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CD81

CD81 molecule

CD81 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This protein appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies. Two transcript variants encoding different isoforms have been found for this gene.

Gene Name: CD81 molecule
Family/Subfamily: Tetraspan , not assigned-Tetraspan
Synonyms: CD81, CD81 antigen, CD81 molecule, CVID6, S5.7, TAPA1, TAPA-1, Tetraspanin-28, TSPAN28, Tspan-28
Target Sequences: NM_004356 NP_004347.1 P60033

Publications (7)

1
Potentials and capabilities of the Extracellular Vesicle (EV) Array. Jørgensen MM, Bæk R, Varming K. Journal of Extracellular Vesicles. 2015 4:26048. (IHC; Human) [PubMed:25862471] [PMC:PMC4393420] Related Antibodies: LS-B7347.
2
Characterization of a Cell-Culturing System for the Study of Contact-Independent Extracellular Vesicle Communication. Revenfeld ALS, Søndergaard EKL, Stensballe A, Bæk R, Jørgensen MM, Varming K. Journal of circulating biomarkers. 2016 February;5:3. (Human) [Full Text Article] [PubMed:28936251] [PMC:PMC5548315] Related Antibodies: LS-B7347.
3
Induction of a Regulatory Phenotype in CD3+ CD4+ HLA-DR+ T Cells after Allogeneic Mixed Lymphocyte Culture; Indications of Both Contact-Dependent and -Independent Activation. Revenfeld ALS, Bæk R, Jørgensen MM, Varming K, Stensballe A. International journal of molecular sciences. 2017 July;18:pii: E1603. (Human) [Full Text Article] [PubMed:28737722] [PMC:PMC5536089] Related Antibodies: LS-B7347.
4
An miRNA fingerprint using neural-enriched extracellular vesicles from blood plasma: towards a biomarker for amyotrophic lateral sclerosis/motor neuron disease. Sandra Anne Banack, Rachael Anne Dunlop, Paul Alan Cox. Open biology. 2020 Jun;10:200116. [Full Text Article] [PubMed:32574550] [PMC:PMC7333885]
5
Enrichment of Neurodegenerative Microglia Signature in Brain-Derived Extracellular Vesicles Isolated from Alzheimer's Disease Mouse Models. Satoshi Muraoka, Mark P Jedrychowski, Naotoshi Iwahara, Mohammad Abdullah, Kristen D Onos, Kelly J Keezer, Jianqiao Hu, Seiko Ikezu, Gareth R Howell, Steven P Gygi, Tsuneya Ikezu. Journal of proteome research. 2021 Mar;20:1733-1743. [Full Text Article] [PubMed:33534581] [PMC:PMC7944570] Related Antibodies: LS-C350457.
6
Exploring the molecular content of CHO exosomes during bioprocessing. Christoph Keysberg , Oliver Hertel , Louise Schelletter , Tobias Busche, Chiara Sochart, Jörn Kalinowski, Raimund Hoffrogge , Kerstin Otte, Thomas Noll. Applied microbiology and biotechnology. 2021 May;;105:3673-3689. [Full Text Article] [PubMed:33937930] [PMC:PMC8102462] Related Antibodies: LS-C108453.
7
Extracellular Vesicle (EV) Array: microarray capturing of exosomes and other extracellular vesicles for multiplexed phenotyping. Jorgensen M1, Baek R, Pedersen S, Sondergaard EK, Kristensen SR, Varming K. Journal of Extracellular Vesicles. 2013 Jun 18;2: [Full Text Article] [PubMed:24009888] [PMC:PMC3760630] Related Antibodies: LS-B7347, LS-C35761.
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☰ Filters
Antibodies (109)
Proteins (11)
ELISA Kits (2)
Over-Expression Lysate (2)
Primary (109)
Recombinant (8)
Sandwich (2)
CD81 (122)
Human (74)
Mouse (40)
Rat (10)
Cat (3)
Chimpanzee (5)
Feline (6)
Gibbon (3)
Goat (2)
Rabbit (10)
Rodent (3)
Sheep (2)
IHC (28)
IHC-Fr (8)
IHC-P (27)
WB (52)
Flo (67)
Block (1)
ELISA (28)
Func (10)
ICC (14)
IF (10)
IP (29)
Peptide-ELISA (1)
SDS-PAGE (1)
rabbit (42)
mouse (47)
hamster (13)
hamster-armenian (6)
rat (1)
Product Group
IHCPlus (5)
PathPlus Cancer (2)
IgG (29)
IgG,k (1)
IgG1 (40)
IgG1,k (7)
IgG2a (1)
IgG2b (2)
IgG3 (1)
IgG3,k (5)
monoclonal mc (67)
polyclonal pc (38)
recombinant monoclonal rmc (4)
03 (2)
1.3.3.22 (10)
1668CT146.84.1 (1)
1668CT178.9.24.87 (1)
1668CT270.93.9 (1)
1D6 (8)
2B7 (1)
2E11E5 (1)
2F7 (6)
B399 (1)
C81/2885R (2)
Eat 2 (1)
Eat2 (7)
G1/G1-4 (1)
M38 (9)
96-Well Strip Plate (2)
APC (1)
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Azide-free (5)
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BSA-free (1)
Carrier-free (1)
Concentrated (2)
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Cy7 Conjugated (1)
DY488 Conjugated (1)
DY550 Conjugated (1)
FITC Conjugated (15)
HRP Conjugated (6)
Low Endotoxin (3)
PE Conjugated (10)
PerCP Conjugated (1)
RPE Conjugated (4)
Unconjugated (53)
aa113-201 (8)
aa116-201 (4)
aa170-219 (4)
90-210 aa, Internal (1)
Internal (1)
No (117)
Yes (5)
Cell Lysates (1)
Plasma (1)
Serum (1)
Tissue Homogenates (2)
Fc, N-terminus (1)
GST, N-terminus (1)
His (1)
His, N-Terminal (1)
His-SUMO (1)
Myc-DDK (Flag) (3)
Human (9)
Rat (1)
293T Cells (1)
E. coli (2)
HEK 293 Cells (4)
Human (1)
Wheat Germ Extract (1)
Yeast (1)
Purified (2)
