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CDH2 / N Cadherin
cadherin 2, type 1, N-cadherin (neuronal)
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density.
| Gene Name: | cadherin 2, type 1, N-cadherin (neuronal) |
| Family/Subfamily: | Cadherin , not assigned-Cadherin |
| Synonyms: | CDH2, CDw325, CDHN, Cadherin-2, CD325, CD325 antigen, N Cadherin, N-cadherin, NCAD, Neural cadherin, N-cadherin 1, Neural-cadherin |
| Target Sequences: | NM_001792 NP_001783.2 P19022 |
Publications (21)
1
Identification of plakoglobin domains required for association with N-cadherin and alpha-catenin. Sacco PA, McGranahan TM, Wheelock MJ, Johnson KR. The Journal of biological chemistry. 1995 270:20201-6.
[PubMed:7650039]
2
Interaction of alpha-actinin with the cadherin/catenin cell-cell adhesion complex via alpha-catenin. Knudsen KA, Soler AP, Johnson KR, Wheelock MJ. The Journal of cell biology. 1995 130:67-77.
[PubMed:7790378]
[PMC:PMC2120515]
3
The differential expression of N-cadherin and E-cadherin distinguishes pleural mesotheliomas from lung adenocarcinomas. Peralta Soler A, Knudsen KA, Jaurand MC, Johnson KR, Wheelock MJ, Klein-Szanto AJ, Salazar H. Human pathology. 1995 26:1363-9.
[PubMed:8522310]
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CDH2 / N Cadherin Mouse anti-Human Monoclonal (5D5) Antibody
Human
ELISA, Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$485
CDH2 / N Cadherin Mouse anti-Human Monoclonal (OTI2G7) Antibody
Mouse, Dog, Human, Monkey
Flo, IHC, IHC-P, WB
Unconjugated
100 µl/$434
CDH2 / N Cadherin Mouse anti-Human Monoclonal (Carrier-free) (OTI2G7) Antibody
Mouse, Dog, Rat, Human, Monkey
Flo, IHC, WB
Unconjugated, Carrier-free
100 µg/$501
CDH2 / N Cadherin Mouse anti-Human Monoclonal (Cytoplasmic Domain) (13A9) Antibody
Mouse, Human
ICC, IF, IP, WB
Unconjugated
0.1 ml/$386
CDH2 / N Cadherin Mouse anti-Chicken Monoclonal (Intracellular) Antibody
Chicken, Rat, Pig, Mouse, Human
IF, IHC, IHC-P, IP, WB
Unconjugated
100 µg/$807
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$798
CDH2 / N Cadherin Mouse anti-Human Monoclonal (Biotin) (8C11) Antibody
Human
Flo
Biotin Conjugated
100 µg/$382
CDH2 / N Cadherin Mouse anti-Human Monoclonal Antibody
Mouse, Rat, Human
ELISA, Flo, IF, IHC, WB
Unconjugated
50 µg/$332; 100 µg/$404; 200 µg/$505
CDH2 / N Cadherin Rabbit anti-Human Polyclonal (aa808-827) Antibody
Chicken, Bovine, Mouse, Human
IHC, IHC-Fr, IHC-P, WB
Unconjugated
400 µg/$1,201
CDH2 / N Cadherin Mouse anti-Chicken Monoclonal (GC-4) Antibody
Chicken, Rabbit, Mouse, Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$485
CDH2 / N Cadherin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
CDH2 / N Cadherin Rabbit anti-Human Monoclonal (aa1-724) Antibody
Human
ELISA, Flo, ICC, IF, WB
Unconjugated
20 µl/$271; 100 µl/$412
CDH2 / N Cadherin Rabbit anti-Human Polyclonal (aa701-714) Antibody
Rat, Human
IHC, WB
Unconjugated
100 µg/$380
CDH2 / N Cadherin Mouse anti-Human Monoclonal (Azide-free, BSA-free) (CDH2/1573) Antibody
Human
Flo, IF, IHC-P, WB
Unconjugated, Azide-free, BSA-free
100 µg/$574
Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$587
E. coli
His, N-Terminal
70 kDa
10 µg/$265; 200 µg/$484; 50 µg/$315
CDH2 / N Cadherin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
CDH2 / N Cadherin Rabbit anti-Human Monoclonal (aa1-724) Antibody
Human
ELISA, ICC, IF
Unconjugated
100 µl/$412
CDH2 / N Cadherin Rabbit anti-Human Monoclonal (aa1-724) Antibody
Human
ELISA, ICC, IF
Unconjugated
100 µl/$412
CDH2 / N Cadherin Rabbit anti-Human Monoclonal (Preservative Free) (001) Antibody
Human
ELISA, Flo
Unconjugated, Preservative Free
100 µl/$412
CDH2 / N Cadherin Mouse anti-Human Monoclonal (UMAB23) Antibody
Human
Flo, IF, IHC, WB
Unconjugated
100 µl/$493
CDH2 / N Cadherin Mouse anti-Human Monoclonal (Carrier-free) (UMAB23) Antibody
Human
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$539
CDH2 / N Cadherin Mouse anti-Human Monoclonal (Extracellular Domain) (OTI5F8) Antibody
Human
WB
Unconjugated
100 µl/$434
CDH2 / N Cadherin Mouse anti-Human Monoclonal (OTI3B10) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
100 µl/$434
CDH2 / N Cadherin Rabbit anti-Human Polyclonal (690-770 aa, C-terminal) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
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