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EWSR1 / EWS
EWS RNA-binding protein 1
EWSR1 / EWS is a multifunctional protein that is involved in various cellular processes, including gene expression, cell signaling, and RNA processing and transport. The protein includes an N-terminal transcriptional activation domain and a C-terminal RNA-binding domain. Chromosomal translocations between this gene and various genes encoding transcription factors result in the production of chimeric proteins that are involved in tumorigenesis. These chimeric proteins usually consist of the N-terminal transcriptional activation domain of this protein fused to the C-terminal DNA-binding domain of the transcription factor protein. Mutations in this gene, specifically a t(11;22)(q24;q12) translocation, are known to cause Ewing sarcoma as well as neuroectodermal and various other tumors. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and 14.
| Gene Name: | EWS RNA-binding protein 1 |
| Synonyms: | EWSR1, EWS, RNA-binding protein EWS, BK984G1.4, EWS oncogene |
| Target Sequences: | NM_005243 NP_005234.1 Q01844 |
Publications (1)
1
EWSR1::ATF1 Orchestrates the Clear Cell Sarcoma Transcriptome in Human Tumors and a Mouse Genetic Model. Benjamin B Ozenberger, Li Li, Emily R Wilson, Alexander J Lazar, Jared J Barrott, Kevin B Jones. Cancers. 2023 December;15: [Full Text Article]
[PubMed:38136296]
[PMC:PMC10742207]
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Antibodies
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EWSR1 / EWS
(74)
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(63)
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(27)
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(18)
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(35)
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(52)
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(74)
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(1)
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(1)
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(1)
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(7)
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(5)
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(1)
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(3)
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(2)
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(4)
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(2)
EWSR1 / EWS Mouse anti-Human Monoclonal (5C10) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
EWSR1 / EWS Rabbit anti-Human Polyclonal (aa369-399) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
EWSR1 / EWS Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
EWSR1 / EWS Goat anti-Human Polyclonal (aa201-215) Antibody
Mouse, Dog, Bovine, Rat, Hamster, Pig, Bat, Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
EWSR1 / EWS Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, IHC-P, IP, WB
Unconjugated
100 µl/$412
EWSR1 / EWS Mouse anti-Human Monoclonal (aa256-447) (OTI3F6) Antibody
Human
IF, IHC, WB
Unconjugated
100 µl/$434
EWSR1 / EWS Mouse anti-Human Monoclonal (aa256-447) (Carrier-free) (OTI3F6) Antibody
Human
IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
EWSR1 / EWS Rabbit anti-Human Polyclonal (aa628-656) Antibody
Human
Flo, IF, WB
Unconjugated
400 µl/$393
EWSR1 / EWS Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µg/$575
EWSR1 / EWS Mouse anti-Human Monoclonal (aa256-447) (OTI2B3) Antibody
Human
IHC, WB
Unconjugated
100 µl/$434
EWSR1 / EWS Mouse anti-Human Monoclonal (aa256-447) (Carrier-free) (OTI2B3) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
EWSR1 / EWS Mouse anti-Human Monoclonal (aa256-447) (OTI2D9) Antibody
Human
IHC, WB
Unconjugated
100 µl/$434
EWSR1 / EWS Mouse anti-Human Monoclonal (aa256-447) (Carrier-free) (OTI2D9) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
EWSR1 / EWS Mouse anti-Human Monoclonal (aa256-447) (OTI2G3) Antibody
Human
IHC, WB
Unconjugated
100 µl/$434
EWSR1 / EWS Mouse anti-Human Monoclonal (aa256-447) (Carrier-free) (OTI2G3) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
EWSR1 / EWS Mouse anti-Human Monoclonal (5H7) Antibody
Human
ICC, IF, WB
Unconjugated
100 µl/$376
EWSR1 / EWS Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
EWSR1 / EWS Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
EWSR1 / EWS Rabbit anti-Human Polyclonal (aa100-150) Antibody
Mouse, Human
IHC, IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
EWSR1 / EWS Rabbit anti-Human Polyclonal (aa1-300) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
EWSR1 / EWS Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
EWSR1 / EWS Rabbit anti-Human Polyclonal (aa623-652) Antibody
Human
IF, WB
Unconjugated
400 µl/$393
EWSR1 / EWS Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
EWSR1 / EWS Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$341
EWSR1 / EWS Rabbit anti-Human Polyclonal (aa628-656) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
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