COMT

catechol-O-methyltransferase

Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters.

☰ Filters

Products

Antibodies (70)

ELISA Kits (13)

Proteins (11)

Type

Custom (5)

Development Kit (1)

Over-Expression Lysate (2)

Primary (70)

Recombinant (9)

Sandwich (7)

Target

COMT (94)

Reactivity

Human (59)

Mouse (30)

Rat (18)

Bat (1)

Bovine (5)

Chimpanzee (3)

Dog (3)

Gibbon (3)

Horse (4)

Monkey (7)

Pig (6)

Rabbit (3)

more less

Application

IHC (17)

IHC-P (11)

WB (64)

Flo (1)

ELISA (9)

ICC (5)

IF (4)

IP (3)

Peptide-ELISA (6)

Host

rabbit (64)

mouse (3)

goat (3)

Product Group

DevKit DuoPlus (1)

IHCPlus (8)

Isotype

IgG (28)

IgG1 (1)

IgG2b,k (1)

Clonality

monoclonal mc (2)

polyclonal pc (68)

Clone

1G4-1A1 (1)

Format

96-Well Microplate (1)

96-Well Strip Plate (11)

Antibody Pair and Standard (1)

APC (3)

APC Conjugated (4)

Biotin Conjugated (6)

Cy3 Conjugated (3)

Cy7 Conjugated (3)

FITC Conjugated (5)

HRP Conjugated (5)

PE Conjugated (4)

Preservative Free (1)

Unconjugated (40)

more less

Epitope

aa52-271 (9)

aa63-264 (8)

aa63-265 (8)

Internal (5)

aa143-192 (4)

30-110 aa, Internal (1)

C-Terminus (1)

Internal Region (1)

N-Terminus (1)

aa111-156 (1)

aa170-183 (1)

aa221-271 (1)

aa37-65 (1)

aa52-101 (1)

aa52-65 (1)

aa61-110 (1)

aa94-108 (1)

more less

Publications

No (92)

Yes (2)

Sample Type

Cell Culture Supernatants (3)

Cell Lysates (4)

Plasma (6)

Serum (6)

Tissue Homogenates (5)

Tag

6His, N-terminus (1)

GST (1)

His (3)

His, N-Terminal (1)

Myc-DDK (Flag) (4)

Species

Human (8)

Mouse (1)

Rat (1)

Source

293T Cells (1)

E. coli (6)

HEK 293 Cells (3)

Wheat Germ Extract (1)

Purification

Purified (3)

Low Endotoxin Level

Low endotoxin level (1)

Select

IHC-plus™ COMT Antibody (Internal) LS-A8834

Fast Shipping

(4.0) Rating

Antibody:

COMT Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$460

Select

IHC-plus™ COMT Antibody (aa52-65) LS-B4880

(4.0) Rating

Antibody:

COMT Goat anti-Human Polyclonal (aa52-65) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µg/$485

Select

IHC-plus™ COMT Antibody (aa170-183) LS-B4343

(5.0) Rating

(1) Publication(s)

Antibody:

COMT Goat anti-Human Polyclonal (aa170-183) Antibody

Reactivity:

Bovine, Pig, Horse, Human, Monkey

Applications:

ELISA, IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µg/$485

Select

Human COMT (Sandwich ELISA) ELISA Kit - LS-F13132

(4.0) Rating

(1) Publication(s)

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

Select

Human COMT (Sandwich ELISA) ELISA Kit - LS-F6763

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$730

Select

IHC-plus™ COMT Antibody (Internal) LS-A8833

Fast Shipping

(4.0) Rating

Antibody:

COMT Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Mouse, Bovine, Rat, Pig, Bat, Human, Monkey

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$460

Select

IHC-plus™ COMT Antibody (C-Terminus) LS-A8836

Fast Shipping

(4.0) Rating

Antibody:

COMT Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$460

Select

Rat COMT Protein (Recombinant His) (aa63-264) - LS-G16026

Source:

E. coli

Tag:

His

Molecular Weight:

24.0 kDa

Price:

10 µg/$283; 50 µg/$452; 200 µg/$902; 1 mg/$2,016; 5 mg/$3,151; 2 mg/$2,204

Select

COMT Antibody (Internal) LS-C352043

Antibody:

COMT Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

ICC, IF, WB

Format:

Unconjugated

Price:

100 µl/$299

Select

COMT Antibody LS-C664700

Antibody:

COMT Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IF, IHC, IP, WB

Format:

Unconjugated

Price:

100 µg/$331

Select

COMT Antibody LS-C490215

Antibody:

COMT Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ICC, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$575

Select

COMT Antibody (aa52-271) LS-C407752

Antibody:

COMT Rabbit anti-Human Polyclonal (aa52-271) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ICC, IHC, IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

Select

COMT Antibody LS-C334555

Antibody:

COMT Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

Select

Human COMT Protein (Recombinant) - LS-G3376

Source:

E. coli

Tag:

None

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Price:

100 µg/$511; 500 µg/$1,348; 20 µg/$311

Select

Human COMT Protein (Recombinant His) (aa52-271) - LS-G16024

Source:

E. coli

Tag:

His

Molecular Weight:

25.8 kDa

Price:

10 µg/$275; 50 µg/$402; 200 µg/$802; 1 mg/$1,876; 5 mg/$2,838; 2 mg/$2,060

Select

IHC-plus™ COMT Antibody (N-Terminus) LS-A8831

Fast Shipping

(4.0) Rating

Antibody:

COMT Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$460

Select

COMT Antibody LS-C830464

Antibody:

COMT Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

IHC-plus™ COMT Antibody (Internal) LS-A9769

Fast Shipping

(4.0) Rating

Antibody:

COMT Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$460

Select

IHC-plus™ COMT Antibody (Internal) LS-A9797

Fast Shipping

(4.0) Rating

Antibody:

COMT Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$460

Select

COMT Antibody (aa94-108) LS-C313303

Antibody:

COMT Rabbit anti-Human Polyclonal (aa94-108) Antibody

Reactivity:

Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

Select

COMT Antibody (30-110 aa, Internal) LS-C382850

Antibody:

COMT Rabbit anti-Human Polyclonal (30-110 aa, Internal) Antibody

Reactivity:

Human

Applications:

ELISA, ICC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

COMT Antibody LS-C830481

Antibody:

COMT Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

COMT Antibody (clone 1G4-1A1) LS-C196950

Antibody:

COMT Mouse anti-Human Monoclonal (1G4-1A1) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$423

Select

COMT Antibody (aa221-271) LS-C290293

Antibody:

COMT Rabbit anti-Human Polyclonal (aa221-271) Antibody

Reactivity:

Human

Applications:

IHC, IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

Select

COMT Antibody LS-C804918

Antibody:

COMT Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Viewing 1-25 of 94 product results

(0) Selected Add Selected To Cart Compare Selected Email Selected Clear Selected Top Of Search

If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.