CSPG4 / NG2

chondroitin sulfate proteoglycan 4

Proteoglycan playing a role in cell proliferation and migration which stimulates endothelial cells motility during microvascular morphogenesis. May also inhibit neurite outgrowth and growth cone collapse during axon regeneration. Cell surface receptor for collagen alpha 2(VI) which may confer cells ability to migrate on that substrate. Binds through its extracellular N-terminus growth factors, extracellular matrix proteases modulating their activity. May regulate MPP16-dependent degradation and invasion of type I collagen participating in melanoma cells invasion properties. May modulate the plasminogen system by enhancing plasminogen activation and inhibiting angiostatin. Functions also as a signal transducing protein by binding through its cytoplasmic C-terminus scaffolding and signaling proteins. May promote retraction fiber formation and cell polarization through Rho GTPase activation. May stimulate alpha-4, beta-1 integrin-mediated adhesion and spreading by recruiting and activating a signaling cascade through CDC42, ACK1 and BCAR1. May activate FAK and ERK1/ERK2 signaling cascades.

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Products

Proteins (5)

Type

Over-Expression Lysate (1)

Recombinant (4)

Target

CSPG4 / NG2 (5)

Publications

No (5)

Tag

6His, N-terminus (1)

His (2)

His-GST (1)

Myc-DDK (Flag) (1)

Species

Human (2)

Rat (2)

Source

E. coli (4)

HEK 293 Cells (1)

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Human CSPG4 / NG2 Protein (Recombinant 6His, N-terminus) (aa559-776) - LS-G13384

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

25.1 kDa

Price:

10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060

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Rat CSPG4 / NG2 Protein (Recombinant His) (aa1135-1444) - LS-G13387

Source:

E. coli

Tag:

His

Molecular Weight:

34.8 kDa

Price:

10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284

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Human CSPG4 / NG2 Protein (Recombinant His) (aa1705-1942) - LS-G13382

Source:

E. coli

Tag:

His

Molecular Weight:

26.5 kDa

Price:

10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060

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Rat CSPG4 / NG2 Protein (Recombinant His-GST) (aa1919-2258) - LS-G13388

Source:

E. coli

Tag:

His-GST

Molecular Weight:

63.6 kDa

Price:

10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284

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CSPG4 / NG2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G118323

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

250.4 kDa

Price:

100 µg/$710

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