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DRD4 / Dopamine Receptor D4

dopamine receptor D4

Dopamine Receptor D4 (DRD4), a Dopamine Receptor, has been suggested to affect personality, substance dependence, cognition, and emotion. DRD4 binds the antipsychotic medications clozapine and spiperone. DRD4 knock-out mice are anatomically normal but display altered locomotion and sensitivity to drugs such as clozapine, cocaine, and others. The DRD4 gene contains extensive polymorphisms consisting of variable numbers of tandem repeats (VNTR) in sequences corresponding to the third cytoplasmic loop of the receptor; at least 27 different haplotypes encoding 20 different protein variants have been documented. The frequency of the different variants varies among population groups. Studies have suggested a link between VNTR and human personality traits (such as novelty seeking) and diseases (such as schizophrenia, bipolar affective disorder, and Tourette syndrome); however, considerable debates exist regarding the validity and significance of such associations.

Gene Name: dopamine receptor D4
Family/Subfamily: GPCR , Dopamine
Synonyms: DRD4, D(4) dopamine receptor, D4DR
Target Sequences: NM_000797 NP_000788.2 P21917

☰ Filters
Antibodies (41)
ELISA Kits (11)
Primary (41)
Sandwich (10)
Sandwich CLIA (1)
DRD4 / Dopamine Receptor D4 (52)
Human (39)
Mouse (32)
Rat (19)
Bovine (1)
Chicken (1)
Dog (1)
Monkey (3)
Porcine (1)
Rabbit (1)
Sheep (1)
IHC (6)
IHC-P (2)
WB (39)
Flo (1)
ELISA (21)
ICC (8)
IF (5)
Peptide-ELISA (4)
rabbit (27)
mouse (13)
goat (1)
Product Group
GPCR Database Antibodies (1)
PathPlus Neuro (1)
IgG (21)
IgG1 (7)
IgG1,k (6)
monoclonal mc (13)
polyclonal pc (28)
625CT1.5.4 (6)
GF1 (1)
12 x 8-Well Microstrips (1)
96-Well Microplate (1)
96-Well Strip Plate (9)
APC Conjugated (3)
Azide-free (2)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (3)
Unconjugated (26)
aa365-391 (14)
C-Terminus (2)
N-Terminus (2)
330-410 aa, C-terminal (1)
3rd Extracellular Domain (1)
Leu396 (1)
aa140-152 (1)
aa176-185 (1)
aa347-396 (1)
aa355-404 (1)
No (51)
Yes (1)
Cell Lysates (1)
Plasma (5)
Serum (5)
Tissue Homogenates (2)
DRD4 / Dopamine Receptor D4 Antibody - Anti-DRD4 / Dopamine Receptor D4 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Neuroscience
Fast Shipping
DRD4 / Dopamine Receptor D4 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$440
Select
DRD4 / Dopamine Receptor D4 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
ELISA, WB
Unconjugated
100 µl/$801
Select
DRD4 / Dopamine Receptor D4 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$832
DRD4 / Dopamine Receptor D4 Antibody - Formalin-fixed and paraffin-embedded human brain tissue reacted with DRD4 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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DRD4 / Dopamine Receptor D4 Rabbit anti-Human Polyclonal (aa365-391) Antibody
Mouse, Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
DRD4 / Dopamine Receptor D4 Antibody - Immunohistochemistry of paraffin-embedded Human lung cancer using DRD4 Polyclonal Antibody at dilution of 1:30.
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DRD4 / Dopamine Receptor D4 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
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DRD4 / Dopamine Receptor D4 Rabbit anti-Rat Polyclonal (aa176-185) Antibody
Rat
ELISA, IHC, WB
Unconjugated
100 µl/$775
DRD4 / Dopamine Receptor D4 Antibody - DRD4 Antibody western blot of mouse heart tissue lysates (35 ug/lane). The DRD4 antibody detected the DRD4 protein (arrow).
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DRD4 / Dopamine Receptor D4 Mouse anti-Human Monoclonal (aa365-391) Antibody
Mouse, Human
WB
Unconjugated
400 µl/$393
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DRD4 / Dopamine Receptor D4 Goat anti-Human Polyclonal (aa140-152) Antibody
Human, Monkey
Peptide-ELISA
Unconjugated
100 µg/$384
DRD4 / Dopamine Receptor D4 ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$715
DRD4 / Dopamine Receptor D4 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
DRD4 / Dopamine Receptor D4 Antibody - Immunohistochemistry of paraffin-embedded human cervical cancer tissue using DRD4 antibody.
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DRD4 / Dopamine Receptor D4 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
DRD4 / Dopamine Receptor D4 Antibody - Staining MCF-7 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
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DRD4 / Dopamine Receptor D4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
DRD4 / Dopamine Receptor D4 Antibody - Western blot of D4DR antibody
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DRD4 / Dopamine Receptor D4 Rabbit anti-Human Polyclonal (330-410 aa, C-terminal) Antibody
Mouse, Rat, Human
ELISA, IF, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
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DRD4 / Dopamine Receptor D4 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, ICC, WB
Unconjugated
50 µl/$717
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DRD4 / Dopamine Receptor D4 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, ICC, WB
Unconjugated
5 ml/$538
DRD4 / Dopamine Receptor D4 Antibody - Peptide - + Immunofluorescence analysis of MCF-7 cells, using DRD4 antibody.
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DRD4 / Dopamine Receptor D4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, WB
Unconjugated
100 µg/$357
DRD4 / Dopamine Receptor D4 Antibody - Immunofluorescence analysis of MCF7 cells, using DRD4 Antibody. The picture on the right is blocked with the synthesized peptide.
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DRD4 / Dopamine Receptor D4 Rabbit anti-Human Polyclonal (aa355-404) Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
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DRD4 / Dopamine Receptor D4 Mouse anti-Human Monoclonal (GF1) Antibody
Mouse, Rat, Human
ICC, WB
Unconjugated
100 µg/$854
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DRD4 / Dopamine Receptor D4 Mouse anti-Human Monoclonal (FITC) Antibody
Mouse, Rat, Human
ICC, WB
FITC Conjugated
100 µl/$1,073
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DRD4 / Dopamine Receptor D4 Mouse anti-Human Monoclonal (APC) Antibody
Mouse, Rat, Human
ICC, WB
APC Conjugated
100 µl/$1,073
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DRD4 / Dopamine Receptor D4 Rabbit anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
50 µl/$356; 100 µl/$461
DRD4 / Dopamine Receptor D4 Antibody - Western blot of D4DR (L396) pAb in extracts from HeLa cells.
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DRD4 / Dopamine Receptor D4 Rabbit anti-Human Polyclonal (Leu396) Antibody
Mouse, Rat, Human
IF, WB
Unconjugated
50 µl/$321; 100 µl/$403
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DRD4 / Dopamine Receptor D4 Rabbit anti-Mouse Polyclonal (3rd Extracellular Domain) Antibody
Mouse
ELISA, WB
Unconjugated
50 µg/$821
Select
DRD4 / Dopamine Receptor D4 Mouse anti-Human Monoclonal (aa365-391) (625CT1.5.4) Antibody
Mouse, Human
ELISA, WB
Unconjugated
200 µl/$734
Select
DRD4 / Dopamine Receptor D4 Rabbit anti-Human Polyclonal (aa365-391) Antibody
Mouse, Human
ELISA, WB
Unconjugated
200 µl/$734
Viewing 1-25 of 52 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).