Low endotoxin level (4)
CD81 Antibody - Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Cancer
CD81 Mouse anti-Human Monoclonal (1.3.3.22) Antibody
Human
Flo, IHC-P, WB
Unconjugated
50 µg/$515
CD81 Antibody - Immunohistochemistry of CD81 in human brain tissue with CD81 antibody at 2 µg/ml.
Select
CD81 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
0.1 mg/$460
Select
CD81 Mouse anti-Human Monoclonal (Biotin) (1.3.3.22) Antibody
Human
Flo, ICC, WB
Biotin Conjugated
100 µg/$725
CD81 Antibody - Anti-CD81 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.
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CD81 Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
CD81 Antibody - Immunohistochemistry Dilution at 1:100 and staining in paraffin-embedded human testis tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal Goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated Secondary antibody and visualized using an HRP conjugated SP system.
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CD81 Rabbit anti-Human Monoclonal Antibody
Mouse, Rat, Human
ELISA, Flo, IHC, IHC-P, WB
Unconjugated
50 µl/$316; 100 µl/$386
Select
CD81 Mouse anti-Human Monoclonal (M38) Antibody
Rabbit, Feline, Human
Flo, Func, ICC, IHC, IHC-P, IP, WB
Unconjugated
0.1 mg/$316
Select
CD81 Mouse anti-Human Monoclonal (Biotin) (M38) Antibody
Rabbit, Feline, Human
Flo, Func, ICC, IHC-P, IP, WB
Biotin Conjugated
0.1 mg/$337
CD81 Antibody - Flow cytometry of CD81 antibody This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CD81 Mouse anti-Human Monoclonal (Biotin) (1.3.3.22) Antibody
Human
Flo, ICC, WB
Biotin Conjugated
100 µg/$511
CD81 Antibody - All lanes: Anti-CD81 Antibody at 1:4000 dilution Lane 1: U-87 MG whole cell lysate Lane 2: human testis lysate Lane 3: rat cerebellum lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size: 26 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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CD81 Mouse anti-Human Monoclonal (1668CT178.9.24.87) Antibody
Rat, Human
ELISA, WB
Unconjugated
200 µl/$393
CD81 Antibody - Detection limit for recombinant GST tagged CD81 is approximately 0.1 ng/ml as a capture antibody.
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CD81 Mouse anti-Human Monoclonal (2B7) Antibody
Human
ELISA
Unconjugated
100 µg/$423
Select
CD81 Hamster-Armenian anti-Mouse Monoclonal (2F7) Antibody
Mouse
Flo, IHC, IHC-Fr, IP
Unconjugated
0.5 mg/$398
CD81 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
CD81 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$798
Select
CD81 Rat anti-Mouse Monoclonal Antibody
Mouse
Flo
Unconjugated
100 µg/$896
CD81 Protein - Recombinant Target Of The Antiproliferative Antibody 1 By SDS-PAGE
Select
E. coli
His, N-Terminal
13.4 kDa
10 µg/$290; 50 µg/$500; 100 µg/$797; 200 µg/$997; 1 mg/$2,139; 500 µg/$1,662; 5 mg/$3,487; 2 mg/$2,329
CD81 Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE), at a dilution of 1:100.
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CD81 Rabbit anti-Human Polyclonal (Internal) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
CD81 Protein
Select
HEK 293 Cells
None
SDS-PAGE
Less than 1.0 EU/µg protein (determined by LAL method).
The recombinant human CD81 comprises 91 amino acids and has a predicted molecular mass of 9.9 kDa. The apparent molecular mass of the monomer is approximately 10 kDa in SDS-PAGE under reducing conditions.
100 µg/$441
CD81 Antibody - Immunohistochemistry of paraffin-embedded mouse lung tissue.
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CD81 Rabbit anti-Human Polyclonal Antibody
Mouse
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
Select
CD81 Mouse anti-Human Monoclonal (PE) Antibody
Human
Flo
PE Conjugated
120 Tests/$725
Select
CD81 Mouse anti-Human Monoclonal (1D6) Antibody
Human
Flo, IF, IHC, IHC-P, IP, WB
Unconjugated
25 µg/$281; 0.2 mg/$471
Select
CD81 Mouse anti-Human Monoclonal (FITC) (1D6) Antibody
Human
Flo, IHC, IHC-P
FITC Conjugated
25 µg/$281; 0.1 mg/$432
CD81 Antibody - Western blot of CD81 antibody.
Select
CD81 Rabbit anti-Human Polyclonal (aa113-201) (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$331; 200 µl/$383; 500 µl/$556; 1 ml/$665; 2 ml/$901; 5 ml/$1,511
CD81 Antibody - Western blot of CD81 antibody.
Select
CD81 Rabbit anti-Human Polyclonal (aa113-201) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$313; 200 µl/$357; 500 µl/$503; 1 ml/$576; 2 ml/$788; 5 ml/$1,279
CD81 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
2 µg/$439
Select
CD81 Hamster anti-Mouse Monoclonal (Biotin) Antibody
Mouse, Rat, Rodent
ELISA, Flo, IHC, IP, WB
Biotin Conjugated
100 µl/$878
Viewing 1-25 of 122 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).