F12 / Factor XII Goat anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

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IHC-plus™ F12 / Factor XII Antibody LS-B3044

(4.0) Rating

Antibody:

F12 / Factor XII Goat anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IE, IHC, IHC-P, IP

Format:

Unconjugated

Price:

50 µg/$460

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F12 / Factor XII Antibody LS-C150723

Antibody:

F12 / Factor XII Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Primate, Human

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

0.1 ml/$386

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F12 / Factor XII Antibody (N-Terminus) LS-C413031

Antibody:

F12 / Factor XII Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$299

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F12 / Factor XII Antibody LS-C23417

Antibody:

F12 / Factor XII Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, Func

Format:

Unconjugated

Price:

250 µg/$1,453

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F12 / Factor XII Antibody LS-C331638

Antibody:

F12 / Factor XII Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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Mouse F12 / Factor XII (Sandwich ELISA) ELISA Kit - LS-F10441

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.1 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma

Price:

1 Plate/$850

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Human F12 / Factor XII (Sandwich ELISA) ELISA Kit - LS-F10418

(4.1) Rating

(2) Publication(s)

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.5 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma

Price:

1 Plate/$530

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Mouse F12 / Factor XII (Sandwich ELISA) ELISA Kit - LS-F21335

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

0.16 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

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F12 / Factor XII Antibody (clone C6B7) LS-C83330

Antibody:

F12 / Factor XII Mouse anti-Human Monoclonal (C6B7) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

250 µg/$587

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Human F12 / Factor XII (Sandwich ELISA) ELISA Kit - LS-F4434

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

1.56 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma

Price:

1 Plate/$764

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F12 / Factor XII Antibody (clone 5B5) LS-C828162

Antibody:

F12 / Factor XII Mouse anti-Mouse Polyclonal (5B5) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$523; 1 mg/$3,293

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F12 / Factor XII Antibody LS-C147235

Antibody:

F12 / Factor XII Goat anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ID

Format:

Unconjugated

Price:

1 ml/$438

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F12 / Factor XII Antibody (clone B7C9) LS-C83329

Antibody:

F12 / Factor XII Mouse anti-Human Monoclonal (B7C9) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

250 µg/$587

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F12 / Factor XII Antibody (clone 3A3) LS-C197181

Antibody:

F12 / Factor XII Mouse anti-Human Monoclonal (3A3) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$423

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F12 / Factor XII Antibody LS-C128941

Antibody:

F12 / Factor XII Sheep anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

1 mg/$459

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F12 / Factor XII Antibody (aa73-372, clone OTI2D12) LS-C794012

Antibody:

F12 / Factor XII Mouse anti-Human Monoclonal (aa73-372) (OTI2D12) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$434

Select

F12 / Factor XII Antibody (aa73-372, clone OTI5A6) LS-C794013

Antibody:

F12 / Factor XII Mouse anti-Human Monoclonal (aa73-372) (OTI5A6) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$434

Select

F12 / Factor XII Antibody (aa9-38) LS-C159582

Antibody:

F12 / Factor XII Rabbit anti-Human Polyclonal (aa9-38) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

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F12 / Factor XII Antibody LS-C681904

Antibody:

F12 / Factor XII Rabbit anti-Pig Polyclonal Antibody

Reactivity:

Pig

Applications:

ELISA

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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F12 / Factor XII Antibody (aa400-615, Biotin) LS-C684873

Antibody:

F12 / Factor XII Rabbit anti-Human Polyclonal (aa400-615) (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$308; 200 µl/$350; 500 µl/$489; 1 ml/$558; 2 ml/$749; 5 ml/$1,217

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Rat F12 / Factor XII (Sandwich ELISA) ELISA Kit - LS-F15049

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

Select

Human F12 / Factor XII Protein (Over-Expression Cell Culture Supernatant His, N-Terminal) (Ile20-Ser615) - LS-G136059

Source:

HEK 293 Cells

Tag:

His, N-Terminal

Molecular Weight:

~66 kDa

Price:

200 µl/$283

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