CD63

CD63 molecule

Functions as cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2. Plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGFR2. Plays a role in intracellular vesicular transport processes, and is required for normal trafficking of the PMEL luminal domain that is essential for the development and maturation of melanocytes. Plays a role in the adhesion of leukocytes onto endothelial cells via its role in the regulation of SELP trafficking. May play a role in mast cell degranulation in response to Ms4a2/FceRI stimulation, but not in mast cell degranulation in response to other stimuli.

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Products

Proteins (14)

Type

Over-Expression Lysate (2)

Recombinant (12)

Target

CD63 (14)

Application

SDS-PAGE (2)

Publications

No (14)

Tag

6His, N-terminus (3)

6His-SUMOstar, N-terminus (1)

Fc, N-terminus (1)

GST, N-terminus (1)

His (1)

His,C-terminus (3)

His-GST (1)

Myc-DDK (Flag) (3)

Species

Human (11)

Monkey-Cynomolgus (1)

Mouse (1)

Rat (1)

Source

293T Cells (1)

E. coli (5)

HEK 293 Cells (6)

Yeast (2)

Purification

Purified (5)

Low Endotoxin Level

Low endotoxin level (5)

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Human CD63 Protein (Recombinant 6His, N-terminus) (Ala103-Val203) - LS-G26412

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

14 kDa

Price:

10 µg/$265; 50 µg/$315; 100 µg/$365

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Human CD63 Protein (Recombinant His-GST) (aa103-203) - LS-G13687

Source:

E. coli

Tag:

His-GST

Molecular Weight:

43.9 kDa

Price:

10 µg/$291; 50 µg/$502; 100 µg/$802; 200 µg/$1,002; 1 mg/$2,144; 500 µg/$1,668; 5 mg/$3,501; 2 mg/$2,334

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Human CD63 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G118413

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

25.5 kDa

Price:

100 µg/$494

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Human CD63 Protein (Recombinant His,C-terminus) (Ala103-Val203) - LS-G48716

Source:

HEK 293 Cells

Tag:

His,C-terminus

Application:

SDS-PAGE

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

The recombinant human CD63 consists of 112 amino acids after removal of the signal peptide and has a predicted molecular mass of 13 kDa. The apparent molecular mass of rh CD63 is approximately 20-25 kDa in SDS-PAGE under reducing conditions.

Price:

100 µg/$441; 1 mg/$2,003

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Monkey-Cynomolgus CD63 Protein (Recombinant His,C-terminus) (Ala103-Val203) - LS-G49752

Source:

HEK 293 Cells

Tag:

His,C-terminus

Application:

SDS-PAGE

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

The recombinant cynomolgus CD63 comprises 112 amino acids and has a calculated molecular mass of 13 kDa. The apparent molecular mass of it is approximately 22 and 19 kDa in SDS-PAGE under reducing conditions.

Price:

100 µg/$480; 1 mg/$2,333

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Mouse CD63 Protein (Recombinant GST, N-terminus) (aa103-203) - LS-G56146

Source:

E. coli

Tag:

GST, N-terminus

Price:

1 mg/$1,679; 100 µg/$500; 20 µg/$364

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Human CD63 Protein (Recombinant 6His, N-terminus) - LS-G136577

Source:

Yeast

Tag:

6His, N-terminus

Molecular Weight:

13.5 kDa

Price:

100 µg/$570; 20 µg/$395; 1 mg/$1,973

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Human CD63 Protein (Recombinant 6His-SUMOstar, N-terminus) - LS-G136576

Source:

Yeast

Tag:

6His-SUMOstar, N-terminus

Molecular Weight:

27.5 kDa

Price:

100 µg/$570; 20 µg/$395; 1 mg/$1,973

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Human CD63 Protein (Recombinant 6His, N-terminus) - LS-G136979

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

15.5 kDa

Price:

1 mg/$1,679; 100 µg/$500; 20 µg/$364

Select

Human CD63 Protein (Recombinant His,C-terminus) (Ala103-Val203) - LS-G138033

Source:

HEK 293 Cells

Tag:

His,C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

13 kDa

Price:

100 µg/$721

Select

Rat CD63 Protein (Recombinant Fc, N-terminus) (Ala103-Val203) - LS-G138342

Source:

HEK 293 Cells

Tag:

Fc, N-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

38.1 kDa

Price:

100 µg/$843

Select

Human CD63 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G70728

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

25.5 kDa

Price:

20 µg/$1,107

Select

Human CD63 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G87848

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

25.5 kDa

Price:

20 µg/$150

Select

Human CD63 Protein (Recombinant His) (aa103-203) - LS-G141155

Source:

E. coli

Sequence Length:

100 AA

Tag:

His

Endotoxin Level:

Less than 0.1 EU/µg protein (determined by LAL method).

Molecular Weight:

11.11 kDa

Price:

10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531

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