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DCK / Deoxycytidine kinase
deoxycytidine kinase
Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity.
| Gene Name: | deoxycytidine kinase |
| Synonyms: | DCK, Deoxynucleoside kinase, Deoxycytidine kinase |
| Target Sequences: | NM_000788 NP_000779.1 P27707 |
Publications (6)
1
Clinicopathological significance of deoxycytidine kinase expression in esophageal squamous cell carcinoma. Shimada Y, Okumura T, Sekine S, Moriyama M, Hojo S, Matsui K, Sawada S, Nagata T, Fukuoka J, Tsukada K. Molecular and clinical oncology. 2013 1:716-720. (IHC; Human)
[Full Text Article]
[PubMed:24649234]
[PMC:PMC3915311]
Related Antibodies: LS-B1825.
2
The augmented expression of the cytidine deaminase gene by 5-azacytidine predicts therapeutic efficacy in myelodysplastic syndromes. Murakami Y, Kimura Y, Kawahara A, Mitsuyasu S, Miyake H, Tohyama K, Endo Y, Yoshida N, Imamura Y, Watari K, Ono M, Okamura T, Kuwano M. Oncotarget. 2019 March;10:2270-2281. [Full Text Article]
[PubMed:31040918]
[PMC:PMC6481348]
Related Antibodies: LS-B1825.
3
Human equilibrative nucleoside transporter-1 (hENT1) and ribonucleotide reductase regulatory subunit M1 (RRM1) expression; do they have survival impact to pancreatic cancer?. Dae Wook Hwang, Eun Shin, Jai Young Cho, Ho-Seong Han, Yoo-Seok Yoon. Annals of hepato-biliary-pancreatic surgery. 2020 May;24:127-136. [Full Text Article]
[PubMed:32457256]
[PMC:PMC7271117]
Related Antibodies: LS-C172855.
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DCK / Deoxycytidine kinase Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
DCK / Deoxycytidine kinase Mouse anti-Human Monoclonal (OTI16G6) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
100 µl/$434
DCK / Deoxycytidine kinase Mouse anti-Human Monoclonal (Carrier-free) (OTI16G6) Antibody
Human
Flo, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
DCK / Deoxycytidine kinase Rabbit anti-Human Polyclonal (aa171-200) Antibody
Mouse, Human
IF, IHC, IHC-P, IP, WB
Unconjugated
400 µl/$393
DCK / Deoxycytidine kinase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$460
DCK / Deoxycytidine kinase Mouse anti-Human Monoclonal (OTI3F5) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
DCK / Deoxycytidine kinase Mouse anti-Human Monoclonal (Carrier-free) (OTI3F5) Antibody
Human
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
DCK / Deoxycytidine kinase Rabbit anti-Human Polyclonal (aa210-260) Antibody
Mouse, Human
IHC, IHC-P, IP, WB
Unconjugated
50 µl/$460
DCK / Deoxycytidine kinase Rabbit anti-Human Polyclonal (aa108-157) Antibody
Human
WB
Unconjugated
100 µl/$424
DCK / Deoxycytidine kinase Rabbit anti-Human Polyclonal (aa171-200) Antibody
Mouse, Human
ELISA, IF, IHC, IP, WB
Unconjugated
200 µl/$734
DCK / Deoxycytidine kinase Rabbit anti-Human Polyclonal (aa171-200) (Biotin) Antibody
Mouse, Human
ELISA, ICC, IF, IHC, IP, WB
Biotin Conjugated
200 µl/$952
DCK / Deoxycytidine kinase Rabbit anti-Human Polyclonal (aa171-200) (FITC) Antibody
Mouse, Human
ELISA, ICC, IF, IHC, IP, WB
FITC Conjugated
200 µl/$952
DCK / Deoxycytidine kinase Rabbit anti-Human Polyclonal (aa171-200) (APC) Antibody
Mouse, Human
ELISA, ICC, IF, IHC, IP, WB
APC Conjugated
200 µl/$952
DCK / Deoxycytidine kinase Rabbit anti-Human Polyclonal (aa171-200) (PE) Antibody
Mouse, Human
ELISA, ICC, IF, IHC, IP, WB
PE Conjugated
200 µl/$952
DCK / Deoxycytidine kinase Rabbit anti-Human Polyclonal (aa171-200) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, ICC, IF, IHC, IP, WB
HRP Conjugated, Azide-free
200 µl/$952
DCK / Deoxycytidine kinase Rabbit anti-Human Polyclonal (aa180-229) (FITC) Antibody
Rabbit, Mouse, Dog, Bovine, Pig, Bat, Gibbon, Human, Monkey
WB
FITC Conjugated
100 µl/$469
DCK / Deoxycytidine kinase Mouse anti-Human Monoclonal (OTI15E12) Antibody
Human
Flo, IF, WB
Unconjugated
100 µl/$434
DCK / Deoxycytidine kinase Mouse anti-Human Monoclonal (Carrier-free) (OTI15E12) Antibody
Human
Flo, IF, WB
Unconjugated, Carrier-free
100 µg/$511
DCK / Deoxycytidine kinase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
DCK / Deoxycytidine kinase Mouse anti-Human Monoclonal (OTI16E12) Antibody
Human
Flo, WB
Unconjugated
100 µl/$434
DCK / Deoxycytidine kinase Mouse anti-Human Monoclonal (Carrier-free) (OTI16E12) Antibody
Human
Flo, WB
Unconjugated, Carrier-free
100 µg/$511
DCK / Deoxycytidine kinase Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
10 µg/$318; 100 µg/$470
DCK / Deoxycytidine kinase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
DCK / Deoxycytidine kinase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
DCK / Deoxycytidine kinase Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
50 µg/$294; 100 µg/$360
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