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CD6 is a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. The gene product is important for continuation of T cell activation. This gene may be associated with susceptibility to multiple sclerosis (PMID: 19525953, 21849685). Multiple transcript variants encoding different isoforms have been found for this gene.
Gene Name: | CD6 molecule |
Synonyms: | CD6, CD6 molecule, T12, TP120, CD6 antigen |
Target Sequences: | NM_006725 NP_006716.3 P30203 |
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