CDK12 / CRKRS

cyclin-dependent kinase 12

Cyclin-dependent kinase that phosphorylates the C-terminal domain (CTD) of the large subunit of RNA polymerase II (POLR2A), thereby acting as a key regulator of transcription elongation. Regulates the expression of genes involved in DNA repair and is required for the maintenance of genomic stability. Preferentially phosphorylates 'Ser-5' in CTD repeats that are already phosphorylated at 'Ser-7', but can also phosphorylate 'Ser-2'. Required for RNA splicing, possibly by phosphorylating SRSF1/SF2. Involved in regulation of MAP kinase activity, possibly leading to affect the response to estrogen inhibitors.

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Products

Antibodies (17)

ELISA Kits (5)

Proteins (5)

Type

Custom (1)

Over-Expression Lysate (4)

Primary (17)

Recombinant (1)

Sandwich (4)

Target

CDK12 / CRKRS (27)

Reactivity

Human (19)

Mouse (9)

Rat (4)

Dog (1)

Monkey (1)

Application

IHC (1)

IHC-P (1)

WB (13)

ELISA (9)

IP (1)

Peptide-ELISA (1)

Host

rabbit (16)

mouse (1)

Product Group

Alzheimer's Disease (27)

PathPlus Neuro (1)

Isotype

IgG (13)

IgG2a,k (1)

Clonality

monoclonal mc (1)

polyclonal pc (16)

Clone

3C1 (1)

Format

96-Well Strip Plate (5)

APC Conjugated (1)

Azide-free (1)

Biotin Conjugated (2)

FITC Conjugated (2)

HRP Conjugated (2)

PE Conjugated (1)

Unconjugated (9)

Epitope

aa1-30 (7)

Internal (1)

aa1-50 (1)

Publications

No (26)

Yes (1)

Sample Type

Cell Lysates (1)

Plasma (3)

Serum (3)

Tissue Homogenates (1)

Tag

GST (1)

Myc-DDK (Flag) (4)

Species

Human (3)

Source

293T Cells (2)

HEK 293 Cells (2)

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PathPlus™ CDK12 / CRKRS Antibody (Internal) LS-A7350

Neuroscience

Fast Shipping

(5.0) Rating

Antibody:

CDK12 / CRKRS Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Dog, Human, Monkey

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$460

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CDK12 / CRKRS Antibody (clone 3C1) LS-C105145

Antibody:

CDK12 / CRKRS Mouse anti-Human Monoclonal (3C1) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$423

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CDK12 / CRKRS Antibody (aa1-30) LS-C99890

Antibody:

CDK12 / CRKRS Rabbit anti-Human Polyclonal (aa1-30) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

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CDK12 / CRKRS Antibody (aa1-50) LS-C288466

(4.0) Rating

(1) Publication(s)

Antibody:

CDK12 / CRKRS Rabbit anti-Human Polyclonal (aa1-50) Antibody

Reactivity:

Human

Applications:

IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

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Human CDK12 / CRKRS (Sandwich ELISA) ELISA Kit - LS-F35287

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

78.125 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$579

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CDK12 / CRKRS Antibody LS-C673839

Antibody:

CDK12 / CRKRS Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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CDK12 / CRKRS Antibody (HRP) LS-C675149

Antibody:

CDK12 / CRKRS Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

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CDK12 / CRKRS Antibody (Biotin) LS-C673838

Antibody:

CDK12 / CRKRS Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

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CDK12 / CRKRS Antibody (FITC) LS-C675150

Antibody:

CDK12 / CRKRS Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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CDK12 / CRKRS Antibody LS-C749874

Antibody:

CDK12 / CRKRS Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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CDK12 / CRKRS Antibody (aa1-30) LS-C330372

Antibody:

CDK12 / CRKRS Rabbit anti-Human Polyclonal (aa1-30) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

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CDK12 / CRKRS Antibody (aa1-30, Biotin) LS-C243905

Antibody:

CDK12 / CRKRS Rabbit anti-Human Polyclonal (aa1-30) (Biotin) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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CDK12 / CRKRS Antibody (aa1-30, FITC) LS-C243906

Antibody:

CDK12 / CRKRS Rabbit anti-Human Polyclonal (aa1-30) (FITC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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CDK12 / CRKRS Antibody (aa1-30, APC) LS-C243904

Antibody:

CDK12 / CRKRS Rabbit anti-Human Polyclonal (aa1-30) (APC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

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CDK12 / CRKRS Antibody (aa1-30, PE) LS-C243910

Antibody:

CDK12 / CRKRS Rabbit anti-Human Polyclonal (aa1-30) (PE) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

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CDK12 / CRKRS Antibody (aa1-30, Azide-free, HRP) LS-C247483

Antibody:

CDK12 / CRKRS Rabbit anti-Human Polyclonal (aa1-30) (Azide-free) (HRP) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• PE
• HRP, Azide-free

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • PE
  • HRP, Azide-free

Select

Human CDK12 / CRKRS (Sandwich ELISA) ELISA Kit - LS-F13113

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Rat CDK12 / CRKRS (Sandwich ELISA) ELISA Kit - LS-F20086

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Mouse CDK12 / CRKRS (Sandwich ELISA) ELISA Kit - LS-F20087

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

Select

CDK12 / CRKRS Antibody LS-C779709

Antibody:

CDK12 / CRKRS Rabbit anti-Human Polyclonal Antibody

Reactivity:

Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

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CDK12 / CRKRS Antibody LS-C802292

Antibody:

CDK12 / CRKRS Rabbit anti-Human Polyclonal Antibody

Reactivity:

Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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Bovine CDK12 / CRKRS (Custom ELISA) ELISA Kit - LS-F20088

Type:

Custom

Format:

96-Well Strip Plate

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

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CDK12 / CRKRS Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G112617

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

164 kDa

Price:

100 µg/$710

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Human CDK12 / CRKRS Protein (Recombinant GST) - LS-G132176

Tag:

GST

Molecular Weight:

36.63kDa

Price:

10 µg/$479; 25 µg/$670

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Human CDK12 / CRKRS Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G90444

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

163 kDa

Price:

20 µg/$215

Viewing 1-25 of 27 product results

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