CDKN1A / WAF1 / p21

cyclin-dependent kinase inhibitor 1A (p21, Cip1)

CDKN1A / WAF1 / p21 is a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-CDK2 or -CDK4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli. This protein can interact with proliferating cell nuclear antigen (PCNA), a DNA polymerase accessory factor, and plays a regulatory role in S phase DNA replication and DNA damage repair. This protein was reported to be specifically cleaved by CASP3-like caspases, which thus leads to a dramatic activation of CDK2, and may be instrumental in the execution of apoptosis following caspase activation. Multiple alternatively spliced variants have been found for this gene.

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Products

ELISA Kits (11)

Type

Cell-Based (1)

Cell-Based Phosphorylation (1)

Custom (1)

Sandwich (8)

Target

CDKN1A / WAF1 / p21 (11)

Reactivity

Human (5)

Mouse (4)

Rat (5)

Bovine (1)

Format

12 x 8-Well Microstrips (2)

96-Well Microplate (2)

96-Well Strip Plate (7)

Publications

No (11)

Sample Type

Adherent Cell Cultures (2)

Cell Culture Supernatants (2)

Cell Lysates (3)

Plasma (6)

Serum (6)

Tissue Homogenates (5)

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Mouse/Human/Rat CDKN1A / WAF1 / p21 (Cell-Based ELISA) ELISA Kit - LS-F2202

Type:

Cell-Based

Format:

96-Well Microplate

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$534

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Human CDKN1A / WAF1 / p21 (Sandwich ELISA) ELISA Kit - LS-F38083

Type:

Sandwich

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

78.13 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates

Price:

1 Plate/$651

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Human CDKN1A / WAF1 / p21 (Sandwich ELISA) ELISA Kit - LS-F20417

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

31.2 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$669

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Rat CDKN1A / WAF1 / p21 (Sandwich ELISA) ELISA Kit - LS-F6933

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$783

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Mouse CDKN1A / WAF1 / p21 (Sandwich ELISA) ELISA Kit - LS-F38248

Type:

Sandwich

Format:

12 x 8-Well Microstrips

Reactivity:

Mouse

Range:

0.16 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

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Mouse/Human/Rat Phospho-CDKN1A / WAF1 / p21 (Thr145) (Cell-Based Phosphorylation ELISA) ELISA Kit - LS-F1584

Type:

Cell-Based Phosphorylation

Format:

96-Well Microplate

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

2 Plates/$668

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Rat CDKN1A / WAF1 / p21 (Sandwich ELISA) ELISA Kit - LS-F32873

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

78.125 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Bovine CDKN1A / WAF1 / p21 (Sandwich ELISA) ELISA Kit - LS-F36239

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Bovine

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Rat CDKN1A / WAF1 / p21 (Sandwich ELISA) ELISA Kit - LS-F38623

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

78.125 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

Select

Mouse CDKN1A / WAF1 / p21 (Custom ELISA) ELISA Kit - LS-F20416

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

Select

Human CDKN1A / WAF1 / p21 (Sandwich ELISA) ELISA Kit - LS-F55027

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$730

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