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EPCAM

epithelial cell adhesion molecule

May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E.

Gene Name: epithelial cell adhesion molecule
Synonyms: EPCAM, 323/A3, ACSTD1, 17-1A, CD326, EGP, EGP34, Epithelial glycoprotein, GA733-2, HNPCC8, Ep-CAM, ESA, HEGP314, KS 1/4 antigen, KS1/4, KSA, M1S2, MIC18, MK-1, MH99, TROP1, TACST-1, TACSTD1, CD326 antigen, CO-17A, DIAR5, EGP-2, EGP314, EGP40, Epithelial glycoprotein 314, HEA125, Ly74, M4S1
Target Sequences: NM_002354 NP_002345.2 P16422

Publications (5)

1
Nuclear signalling by tumour-associated antigen EpCAM. Maetzel D, Denzel S, Mack B, Canis M, Went P, Benk M, Kieu C, Papior P, Baeuerle PA, Munz M, Gires O. Nature cell biology. 2009 11:162-71. (IP) [PubMed:19136966]
2
Both human and mouse mesenchymal stem cells promote breast cancer metastasis. Albarenque SM, Zwacka RM, Mohr A. Stem cell research. 2011 7:163-71. [PubMed:21763624]
3
An improved method for isolation of epithelial and stromal cells from the human endometrium. Masuda A, Katoh N, Nakabayashi K, Kato K, Sonoda K, Kitade M, Takeda S, Hata K, Tomikawa J. The Journal of reproduction and development. 2016 62:213-8. (Flo; Human) [Full Text Article] [PubMed:26853786] [PMC:PMC4848580] Related Antibodies: LS-C112552.
4
A role for intestinal TLR4-driven inflammatory response during activity-based anorexia. Belmonte L, Achamrah N, Nobis S, Guérin C, Riou G, Bôle-Feysot C, Boyer O, Richard V, Rego JC, Déchelotte P, Goichon A, Coëffier M. Scientific reports. 2016 October;6:35813. (Mouse) [Full Text Article] [PubMed:27779218] [PMC:PMC5078809]
5
Characterization of preneoplastic and neoplastic rat mesothelial cell lines: the involvement of TETs, DNMTs, and 5-hydroxymethylcytosine. Roulois D, Deshayes S, Guilly MN, Nader JS, Liddell C, Robard M, Hulin P, Ouacher A, Le Martelot V, Fonteneau JF, Grégoire M, Blanquart C, Pouliquen DL. Oncotarget. 2016 June;7:34664-87. (Human) [Full Text Article] [PubMed:27129173] [PMC:PMC5085183] Related Antibodies: LS-C331328.
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Antibodies (284)
Primary (284)
EPCAM (284)
Human (242)
Mouse (32)
Rat (16)
Chicken (8)
Cynomolgus (1)
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IHC (107)
IHC-Fr (26)
IHC-P (106)
WB (200)
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rabbit (98)
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monoclonal mc (178)
polyclonal pc (88)
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06 (1)
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EPCAM Antibody - Anti-EPCAM antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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EPCAM Mouse anti-Human Monoclonal (VU-1D9) Antibody
Human
Flo, ICC, IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated
0.05 mg/$460
EPCAM Antibody - Surface staining of human MCF-7 cell line with anti-human CD326 / EpCAM (VU-1D9) PE.
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EPCAM Mouse anti-Human Monoclonal (PE) (VU-1D9) Antibody
Human
Flo, IHC-Fr
PE Conjugated
100 Tests/$365
EPCAM Antibody - Surface staining of human MCF-7 cell line with anti-human CD326 / EpCAM (VU-1D9) APC.
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EPCAM Mouse anti-Human Monoclonal (APC) (VU-1D9) Antibody
Human
Flo, ICC, IHC-Fr, IHC-P, IP, WB
APC Conjugated
100 Tests/$365
EPCAM Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Cancer Pathology
Cancer
EPCAM Rabbit anti-Human Recombinant Monoclonal (EGP40/1556R) Antibody
Human
Flo, IF, IHC-P
Unconjugated
100 µg/$525
EPCAM Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
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EPCAM Rabbit anti-Mouse Polyclonal (aa217-251) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
200 µl/$460
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EPCAM Rat anti-Mouse Monoclonal (G8.8) Antibody
Mouse
Flo, ICC, IHC, IHC-Fr, IP, WB
Unconjugated
0.1 mg/$424
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EPCAM Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
100 µg/$634
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EPCAM Rabbit anti-Human Polyclonal (aa57-85) (Biotin) Antibody
Human
ELISA, Flo, WB
Biotin Conjugated
200 µl/$952
EPCAM Antibody - Formalin-fixed, paraffin-embedded human ovarian carcinoma stained with EpCAM antibody (EGP40/1110).  This image was taken for the unmodified form of this product. Other forms have not been tested.
