Human CD6

Mouse

Human (tested or 100% immunogen sequence identity)

IgG1 Monoclonal

MEM-98

Unconjugated. Also available conjugated with FITC.

Protein G purified

Unmodified

Purified CD6 antigen.

Recognizes human CD6, also known as T12 or TP120. CD6 is a ~100-130 kD type 1 single pass trans-membrane protein member of the immunoglobulin superfamily. CD6 possesses 3 scavenger receptor cysteine rich domains in it's extracellular sequence. The membrane proximal SRCR3 contains the epitope responsible for interaction with CD166, also known as Activated Leukocyte Cell Adhesion Molecule or CD166. Multiple gene transcripts have been detected encoding CD6 in man resulting in the production of a number of CD6 isoforms. Recognizes an external epitope located in the membrane-distal SRCR domain 1 and is expected to recognize all CD6 isoforms so far identified,. CD6 has been implicated as a therapeutic target for a number of autoimmune conditions including Sjogren's syndrome, rheumatoid arthritis and psoriasis.

• IHC
• IHC - Paraffin (10 µg/ml)
• Western blot
• Immunoprecipitation
• Flow Cytometry (1:1)

Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells or 100 ul whole blood.

PBS, 0.09% Sodium Azide

Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P30203 NCBI: NM_006725 NP_006716.3