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CD207 / Langerin

CD207 molecule, langerin

Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells. Major receptor on primary Langerhans cells for Candida species, Saccharomyces species, and Malassezia furfur. Protects against human immunodeficiency virus-1 (HIV-1) infection. Binds to high-mannose structures present on the envelope glycoprotein which is followed by subsequent targeting of the virus to the Birbeck granules leading to its rapid degradation.

Gene Name: CD207 molecule, langerin
Synonyms: CD207, CD207 antigen, langerin, CD207 antigen, CD207 molecule, langerin, CLEC4K, Langerin
Target Sequences: NM_015717 NP_056532.4 Q9UJ71

Publications (1)

1
Partial epithelial-mesenchymal transition in keloid scars: regulation of keloid keratinocyte gene expression by transforming growth factor-ß1. Hahn JM, McFarland KL, Combs KA, Supp DM. Burns & trauma. 2016 4:30. (IHC; Human) [Full Text Article] [PubMed:27574697] [PMC:PMC4994224] Related Antibodies: LS-C312086.

☰ Filters
Antibodies (30)
Proteins (8)
ELISA Kits (1)
Over-Expression Lysate (2)
Primary (30)
Recombinant (6)
Sandwich (1)
CD207 / Langerin (39)
Human (27)
Mouse (16)
Rat (4)
Chimpanzee (3)
Gibbon (3)
Guinea pig (3)
Horse (3)
Monkey (3)
Pig (3)
IHC (4)
IHC-Fr (4)
IHC-P (7)
WB (22)
Flo (2)
ELISA (8)
IP (2)
rabbit (25)
mouse (5)
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IHCPlus (2)
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PathPlus Cancer Pathology (3)
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IgG2b (1)
IgG2b,k (3)
monoclonal mc (4)
polyclonal pc (26)
12D6 (3)
1C5A1 (1)
96-Well Microplate (1)
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aa26-44 (1)
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Low endotoxin level (2)
CD207 / Langerin Antibody - Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Cancer Pathology
Cancer
CD207 / Langerin Mouse anti-Human Monoclonal (12D6) Antibody
Human
IHC, IHC-Fr, IHC-P
Unconjugated
0.05 ml/$460
CD207 / Langerin Antibody - Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE)
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CD207 / Langerin Mouse anti-Human Monoclonal (12D6) Antibody
Human
IHC-Fr, IHC-P
Unconjugated
0.1 ml/$358
CD207 / Langerin Antibody - IHC of Langerin on FFPE Skin tissue. This image was taken for the unmodified form of this product. Other forms have not been tested.
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CD207 / Langerin Mouse anti-Human Monoclonal (Ready-to-Use) (12D6) Antibody
Human
IHC-Fr, IHC-P
Unconjugated, Ready-to-Use
3 ml/$342
CD207 / Langerin Antibody - IHC of skin Langerin/CD207 in formalin-fixed, paraffin-embedded human (Langerhans cells) using antibody at 2.5 ug/ml. ?Hematoxylin-Eosin counterstain.
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CD207 / Langerin Rabbit anti-Mouse Polyclonal (aa26-44) Antibody
Mouse, Rat, Human
Flo, IHC, IHC-Fr, IHC-P, WB
Unconjugated
100 µg/$386
CD207 / Langerin Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
6His, N-terminus
1 mg/$1,679; 100 µg/$500; 20 µg/$364
CD207 / Langerin Antibody - Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE)
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CD207 / Langerin Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
CD207 / Langerin Antibody - Human Skin Langerhans Cells: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Cancer Pathology
Cancer
CD207 / Langerin Mouse anti-Human Monoclonal (1C5A1) Antibody
Human
ELISA, Flo, IHC-P, WB
Unconjugated
100 µl/$485
CD207 / Langerin Antibody - CD207 / LANGERIN antibody Western Blot of Fetal Kidney . Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CD207 / Langerin Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
CD207 / Langerin Antibody - Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE)
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CD207 / Langerin Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC-P, WB
Unconjugated
50 µl/$460
CD207 / Langerin Antibody - Human Skin Langerhans Cells: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Cancer Pathology
Cancer
CD207 / Langerin Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC
Unconjugated
120 µl/$460
Select
Human
6His, N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
31.5kD
50 µg/$395; 500 µg/$1,585; 1 mg/$2,157; 10 µg/$281
CD207 / Langerin ELISA Kit
Select
Sandwich
96-Well Microplate
Human
0.102 - 25 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$610
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CD207 / Langerin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$331
CD207 / Langerin Antibody - Western blot of CD207 antibody
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CD207 / Langerin Rabbit anti-Human Polyclonal (61-110 aa, Internal) Antibody
Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
CD207 / Langerin Antibody - Western blot analysis of lysate from K562 cells, using CD207 Antibody.
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CD207 / Langerin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
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CD207 / Langerin Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IP, WB
Unconjugated
100 µl/$749
Select
CD207 / Langerin Rabbit anti-Human Polyclonal Antibody
Human
IP, WB
Unconjugated
100 µl/$412
Select
CD207 / Langerin Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA
Unconjugated
50 µg/$294; 100 µg/$360
Select
CD207 / Langerin Rabbit anti-Mouse Polyclonal (HRP) Antibody
Mouse
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
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CD207 / Langerin Rabbit anti-Mouse Polyclonal (Biotin) Antibody
Mouse
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
CD207 / Langerin Rabbit anti-Mouse Polyclonal (FITC) Antibody
Mouse
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
Select
CD207 / Langerin Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
100 µg/$749
Select
CD207 / Langerin Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µl/$412
CD207 / Langerin Antibody - Western blot of extracts of HeLa cell lines, using ERBB2 antibody.
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CD207 / Langerin Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
50 µl/$356; 100 µl/$461
Select
CD207 / Langerin Mouse anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µg/$705
Viewing 1-25 of 39 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).