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EFNB2 / Ephrin B2

ephrin-B2

Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to receptor tyrosine kinase including EPHA4, EPHA3 and EPHB4. Together with EPHB4 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation from EFNB2-expressing cells. May play a role in constraining the orientation of longitudinally projecting axons.

Gene Name: ephrin-B2
Family/Subfamily: Ephrin , Not assigned-Other
Synonyms: EFNB2, Ephrin-B2, EPLG5, Ephrin B2, HTK ligand, Htk-L, LERK-5, LERK5, Ligand of eph-related kinase 5, HTKL
Target Sequences: NM_004093 NP_004084.1 P52799

Publications (1)

1
The differential expression of EPHB4 and ephrin B2 in cutaneous squamous cell carcinoma according to the grade of tumor differentiation: a clinicopathological study. Shin Taek Oh, Keum Jin Yang, Jung Min Bae, Hyun Jeong Park, Dong Soo Yoo, Young Min Park. International journal of dermatology. 2021 June;60:736-741. [Full Text Article] [PubMed:33598934] Related Antibodies: LS-C403980.

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Antibodies (28)
Primary (28)
EFNB2 / Ephrin B2 (28)
Human (24)
Mouse (14)
Rat (9)
Bovine (3)
Chicken (3)
Dog (3)
Hamster (1)
Horse (3)
Monkey (3)
Pig (3)
Rabbit (2)
Xenopus (2)
IHC (9)
IHC-P (5)
WB (20)
ELISA (11)
IF (3)
Peptide-ELISA (3)
rabbit (27)
goat (1)
Product Group
PathPlus Neuro (2)
IgG (10)
polyclonal pc (28)
APC (1)
APC Conjugated (1)
Biotin Conjugated (1)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
PE Conjugated (1)
Preservative Free (1)
Unconjugated (21)
aa42-333 (8)
aa28-229 (2)
aa157-186 (1)
aa31-225 (1)
aa62-74 (1)
pTyr330 (1)
No (27)
Yes (1)
EFNB2 / Ephrin B2 Antibody - Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Neuroscience
EFNB2 / Ephrin B2 Goat anti-Human Polyclonal (aa62-74) Antibody
Chicken, Bovine, Rat, Hamster, Pig, Horse, Mouse, Dog, Human, Monkey
IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$460
EFNB2 / Ephrin B2 Antibody - Immunohistochemistry of paraffin-embedded Human esophagus cancer using EFNB2 Polyclonal Antibody at dilution of 1:80.
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EFNB2 / Ephrin B2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
EFNB2 / Ephrin B2 Antibody - Anti-EFNB2 / Ephrin B2 antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
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Neuroscience
EFNB2 / Ephrin B2 Rabbit anti-Human Polyclonal (aa157-186) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
200 µl/$440
EFNB2 / Ephrin B2 Antibody - Immunohistochemistry of paraffin-embedded human skin using antibody at 1:100 dilution.
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EFNB2 / Ephrin B2 Rabbit anti-Human Polyclonal (aa28-229) Antibody
Mouse, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
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EFNB2 / Ephrin B2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$357
EFNB2 / Ephrin B2 Antibody - Immunohistochemistry of paraffin-embedded rat brain tissue.
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EFNB2 / Ephrin B2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
EFNB2 / Ephrin B2 Antibody - 1:100 staining rat testis tissue by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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EFNB2 / Ephrin B2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
EFNB2 / Ephrin B2 Antibody - Immunohistochemistry of paraffin-embedded human skin using antibody at 1:100 dilution.
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EFNB2 / Ephrin B2 Rabbit anti-Human Polyclonal (aa28-229) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
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EFNB2 / Ephrin B2 Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, IHC, IHC-P
Unconjugated
100 µl/$412
EFNB2 / Ephrin B2 Antibody
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EFNB2 / Ephrin B2 Rabbit anti-Human Polyclonal (aa31-225) Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µl/$332
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EFNB2 / Ephrin B2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µl/$356; 100 µl/$461
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EFNB2 / Ephrin B2 Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA
Unconjugated
100 µl/$412
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EFNB2 / Ephrin B2 Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA
Unconjugated
100 µl/$412
EFNB2 / Ephrin B2 Antibody - Western blot analysis of Phospho-EFNB1/2 (Tyr330) expression in various lysates
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EFNB2 / Ephrin B2 Rabbit anti-Human Polyclonal (pTyr330) Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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EFNB2 / Ephrin B2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
100 µl/$412
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EFNB2 / Ephrin B2 Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
ELISA
Unconjugated, Preservative Free
100 µl/$412
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EFNB2 / Ephrin B2 Rabbit anti-Human Polyclonal Antibody
Xenopus, Chicken, Bovine, Rabbit, Mouse, Dog, Rat, Pig, Horse, Human, Monkey
WB
Unconjugated
50 µg/$489
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EFNB2 / Ephrin B2 Rabbit anti-Human Polyclonal Antibody
Xenopus, Chicken, Bovine, Rabbit, Mouse, Dog, Rat, Pig, Horse, Human, Monkey
WB
Unconjugated
50 µg/$489
EFNB2 / Ephrin B2 Antibody - Western blot of recombinant EFNB2 / Ephrin B2.
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EFNB2 / Ephrin B2 Rabbit anti-Human Polyclonal (aa42-333) Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
EFNB2 / Ephrin B2 Antibody - Western blot of recombinant EFNB2 / Ephrin B2.
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EFNB2 / Ephrin B2 Rabbit anti-Human Polyclonal (aa42-333) (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$338; 200 µl/$393; 500 µl/$575; 1 ml/$702; 2 ml/$939; 5 ml/$1,593
EFNB2 / Ephrin B2 Antibody - Western blot of recombinant EFNB2 / Ephrin B2.
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EFNB2 / Ephrin B2 Rabbit anti-Human Polyclonal (aa42-333) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$596; 2 ml/$824; 5 ml/$1,348
EFNB2 / Ephrin B2 Antibody - Western blot of recombinant EFNB2 / Ephrin B2.
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EFNB2 / Ephrin B2 Rabbit anti-Human Polyclonal (aa42-333) (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$348; 200 µl/$407; 500 µl/$605; 1 ml/$755; 2 ml/$993; 5 ml/$1,716
EFNB2 / Ephrin B2 Antibody - Western blot of recombinant EFNB2 / Ephrin B2.
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EFNB2 / Ephrin B2 Rabbit anti-Human Polyclonal (aa42-333) (Cy3) Antibody
Human
WB
Cy3 Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
EFNB2 / Ephrin B2 Antibody - Western blot analysis of extracts of various cell lines, using EFNB2 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 90s.
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EFNB2 / Ephrin B2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
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EFNB2 / Ephrin B2 Rabbit anti-Rat Polyclonal Antibody
Rat
ELISA
Unconjugated
100 µl/$412
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).