DKK1

dickkopf WNT signaling pathway inhibitor 1

Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.

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Products

Antibodies (93)

Type

Primary (93)

Target

DKK1 (93)

Reactivity

Human (81)

Mouse (23)

Rat (19)

Bat (7)

Bovine (7)

Chicken (3)

Chimpanzee (6)

Dog (7)

Gibbon (6)

Goat (4)

Guinea pig (6)

Horse (8)

Monkey (9)

Orangutan (3)

Pig (16)

Rabbit (6)

Rhesus monkey (3)

Xenopus (3)

Zebrafish (6)

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Application

IHC (7)

IHC-P (6)

WB (79)

ELISA (29)

IF (1)

Neut (1)

Peptide-ELISA (2)

Host

rabbit (74)

mouse (17)

goat (1)

sheep (1)

Product Group

IHCPlus (3)

Isotype

IgG (35)

IgG1 (2)

IgG2b (3)

IgG2b,k (10)

Clonality

monoclonal mc (18)

polyclonal pc (75)

Clone

08 (1)

2A5 (1)

2B12 (1)

2H2 (2)

R015 (1)

Format

APC (3)

APC Conjugated (6)

Atto 390 Conjugated (1)

Atto 488 Conjugated (1)

Atto 594 Conjugated (1)

Azide-free (1)

Biotin Conjugated (10)

Cy3 Conjugated (3)

Cy7 Conjugated (3)

FITC Conjugated (9)

HRP Conjugated (8)

PE Conjugated (5)

PerCP Conjugated (1)

Preservative Free (3)

RPE Conjugated (1)

Unconjugated (44)

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Epitope

C-Terminus (9)

aa33-266 (8)

aa36-260 (8)

aa58-84 (7)

Gln75 (1)

Internal (1)

Internal Region (1)

N-Terminus (1)

Ser140 (1)

aa150-200 (1)

aa250-262 (1)

aa68-83 (1)

aa71-266 (1)

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Publications

No (90)

Yes (3)

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IHC-plus™ DKK1 Antibody (aa250-262) LS-B194

(5.0) Rating

(2) Publication(s)

Antibody:

DKK1 Goat anti-Human Polyclonal (aa250-262) Antibody

Reactivity:

Mouse, Goat, Dog, Bovine, Pig, Horse, Human, Monkey

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µg/$485

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IHC-plus™ DKK1 Antibody (Internal Region) LS-A2867

Fast Shipping

(4.0) Rating

Antibody:

DKK1 Rabbit anti-Human Polyclonal (Internal Region) Antibody

Reactivity:

Human

Applications:

IHC-P

Format:

Unconjugated

Price:

50 µg/$440

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DKK1 Antibody LS-C331011

Antibody:

DKK1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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DKK1 Antibody (aa150-200) LS-C47394

(4.0) Rating

(1) Publication(s)

Antibody:

DKK1 Rabbit anti-Human Polyclonal (aa150-200) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$386

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DKK1 Antibody (C-Terminus) LS-C201644

(4.0) Rating

(1) Publication(s)

Antibody:

DKK1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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DKK1 Antibody (C-Terminus, FITC) LS-C459589

Antibody:

DKK1 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody

Reactivity:

Chicken, Zebrafish, Pig, Horse, Bat, Rat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Orangutan, Chimpanzee

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• FITC

• Unconjugated
• FITC

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IHC-plus™ DKK1 Antibody (N-Terminus) LS-A2866

Fast Shipping

(4.0) Rating

Antibody:

DKK1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$460

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IHC-plus™ DKK1 Antibody (Internal) LS-A2868

Fast Shipping

(4.0) Rating

Antibody:

DKK1 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Pig, Horse, Bat, Human, Monkey

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$460

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DKK1 Antibody LS-C343550

Antibody:

DKK1 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

20 µg/$242; 100 µg/$304; 200 µg/$334; 500 µg/$452

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DKK1 Antibody (clone 2A5) LS-C105117

Antibody:

DKK1 Mouse anti-Human Monoclonal (2A5) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$423

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DKK1 Antibody (clone 2H2) LS-C108793

Antibody:

DKK1 Mouse anti-Human Monoclonal (2H2) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µl/$403

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DKK1 Antibody (Biotin) LS-C684974

Antibody:

DKK1 Mouse anti-Human Monoclonal (Biotin) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$314; 200 µl/$359; 500 µl/$506; 1 ml/$580; 2 ml/$797; 5 ml/$1,295

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DKK1 Antibody LS-C64746

Antibody:

DKK1 Sheep anti-Rat Polyclonal Antibody

Reactivity:

Rat

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$930

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DKK1 Antibody (C-Terminus) LS-C6401

Antibody:

DKK1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

50 µg/$553; 100 µg/$820

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DKK1 Antibody (C-Terminus) LS-C81144

Antibody:

DKK1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$397

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DKK1 Antibody (C-Terminus, HRP) LS-C450638

Antibody:

DKK1 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody

Reactivity:

Xenopus, Zebrafish, Pig, Horse, Rabbit, Goat, Dog, Guinea pig, Bovine, Bat, Rat, Gibbon, Human, Monkey, Chimpanzee

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$442

• Unconjugated
• HRP

• Unconjugated
• HRP

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DKK1 Antibody (aa71-266) LS-C332169

Antibody:

DKK1 Rabbit anti-Human Polyclonal (aa71-266) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

Select

DKK1 Antibody LS-C665096

Antibody:

DKK1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

100 µg/$331

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DKK1 Antibody (clone R015, Preservative Free) LS-C820652

Antibody:

DKK1 Rabbit anti-Human Monoclonal (Preservative Free) (R015) Antibody

Reactivity:

Human

Applications:

Neut

Format:

Unconjugated, Preservative Free

Price:

200 µg/$398; 500 µg/$511

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DKK1 Antibody LS-C485867

Antibody:

DKK1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

100 µl/$412

Select

DKK1 Antibody LS-C356441

Antibody:

DKK1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

400 µl/$393

Select

DKK1 Antibody (clone 2B12) LS-C105116

Antibody:

DKK1 Mouse anti-Human Monoclonal (2B12) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$423

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DKK1 Antibody LS-C812441

Antibody:

DKK1 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$332; 100 µg/$404; 200 µg/$505

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DKK1 Antibody LS-C121732

Antibody:

DKK1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$884

Select

DKK1 Antibody (aa58-84) LS-C320850

Antibody:

DKK1 Rabbit anti-Human Polyclonal (aa58-84) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

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