CLDN1 / Claudin 1

claudin 1

Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia. While some claudin family members play essential roles in the formation of impermeable barriers, others mediate the permeability to ions and small molecules. Often, several claudin family members are coexpressed and interact with each other, and this determines the overall permeability. CLDN1 is required to prevent the paracellular diffusion of small molecules through tight junctions in the epidermis and is required for the normal barrier function of the skin. Required for normal water homeostasis and to prevent excessive water loss through the skin, probably via an indirect effect on the expression levels of other proteins, since CLDN1 itself seems to be dispensable for water barrier formation in keratinocyte tight junctions (PubMed:23407391). CLDN1 acts as a coreceptor for HCV entry into hepatic cells.

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Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

CLDN1 / Claudin 1 (5)

Publications

No (5)

Tag

GST (1)

His-GST (1)

Myc-DDK (Flag) (3)

Species

Human (4)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human CLDN1 / Claudin 1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G89009

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

22.6 kDa

Price:

20 µg/$150

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Human CLDN1 / Claudin 1 Protein (Recombinant GST) (Full Length) - LS-G31466

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

48.95 kDa

Price:

2 µg/$439

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Human CLDN1 / Claudin 1 Protein (Recombinant His-GST) (aa50-197) - LS-G14908

Source:

E. coli

Tag:

His-GST

Molecular Weight:

48.1 kDa

Price:

10 µg/$281; 50 µg/$440; 100 µg/$702; 200 µg/$877; 1 mg/$1,983; 500 µg/$1,523; 5 mg/$3,067; 2 mg/$2,170

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Human CLDN1 / Claudin 1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G71155

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

22.6 kDa

Price:

20 µg/$1,107

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CLDN1 / Claudin 1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G101716

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

22.6 kDa

Price:

100 µg/$494

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