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COL1A1 / Collagen I Alpha 1
collagen, type I, alpha 1
COL1A1 / Collagen I Alpha 1 is the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.
| Gene Name: | collagen, type I, alpha 1 |
| Family/Subfamily: | Collagen , not assigned-Collagen |
| Synonyms: | COL1A1, Alpha-1 type I collagen, Collagen alpha 1 chain type I, Collagen alpha-1(I) chain, Collagen, type I, alpha 1, Collagen I, Pro-alpha-1 collagen type 1, OI4 |
| Target Sequences: | NM_000088 NP_000079.2 P02452 |
Publications (9)
1
The Role of Periostin in Capsule Formation on Silicone Implants. Bae HS, Son HY, Lee JP, Chang H, Park JU. BioMed research international. 2018 April;2018:3167037. (Mouse, Human)
[Full Text Article]
[PubMed:29854742]
[PMC:PMC5944282]
Related Antibodies: LS-C343921.
2
Morphological Heterogeneity in Pancreatic Cancer Reflects Structural and Functional Divergence. Petra Sántha, Daniela Lenggenhager, Anette Finstadsveen, Linda Dorg, Kristin Tøndel, Manoj Amrutkar, Ivar P Gladhaug, Caroline Verbeke. Cancers. 2021 February;13: [Full Text Article]
[PubMed:33672734]
[PMC:PMC7924365]
Related Antibodies: LS-B5932.
3
Mechanical process prior to cryopreservation of lipoaspirates maintains extracellular matrix integrity and cell viability: evaluation of the retention and regenerative potential of cryopreserved fat-derived product after fat grafting. Jingwei Feng, Wansheng Hu, Mimi Lalrimawii Fanai, Shengqian Zhu, Jing Wang, Junrong Cai, Feng Lu. Stem cell research & therapy. 2019 September;10:283. [Full Text Article]
[PubMed:31547884]
[PMC:PMC6755707]
Related Antibodies: LS-B5932.
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(78)
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COL1A1 / Collagen I Alpha 1
(78)
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(56)
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(8)
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(25)
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Publications
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(76)
Yes
(2)
Cancer
COL1A1 / Collagen I Alpha 1 Mouse anti-Human Monoclonal (3G3) Antibody
Mouse, Human
ELISA, IHC-P, WB
Unconjugated
50 µg/$460
COL1A1 / Collagen I Alpha 1 Rabbit anti-Mouse Polyclonal (aa1192-1207) Antibody
Mouse, Rat, Human
ICC, IHC, IHC-Fr, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
COL1A1 / Collagen I Alpha 1 Rabbit anti-Chicken Polyclonal Antibody
Chicken
ELISA, IF, IHC-P, RIA, WB
Unconjugated
0.1 ml/$532
COL1A1 / Collagen I Alpha 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
100 µl/$469
COL1A1 / Collagen I Alpha 1 Goat Polyclonal (FITC) Antibody
Chicken, Mouse, Rat, Human
ELISA, EM, FLISA, Flo, ICC, IHC-Fr, IHC-P, IP, WB
FITC Conjugated
0.2 mg/$554
COL1A1 / Collagen I Alpha 1 Mouse anti-Human Monoclonal (3C3) Antibody
Mouse, Rat, Human
IHC-P
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
COL1A1 / Collagen I Alpha 1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Rabbit, Mouse, Dog, Bovine, Rat, Human
WB
Unconjugated
100 µl/$299
COL1A1 / Collagen I Alpha 1 Rabbit anti-Mouse Polyclonal (aa1225-1453) (APC, Cy7) Antibody
Mouse
WB
APC, Cy7 Conjugated
100 µl/$483; 200 µl/$599; 500 µl/$1,089; 1 ml/$1,297; 2 ml/$1,815; 5 ml/$3,403
COL1A1 / Collagen I Alpha 1 Rabbit anti-Mouse Polyclonal (aa1225-1453) (PE) Antibody
Mouse
WB
PE Conjugated
100 µl/$392; 200 µl/$470; 500 µl/$798; 1 ml/$951; 2 ml/$1,211; 5 ml/$2,269
COL1A1 / Collagen I Alpha 1 Mouse anti-Human Monoclonal (FITC) Antibody
Human
FITC Conjugated
100 µl/$363; 200 µl/$429; 500 µl/$672; 1 ml/$833; 2 ml/$1,076; 5 ml/$1,912
COL1A1 / Collagen I Alpha 1 Mouse anti-Human Monoclonal (APC) Antibody
Human
APC Conjugated
100 µl/$429; 200 µl/$523; 500 µl/$924; 1 ml/$1,092; 2 ml/$1,457; 5 ml/$2,731
COL1A1 / Collagen I Alpha 1 Mouse anti-Human Monoclonal (PE) Antibody
Human
PE Conjugated
100 µl/$429; 200 µl/$523; 500 µl/$924; 1 ml/$1,092; 2 ml/$1,457; 5 ml/$2,731
COL1A1 / Collagen I Alpha 1 Rabbit anti-Bovine Polyclonal Antibody
Sheep, Bovine, Pig, Cow, Human
ELISA, IF, IHC-P, RIA, WB
Unconjugated
0.1 ml/$498; 0.5 ml/$950
COL1A1 / Collagen I Alpha 1 Rabbit anti-Mouse Polyclonal (aa1185-1207) Antibody
Mouse, Rat
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
COL1A1 / Collagen I Alpha 1 Rabbit anti-Human Polyclonal (aa1077-1106) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
COL1A1 / Collagen I Alpha 1 Rabbit anti-Human Polyclonal (aa1077-1106) (APC) Antibody
Mouse, Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
COL1A1 / Collagen I Alpha 1 Rabbit anti-Human Polyclonal (aa1077-1106) (PE) Antibody
Mouse, Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
COL1A1 / Collagen I Alpha 1 Rabbit anti-Human Polyclonal (aa1194-1218) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µg/$575
COL1A1 / Collagen I Alpha 1 Rabbit anti-Rat Polyclonal (HRP) Antibody
Rat
ELISA, IHC, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
COL1A1 / Collagen I Alpha 1 Rabbit anti-Rat Polyclonal (Biotin) Antibody
Rat
ELISA, IHC, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
COL1A1 / Collagen I Alpha 1 Rabbit anti-Human Polyclonal (DY488) Antibody
Mouse
IHC, IHC-P
DY488 Conjugated
0.1 ml/$416
COL1A1 / Collagen I Alpha 1 Rabbit anti-Human Polyclonal (Biotin) Antibody
Mouse, Human
IHC, IHC-P
Biotin Conjugated
0.1 ml/$416
COL1A1 / Collagen I Alpha 1 Rabbit anti-Human Polyclonal (aa1188-1237) Antibody
Mouse, Human
WB
Unconjugated
100 µl/$424
COL1A1 / Collagen I Alpha 1 Rabbit anti-Rat Polyclonal (FITC) Antibody
Rat
ELISA, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
COL1A1 / Collagen I Alpha 1 Rabbit anti-Human Polyclonal (aa1216-1265) (HRP) Antibody
Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey
WB
HRP Conjugated
100 µl/$469
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