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Catalog Number	Size	Price
LS-A3921-50	50 µg (1 mg/ml)	$440

DRD4 / Dopamine Receptor D4 Antibody - Anti-DRD4 / Dopamine Receptor D4 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

DRD4 / Dopamine Receptor D4 Antibody - Brain, Hippocampus, dentate gyrus

DRD4 / Dopamine Receptor D4 Antibody - Anti-DRD4 / Dopamine Receptor D4 antibody IHC of human Lung, Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

DRD4 / Dopamine Receptor D4 Antibody - Anti-DRD4 / Dopamine Receptor D4 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

DRD4 / Dopamine Receptor D4 Antibody - Anti-DRD4 / Dopamine Receptor D4 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

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PathPlus™ Polyclonal Rabbit anti‑Human DRD4 / Dopamine Receptor D4 Antibody (C‑Terminus, IHC) LS‑A3921

Name: PathPlus™ DRD4 / Dopamine Receptor D4 Polyclonal Antibody Rabbit | LSBio
Brand: Lifespan BioSciences
SKU: LS-A3921-50
Price: 440.0000 USD
Availability: InStock
Rating: 5 (1 reviews)

Neuroscience

(5.0) Rating

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Note: This antibody replaces LS-C64988

Antibody:

DRD4 / Dopamine Receptor D4 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Application:

IHC, IHC-P

Reactivity:

Human, Monkey

Format:

Unconjugated, Unmodified

$440

LS-A3921-50

Ready To Ship

Toll Free North America

(800) 227-6666

For Research Use Only

Specifications Validation Publications Reviews Featured Products Request SDS/MSDS

Overview

Antibody:

DRD4 / Dopamine Receptor D4 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Application:

IHC, IHC-P

Reactivity:

Human, Monkey

Format:

Unconjugated, Unmodified

Specifications

Description

Dopamine Receptor D4 (DRD4) has been suggested to affect personality, substance dependence, cognition, and emotion. DRD4 binds the antipsychotic medications clozapine and spiperone. The DRD4 gene contains extensive polymorphisms consisting of variable numbers of tandem repeats (VNTR) in sequences corresponding to the third cytoplasmic loop of the receptor; at least 27 different haplotypes encoding 20 different protein variants have been documented. The frequency of the different variants varies among population groups. Studies have suggested a link between VNTR and human personality traits (such as novelty seeking) and diseases (such as schizophrenia, bipolar affective disorder, and Tourette syndrome); however, considerable debates exist regarding the validity and significance of such associations. References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804

Target

Human DRD4 / Dopamine Receptor D4

Synonyms

DRD4 | D(4) dopamine receptor | D4DR

See All DRD4 / Dopamine Receptor D4 Antibodies

Host

Rabbit

Reactivity

Human, Monkey (tested or 100% immunogen sequence identity)

Clonality

Polyclonal

Conjugations

Unconjugated

Purification

Immunoaffinity purified

Modifications

Unmodified

Immunogen

Synthetic 17 amino acid peptide from C-Terminus of human DRD4 / Dopamine Receptor D4. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset (100%); Ferret, Panda (88%); Hamster, Elephant, Horse, Pig (82%).

Epitope

C-Terminus

Specificity

Human DRD4 / Dopamine Receptor D4. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except HTR1D (65%).

Applications

IHC
IHC - Paraffin (5 - 10 µg/ml)

Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.

Presentation

PBS, 0.1% Sodium Azide

Storage

Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.

Restrictions

For research use only. Intended for use by laboratory professionals.

Guarantee

This antibody carries the LSBio 100% Guarantee.

LSBio Guarantee

About DRD4 / Dopamine Receptor D4

Uniprot: P21917 NCBI: NM_000797 NP_000788.2

Validation

Anti-DRD4 / Dopamine Receptor D4 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Brain, Hippocampus, dentate gyrus

Anti-DRD4 / Dopamine Receptor D4 antibody IHC of human Lung, Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-DRD4 / Dopamine Receptor D4 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-DRD4 / Dopamine Receptor D4 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

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PathPlus™ Validation Process