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6737 Mowry Ave
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CD40L
CD40 ligand
TNFSF5 is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in inability of immunoglobulin class switch and is associated with hyper IgM syndrome.
| Gene Name: | CD40 ligand |
| Family/Subfamily: | TNF , not assigned-TNF |
| Synonyms: | CD40LG, CD154, CD154 antigen, CD40-L, CD40 ligand, CD40L, gp39, HIGM1, IGM, IMD3, T-BAM, TNFSF5, CD40 antigen ligand, CD54, HCD40L, T-B cell-activating molecule, T-cell antigen Gp39, TNF-related activation protein |
| Target Sequences: | NM_000074 NP_000065.1 P29965 |
Publications (1)
1
Design and selection of anti-PD-L1 single-domain antibody and tumor necrosis factor superfamily ligands for an optimal vectorization in an oncolytic virus. Christelle Remy, Elodie Pintado, Marshall Dunlop, Shirley Schön, Patricia Kleinpeter, Homa Rozanes, Laetitia Fend, Renée Brandely, Michel Geist, Delphine Suhner, Eline Winter, Nathalie Silvestre, Claire Huguet, Peter Fitzgerald, Eric Quéméneur, Jean-Baptiste Marchand. Frontiers in bioengineering and biotechnology. 2023 December;11:1247802. [Full Text Article]
[PubMed:38053848]
[PMC:PMC10694795]
Related Antibodies: LS-C293374.
☰ Filters
Products
Proteins
(47)
Type
Over-Expression Lysate
(2)
Recombinant
(45)
Target
CD40L
(47)
Application
Bind
(3)
ELISA
(3)
Func
(3)
SDS-PAGE
(3)
Format
Animal-free
(1)
Publications
No
(47)
Tag
6His, N-terminus
(5)
6His-AVI, N-terminus
(1)
DDK (Flag)-Human ACRP30headless aa 18-111
(3)
GST
(2)
GST, N-terminus
(1)
His
(2)
His, N-Terminal
(2)
His,C-terminus
(2)
His,N-terminus
(2)
His-GST
(5)
His-S
(2)
Human IgG1 Fc
(1)
Human IgG1 Fc, N-terminus
(2)
Mouse IgG1 Fc, N-terminus
(1)
Myc-DDK (Flag)
(2)
Species
Bovine
(1)
Human
(30)
Mouse
(6)
Pig
(3)
Rabbit
(2)
Rat
(2)
Rhesus monkey
(2)
Source
293T Cells
(1)
CHO Cells
(4)
E. coli
(26)
HEK 293 Cells
(4)
Human
(2)
Human Cells
(1)
Mammalian Cells
(4)
Wheat Germ Extract
(2)
Yeast
(2)
Purification
Purified
(10)
Low Endotoxin Level
Low endotoxin level
(23)
Biologically Active
Biologically active
(13)
Animal-free
Animal-free
(1)
E. coli
6His, N-terminus
20.3 kD
1 mg/$1,679; 100 µg/$598; 20 µg/$405
E. coli
His, N-Terminal
14.4 kDa
10 µg/$307; 50 µg/$602; 100 µg/$962; 200 µg/$1,156; 1 mg/$2,369; 500 µg/$1,876; 5 mg/$4,201; 2 mg/$2,562
Yeast
6His, N-terminus
18.2 kD
100 µg/$679; 20 µg/$429; 1 mg/$1,973
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
16.3 kDa
10 µg/$268; 50 µg/$349
E. coli
None
Biologically active
Less than 0.01 ng/µg of protein (Less than 0.1 EU/µg).
10 µg/$281; 50 µg/$369
E. coli
None
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
~16 kDa
50 µg/$291; 250 µg/$494; 1 mg/$1,401
E. coli
His-GST
43.3 kDa
10 µg/$297; 50 µg/$542; 100 µg/$865; 200 µg/$1,065; 1 mg/$2,239; 500 µg/$1,755; 5 mg/$3,781; 2 mg/$2,430
E. coli
His
17.7 kDa
10 µg/$297; 50 µg/$542; 100 µg/$865; 200 µg/$1,065; 1 mg/$2,239; 500 µg/$1,755; 5 mg/$3,781; 2 mg/$2,430
CHO Cells
DDK (Flag)-Human ACRP30headless aa 18-111
Less than 0.02 EU/µg protein (determined by LAL method).
~35-40kDa
10 µg/$428
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
16.4 kDa
5 µg/$268; 25 µg/$349
E. coli
None
Biologically active
16.3 kDa
10 µg/$282; 100 µg/$503; 500 µg/$1,058
Human Cells
None
Less than 1.0 EU/µg protein (determined by LAL method).
16.2kD
10 µg/$281; 50 µg/$395; 500 µg/$1,585; 1 mg/$2,157
HEK 293 Cells
Human IgG1 Fc, N-terminus
Bind ELISA Func SDS-PAGE
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
The recombinant mouse CD40LG/Fc is a disulfide-linked homodimer. The reduced monomer comprises 406 amino acids and has a calculated molecular mass of 44.4 kDa. The apparent molecular mass of the monomer is approximately 50 kDa in SDS-PAGE under reducing conditions.
50 µg/$364; 500 µg/$1,379
E. coli
His,C-terminus
Bind ELISA Func SDS-PAGE
Biologically active
The recombinant human CD40L consists of 161 amino acids and has a calculated molecular mass of 17.7 kDa. It migrates as an 18 kDa band in SDS-PAGE under reducing conditions.
100 µg/$410; 1 mg/$2,261
HEK 293 Cells
Human IgG1 Fc, N-terminus
Bind ELISA Func SDS-PAGE
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
The recombinant human CD40L/Fc is a disulfide-linked homodimeric protein. The reduced monomer consists of 386 amino acids and has a predicted molecular mass of 42.8 kDa. The apparent molecular mass of rh CD40L/Fc monomer is approximately 45 kDa in SDS-PAGE under reducing conditions.
50 µg/$364; 500 µg/$1,285
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
HEK 293 Cells
Myc-DDK (Flag)
29.1 kDa
100 µg/$494
293T Cells
Myc-DDK (Flag)
29.1 kDa
20 µg/$150
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
16.2kD
10 µg/$248; 50 µg/$313; 500 µg/$743; 1 mg/$1,048
E. coli
None
Biologically active
Less than 1 EU/µg (determined by LAL method).
16.308 kDa
10 µg/$274; 1 mg/$1,475; 50 µg/$368
E. coli
None
Biologically active
Less than 1 EU/µg (determined by LAL method).
16.3 kDa
1 mg/$1,470; 50 µg/$364
Human
Mouse IgG1 Fc, N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
42.7 kDa
10 µg/$273; 50 µg/$398
Human
6His-AVI, N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
20.9 kDa
20 µg/$416; 100 µg/$910
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product results
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