DUT / DUTPase

deoxyuridine triphosphatase

DUT / DUTPase is an essential enzyme of nucleotide metabolism. The encoded protein forms a ubiquitous, homotetrameric enzyme that hydrolyzes dUTP to dUMP and pyrophosphate. This reaction serves two cellular purposes: providing a precursor (dUMP) for the synthesis of thymine nucleotides needed for DNA replication, and limiting intracellular pools of dUTP. Elevated levels of dUTP lead to increased incorporation of uracil into DNA, which induces extensive excision repair mediated by uracil glycosylase. This repair process, resulting in the removal and reincorporation of dUTP, is self-defeating and leads to DNA fragmentation and cell death. Alternative splicing of this gene leads to different isoforms that localize to either the mitochondrion or nucleus. A related pseudogene is located on chromosome 19.

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Products

Antibodies (44)

Proteins (14)

ELISA Kits (3)

Type

Custom (1)

Over-Expression Lysate (4)

Primary (44)

Recombinant (10)

Sandwich (2)

Target

DUT / DUTPase (61)

Reactivity

Human (46)

Mouse (10)

Rat (13)

Bat (3)

Dog (3)

Gibbon (3)

Guinea pig (3)

Horse (3)

Monkey (2)

Sheep (1)

Yeast (3)

Zebrafish (3)

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Application

IHC (30)

IHC-P (13)

WB (39)

ELISA (14)

IF (2)

IP (4)

Peptide-ELISA (1)

Host

rabbit (41)

mouse (1)

goat (1)

chicken (1)

Product Group

IHCPlus (3)

Isotype

IgG (30)

IgG1,k (1)

IgY (1)

Clonality

monoclonal mc (1)

polyclonal pc (43)

Clone

1C9 (1)

Format

96-Well Strip Plate (3)

APC Conjugated (2)

Azide-free (1)

Biotin Conjugated (4)

FITC Conjugated (4)

HRP Conjugated (4)

Magnetic beads Conjugated (1)

PE Conjugated (2)

Sepharose Conjugated (1)

Unconjugated (26)

Epitope

aa170-198 (7)

C-Terminus (4)

aa35-84 (4)

Internal (3)

aa136-150 (2)

aa25-44 (2)

aa1-52 (1)

Publications

No (61)

Sample Type

Plasma (2)

Serum (2)

Tissue Homogenates (1)

Tag

6His, N-terminus (2)

GST (1)

GST, N-terminus (2)

His (1)

Myc-DDK (Flag) (6)

Species

Human (12)

Source

293T Cells (2)

E. coli (5)

HEK 293 Cells (4)

Wheat Germ Extract (3)

Purification

Purified (4)

Low Endotoxin Level

Low endotoxin level (4)

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IHC-plus™ DUT / DUTPase Antibody (clone 1C9) LS-B4315

(4.0) Rating

Antibody:

DUT / DUTPase Mouse anti-Human Monoclonal (1C9) Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

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DUT / DUTPase Antibody (C-Terminus) LS-C80791

Antibody:

DUT / DUTPase Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$397

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DUT / DUTPase Antibody (aa136-150) LS-C312268

Antibody:

DUT / DUTPase Rabbit anti-Human Polyclonal (aa136-150) Antibody

Reactivity:

Mouse, Sheep, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

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DUT / DUTPase Antibody (aa25-44) LS-C673

Antibody:

DUT / DUTPase Rabbit anti-Human Polyclonal (aa25-44) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

200 µl/$386

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IHC-plus™ DUT / DUTPase Antibody (aa1-52) LS-B737

(4.0) Rating

Antibody:

DUT / DUTPase Chicken anti-Human Polyclonal (aa1-52) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$485

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IHC-plus™ DUT / DUTPase Antibody LS-B15954

(4.0) Rating

Antibody:

DUT / DUTPase Goat anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µg/$460

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DUT / DUTPase Antibody LS-C834144

Antibody:

DUT / DUTPase Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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DUT / DUTPase Antibody LS-C121723

Antibody:

DUT / DUTPase Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

100 µg/$564

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DUT / DUTPase Antibody (aa170-198) LS-C320978

Antibody:

DUT / DUTPase Rabbit anti-Human Polyclonal (aa170-198) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

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DUT / DUTPase Antibody (aa170-198, Biotin) LS-C222301

Antibody:

DUT / DUTPase Rabbit anti-Human Polyclonal (aa170-198) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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DUT / DUTPase Antibody (aa170-198, FITC) LS-C222300

Antibody:

DUT / DUTPase Rabbit anti-Human Polyclonal (aa170-198) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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DUT / DUTPase Antibody (aa170-198, APC) LS-C222299

Antibody:

DUT / DUTPase Rabbit anti-Human Polyclonal (aa170-198) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

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DUT / DUTPase Antibody (aa170-198, Azide-free, HRP) LS-C222302

Antibody:

DUT / DUTPase Rabbit anti-Human Polyclonal (aa170-198) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

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DUT / DUTPase Antibody (aa170-198, PE) LS-C222305

Antibody:

DUT / DUTPase Rabbit anti-Human Polyclonal (aa170-198) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

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DUT / DUTPase Antibody LS-C750929

Antibody:

DUT / DUTPase Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$466

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DUT / DUTPase Antibody LS-C750927

Antibody:

DUT / DUTPase Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$466

Select

DUT / DUTPase Antibody LS-C750928

Antibody:

DUT / DUTPase Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$466

Select

DUT / DUTPase Antibody LS-C402243

Antibody:

DUT / DUTPase Rabbit anti-Human Polyclonal Antibody

Reactivity:

Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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DUT / DUTPase Antibody (aa136-150) LS-C121724

Antibody:

DUT / DUTPase Rabbit anti-Human Polyclonal (aa136-150) Antibody

Reactivity:

Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$614

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DUT / DUTPase Antibody (Internal) LS-C171555

Antibody:

DUT / DUTPase Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$380

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DUT / DUTPase Antibody (aa170-198) LS-C167581

Antibody:

DUT / DUTPase Rabbit anti-Human Polyclonal (aa170-198) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

Select

DUT / DUTPase Antibody LS-C341760

Antibody:

DUT / DUTPase Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

50 µl/$356; 100 µl/$461

Select

DUT / DUTPase Antibody LS-C830746

Antibody:

DUT / DUTPase Rabbit anti-Human Polyclonal Antibody

Reactivity:

Rat, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

DUT / DUTPase Antibody LS-C832256

Antibody:

DUT / DUTPase Rabbit anti-Human Polyclonal Antibody

Reactivity:

Rat, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

DUT / DUTPase Antibody LS-C332280

Antibody:

DUT / DUTPase Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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