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CD20

membrane-spanning 4-domains, subfamily A, member 1

CD20 is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. This family member is localized to 11q12, among a cluster of family members. Alternative splicing of this gene results in two transcript variants which encode the same protein.

Gene Name: membrane-spanning 4-domains, subfamily A, member 1
Synonyms: MS4A1, B-lymphocyte antigen CD20, B1, Bp35, CD20, CD20 antigen, CD20 receptor, LEU-16, CVID5
Target Sequences: NM_021950 NP_690605.1 P11836

Publications (4)

1
BDNF and its receptors in human myasthenic thymus: implications for cell fate in thymic pathology. Berzi A, Ayata CK, Cavalcante P, Falcone C, Candiago E, Motta T, Bernasconi P, Hohlfeld R, Mantegazza R, Meinl E, Farina C. Journal of neuroimmunology. 2008 197:128-39. (ICC) [PubMed:18555538]
2
Humanized Mice Exhibit Exacerbated Abscess Formation and Osteolysis During the Establishment of Implant-Associated Staphylococcus aureus Osteomyelitis. Gowrishankar Muthukrishnan, Alexandra Wallimann, Javier Rangel-Moreno, Karen L de Mesy Bentley, Maria Hildebrand, Karen Mys, H Mark Kenney, Eric T Sumrall, John L Daiss, Stephan Zeiter, R Geoff Richards, Edward M Schwarz, T Fintan Moriarty. Frontiers in immunology. 2021 April;12:651515. [Full Text Article] [PubMed:33815412] [PMC:PMC8012494] Related Antibodies: LS-B2605.
3
PD-1 blockade and vaccination provide therapeutic benefit against SIV by inducing broad and functional CD8+ T cells in lymphoid tissue. Sheikh Abdul Rahman, Bhrugu Yagnik, Alexander P Bally, Kristen N Morrow, Shelly Wang, Thomas H Vanderford, Gordon J Freeman, Rafi Ahmed, Rama Rao Amara. Science immunology. 2021 September;6:eabh3034. [Full Text Article] [PubMed:34516743] [PMC:PMC8500359] Related Antibodies: LS-B11144.
4
Tumor-initiating properties of breast cancer and melanoma cells in vivo are not invariably reflected by spheroid formation in vitro, but can be increased by long-term culturing as adherent monolayers. Kuch V, Schreiber C, Thiele W, Umansky V, Sleeman JP. International journal of cancer. Journal international du cancer. 2013 Feb;132:E94-105. [Full Text Article] [PubMed:22907275] Related Antibodies: LS-C13105.
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Antibodies (214)
Primary (214)
CD20 (214)
Human (194)
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CD20 Antibody - Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
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CD20 Goat anti-Human Polyclonal (aa284-297) Antibody
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
CD20 Antibody - Anti-MS4A1 / CD20 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
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CD20 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P, IP, WB
Unconjugated
125 µl/$515
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CD20 Mouse anti-Human Monoclonal (B9E9) Antibody
Mouse, Rat, Human
ELISA, Flo, IHC, IHC-Fr, IP
Unconjugated
100 µg/$543; 500 µg/$1,079
CD20 Antibody - Mouse Thymus: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Cancer Pathology
Cancer
CD20 Rabbit anti-Mouse Polyclonal Antibody
Mouse, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
CD20 Antibody - Mouse Thymus: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CD20 Rabbit anti-Mouse Polyclonal (HRP) Antibody
Mouse
ELISA, IHC, IHC-P, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
CD20 Antibody - Mouse Thymus: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CD20 Rabbit anti-Mouse Polyclonal (FITC) Antibody
Mouse
ELISA, IHC, IHC-P, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
CD20 Antibody - IHC testing of CD20 antibody and FFPE human tonsil tissue
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CD20 Mouse anti-Human Monoclonal (L26 + IGEL/733) Antibody
Human, Monkey
Flo, IF, IHC, IHC-P
Unconjugated
0.1 ml/$371; 0.5 ml/$574
CD20 Antibody - Western Blot of Balb/c thymus (lane 1) and A20 (lane 2) cell lysates with anti-mouse CD20 monoclonal antibody (clone: AISB12).
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CD20 Rat anti-Mouse Monoclonal (AISB12) Antibody
Mouse
Flo, WB
Unconjugated
100 µg/$298
CD20 Antibody - Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Cancer Pathology
Cancer
CD20 Mouse anti-Human Recombinant Monoclonal (rIGEL/773) Antibody
Human
Flo, IF, IHC-P
Unconjugated
100 µg/$525
CD20 Antibody - Formalin-fixed, paraffin-embedded human Tonsil stained with CD20 Mouse Recombinant Monoclonal Antibody (rIGEL/773).
