DKK1

dickkopf WNT signaling pathway inhibitor 1

Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.

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Products

Proteins (21)

Type

Over-Expression Lysate (2)

Recombinant (19)

Target

DKK1 (21)

Publications

No (21)

Tag

6His, C-terminus (1)

6His, N-terminus (2)

8His, N-terminus (1)

AVI-6His, C-terminus (1)

DDK,C-terminus (1)

Fc, C-terminus (1)

GST (1)

GST, N-terminus (1)

His (3)

His, N-Terminal (1)

His,C-terminus (1)

His,N-terminus (1)

His-GST (1)

His-GST, N-terminus (1)

Myc-DDK (Flag) (2)

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Species

Human (17)

Mouse (1)

Rat (1)

Source

293T Cells (1)

Baculovirus (1)

CHO Cells (1)

E. coli (7)

HEK 293 Cells (4)

Human (2)

Human Cells (1)

Mammalian Cells (1)

Sf9 Cells (1)

Wheat Germ Extract (2)

Purification

Purified (7)

Low Endotoxin Level

Low endotoxin level (9)

Biologically Active

Biologically active (3)

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Human DKK1 Protein (Recombinant 6His, N-terminus) (aa33-266) - LS-G64227

Source:

E. coli

Tag:

6His, N-terminus

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human DKK1 Protein (Recombinant) - LS-G105

Source:

HEK 293 Cells

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.1 ng/µg of protein (less than 1EU/µg).

Molecular Weight:

35-40 kDa

Price:

2 µg/$268; 10 µg/$349

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Human DKK1 Protein (Recombinant His,N-terminus) (Thr32-His266) - LS-G140576

Source:

Mammalian Cells

Tag:

His,N-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

27 kDa

Price:

10 µg/$317; 50 µg/$524

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Human DKK1 Protein (Recombinant His,C-terminus) (Met2-His266) - LS-G138381

Source:

HEK 293 Cells

Tag:

His,C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

25.8 kDa

Price:

20 µg/$392; 100 µg/$626

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Human DKK1 Protein (Recombinant 6His, C-terminus) (Thr32-His266) - LS-G145588

Source:

HEK 293 Cells

Tag:

6His, C-terminus

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.2 EU/µg protein (determined by LAL method).

Molecular Weight:

38-40 kDa

Price:

10 µg/$257; 1 mg/$1,871; 50 µg/$355

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Human DKK1 Protein (Recombinant Fc, C-terminus) - LS-G146161

Source:

Human

Tag:

Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

52.7 kDa

Price:

10 µg/$271; 50 µg/$391

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Human DKK1 Protein (Recombinant AVI-6His, C-terminus) - LS-G146181

Source:

Human

Tag:

AVI-6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

28.4 kDa

Price:

20 µg/$416; 100 µg/$910

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Human DKK1 Protein (Recombinant His, N-Terminal) - LS-G133748

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

33kDa

Price:

10 µg/$337; 50 µg/$792; 200 µg/$1,419; 100 µg/$1,203; 1 mg/$2,715; 500 µg/$2,211; 5 mg/$5,545; 2 mg/$2,957

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Mouse DKK1 Protein (Recombinant His-GST, N-terminus) (Val36-Ala260) - LS-G132605

Source:

E. coli

Tag:

His-GST, N-terminus

Molecular Weight:

54.3kDa

Price:

10 µg/$281; 50 µg/$440; 200 µg/$877; 100 µg/$702; 1 mg/$1,983; 500 µg/$1,523; 5 mg/$3,067; 2 mg/$2,170

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Rat DKK1 Protein (Recombinant His-GST) (aa36-260) - LS-G12737

Source:

E. coli

Tag:

His-GST

Molecular Weight:

56.3 kDa

Price:

10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148

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Human DKK1 Protein (Recombinant His) (aa33-266) - LS-G12738

Source:

E. coli

Tag:

His

Molecular Weight:

27.2 kDa

Price:

10 µg/$268; 50 µg/$362; 100 µg/$577; 200 µg/$722; 1 mg/$1,755; 500 µg/$1,325; 5 mg/$2,708; 2 mg/$1,934

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Human DKK1 Protein (Recombinant His) - LS-G2291

Source:

E. coli

Tag:

His

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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Human DKK1 Protein (Recombinant His) - LS-G495

Source:

Baculovirus

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Price:

10 µg/$311; 50 µg/$498

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DKK1 Protein (Recombinant) (Ser30-His272) - LS-G27007

Source:

CHO Cells

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.2 EU/µg protein (determined by LAL method).

Molecular Weight:

19-20 kDa (SDS-PAGE)

Price:

50 µg/$478; 10 µg/$300; 1 mg/$2,976

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Human DKK1 Protein (Recombinant 8His, N-terminus) (Thr32-His266) - LS-G39129

Source:

Human Cells

Tag:

8His, N-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

27kD

Price:

10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,353

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Human DKK1 Protein (Recombinant 6His, N-terminus) (Thr32-His266) - LS-G26380

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

26 kDa

Price:

10 µg/$265; 50 µg/$315; 100 µg/$365

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Human DKK1 Protein (Recombinant GST, N-terminus) (aa81-180) - LS-G61885

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human DKK1 Protein (Recombinant DDK,C-terminus) - LS-G142459

Source:

Sf9 Cells

Tag:

DDK,C-terminus

Molecular Weight:

25.7 kDa

Price:

20 µg/$677

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DKK1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G101060

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

28.67 kDa

Price:

100 µg/$494

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Human DKK1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G83424

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

28.67 kDa

Price:

20 µg/$150

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Human DKK1 Protein (Recombinant GST) (Full Length) - LS-G32686

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

55 kDa

Price:

2 µg/$439

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