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EPCAM Mouse anti-Human Monoclonal (Cytoplasmic Domain) (EGP40/1110) Antibody
Mouse, Rat, Human
IHC-P
Unconjugated
20 µg/$371; 100 µg/$574
EPCAM Antibody - Western blot of recombinant TACSTD1 / EPCAM with EPCAM antibody
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EPCAM Rabbit anti-Pig Polyclonal (aa25-265) Antibody
Pig
WB
Unconjugated
100 µl/$322; 200 µl/$370; 500 µl/$529; 1 ml/$614; 2 ml/$846; 5 ml/$1,393
EPCAM Antibody - Western blot of recombinant TACSTD1 / EPCAM with EPCAM antibody
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EPCAM Rabbit anti-Pig Polyclonal (aa25-265) (FITC) Antibody
Pig
WB
FITC Conjugated
100 µl/$367; 200 µl/$433; 500 µl/$686; 1 ml/$846; 2 ml/$1,092; 5 ml/$1,951
EPCAM Antibody - Western blot of recombinant TACSTD1 / EPCAM with EPCAM antibody
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EPCAM Rabbit anti-Pig Polyclonal (aa25-265) (Cy3) Antibody
Pig
WB
Cy3 Conjugated
100 µl/$434; 200 µl/$529; 500 µl/$938; 1 ml/$1,108; 2 ml/$1,487; 5 ml/$2,787
EPCAM Antibody - Anti-EPCAM antibody IHC of human intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
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EPCAM Mouse anti-Human Monoclonal (Concentrated) (VU-1D9) Antibody
Human
ELISA, Flo, IHC, IHC-P, WB
Unconjugated, Concentrated
50 µl/$495
EPCAM Antibody - Anti-ESA / EPCAM antibody IHC staining of human uterus, endometrium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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EPCAM Mouse anti-Human Monoclonal (HEA-125) Antibody
Human
Flo, IF, IHC, IHC-Fr, IHC-P
Unconjugated
50 µg/$485
EPCAM Antibody - Anti-EPCAM antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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EPCAM Mouse anti-Human Monoclonal (VU-1D9) Antibody
Human
Flo, IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated
0.1 mg/$460
EPCAM Antibody - Anti-EPCAM antibody IHC of human uterus, endometrium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
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Cancer Pathology
Cancer
EPCAM Mouse anti-Human Monoclonal (Concentrated) (MOC-31) Antibody
Human
IHC, IHC-Fr, IHC-P, WB
Unconjugated, Concentrated
0.1 ml/$460
EPCAM Antibody - Anti-EPCAM antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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EPCAM Mouse anti-Human Monoclonal (VU1D9 ) Antibody
Human
Flo, ICC, IHC, IHC-Fr, IHC-P, WB
Unconjugated
50 µg/$440
EPCAM Antibody - EpCAM Antibody western blot of 293 cell line lysates (35 ug/lane). The EpCAM antibody detected the EpCAM protein (arrow).
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EPCAM Rabbit anti-Human Polyclonal (aa57-85) Antibody
Human
Flo, WB
Unconjugated
400 µl/$393
EPCAM Antibody - Immunohistochemistry of paraffin-embedded human lung cancer using EPCAM antibodyat dilution of 1:100 (40x lens).
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EPCAM Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
EPCAM Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
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EPCAM Mouse anti-Human Monoclonal (aa27-59) (VU-1D9) Antibody
Human
Flo, IHC, IHC-P
Unconjugated
250 µl/$460
EPCAM Antibody - IHC of paraffin-embedded Human colon tissue using anti-EPCAM mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).
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EPCAM Mouse anti-Human Monoclonal (OTI1H9) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
EPCAM Antibody - Western blot of TACSTD1 / EPCAM antibody.
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EPCAM Rabbit anti-Chicken Polyclonal (aa21-260) (APC) Antibody
Chicken
WB
APC Conjugated
100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521
Select
EPCAM Mouse anti-Human Monoclonal (HEA125) Antibody
Human
ELISA, Flo, IF, IHC-Fr, IHC-P
Unconjugated
0.1 mg/$424
EPCAM Antibody - HT-29 cells stained with Mouse anti Human CD326: Endotoxin Low. This image was taken for the unmodified form of this product. Other forms have not been tested.
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EPCAM Mouse anti-Human Monoclonal (Low Endotoxin) (VU-1D9) Antibody
Human
Flo, IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated, Low Endotoxin
0.5 mg/$671
Select
EPCAM Mouse anti-Human Monoclonal (323/A3) Antibody
Mouse, Human
Flo, ICC, IHC-P, IP, WB
Unconjugated
100 µg/$372
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).