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CD20 Mouse anti-Human Recombinant Monoclonal (Azide-free, Carrier-free) (rIGEL/773) Antibody
Human
Flo, IF, IHC-P
Unconjugated, Azide-free, Carrier-free
100 µg/$574
CD20 Antibody - Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Cancer Pathology
Cancer
CD20 Rabbit anti-Human Recombinant Monoclonal (IGEL/1497R) Antibody
Human
Flo, IHC-P
Unconjugated
100 µg/$525
CD20 Antibody - Anti-MS4A1 / CD20 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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Cancer Pathology
Cancer
CD20 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P
Unconjugated
100 µl/$460
CD20 Antibody - Immunohistochemistry of CD20 antibody
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CD20 Mouse anti-Human Monoclonal (2F4) Antibody
Mouse, Rat, Human
IHC
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
CD20 Antibody - IHC of paraffin-embedded Human lymphoma tissue using anti-MS4A1 mouse monoclonal antibody.
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CD20 Mouse anti-Human Monoclonal (OTI4A4) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
CD20 Antibody - CD20 Antibody in Immunoprecipitation (IP)
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CD20 Mouse anti-Bovine Monoclonal (MEM-97) Antibody
Bovine, Pig, Human
Flo, IP
Unconjugated
100 µg/$423
CD20 Antibody - Western blot of recombinant CD20.
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CD20 Rabbit anti-Mouse Polyclonal (aa8-251) Antibody
Mouse
WB
Unconjugated
100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206
CD20 Antibody - Immunoperoxidase of monoclonal antibody to MS4A1 on formalin-fixed paraffin-embedded human tonsil. [antibody concentration 3 ug/ml]
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CD20 Mouse anti-Human Monoclonal (aa1-298) (4F11) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
100 µg/$423
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CD20 Mouse anti-Human Polyclonal Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
50 µg/$705
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CD20 Mouse anti-Human Monoclonal (FITC) Antibody
Human
Flo, IHC, IHC-Fr
FITC Conjugated
100 Tests/$577
CD20 Antibody - Anti-CD20 antibody IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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CD20 Mouse anti-Human Monoclonal (4B4) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
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CD20 Mouse anti-Human Monoclonal (CAT13.6E12) Antibody
Human
IHC, IHC-Fr
Unconjugated
100 µg/$523
CD20 Antibody - Immunoprecipitation of human CD20 from the whole cell lysate of RAJI human Burkitt lymphoma cell line.  Western blot was immunostained with anti-CD20 rabbit polyclonal antibody.  Lane 1: original lysate of RAJI cells  Lane 2: immunoprecipitate by Isotypic mouse IgG1 control (PPV-06)  Lane 3: original lysate of RAJI cells  Lane 4: immunoprecipitate by anti-CD20 (MEM-97)
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CD20 Mouse anti-Human Monoclonal (Azide-free) (MEM-97) Antibody
Bovine, Porcine, Human
Flo, IP
Unconjugated, Azide-free
0.1 mg/$302
CD20 Antibody - Immunoprecipitation of human CD20 from the whole cell lysate of RAJI human Burkitt lymphoma cell line.  Western blot was immunostained with anti-CD20 rabbit polyclonal antibody.  Lane 1: original lysate of RAJI cells  Lane 2: immunoprecipitate by Isotypic mouse IgG1 control (PPV-06)  Lane 3: original lysate of RAJI cells  Lane 4: immunoprecipitate by anti-CD20 (MEM-97)
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CD20 Mouse anti-Human Monoclonal (MEM-97) Antibody
Bovine, Porcine, Human
Flo, IP
Unconjugated
0.1 mg/$302
CD20 Antibody - Flow-cytometry on human lymphocytes.
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CD20 Human anti-Human Recombinant Monoclonal (CD20) (10F381 (rituximab)) Antibody
Human, Monkey-Cynomolgus, Monkey-Rhesus
Flo
Unconjugated
0.2 mg/$540
CD20 Antibody - Immunohistochemical staining of paraffin-embedded human spleen using anti-CD20 clone UMAB58 mouse monoclonal antibody at 1:200 dilution of 1mg/mL and detection with Polink2 Broad HRP DAB.requires heat-induced epitope retrieval withCitrate pH6.0 for 3minutes at110C in pressure chamber. The image shows the cells in the white pulp have strong cytoplasmic and membraneous staining.
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CD20 Mouse anti-Human Monoclonal (Carrier-free) (UMAB58) Antibody
Human
IF, IHC, PMA, WB
Unconjugated, Carrier-free
100 µg/$539
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).