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CCL26 / Eotaxin 3 is one of two Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 7. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for normal peripheral blood eosinophils and basophils. The product of this gene is one of three related chemokines that specifically activate chemokine receptor CCR3. This chemokine may contribute to the eosinophil accumulation in atopic diseases.
Gene Name: | chemokine (C-C motif) ligand 26 |
Family/Subfamily: | Intercrine , Intercrine beta |
Synonyms: | CCL26, CC chemokine IMAC, Ccl26, Ccl26l, C-C motif chemokine 26, Chemokine N1, Eotaxin-3, Eotaxin 3, Eoxtaxin-3, MIP-4-alpha, IMAC, SCYA26, Small inducible cytokine A26, Thymic stroma chemokine-1, MIP-4alpha, TSC-1, Small-inducible cytokine A26, Eotaxin3, MIP-4a |
Target Sequences: | NM_006072 NP_006063.1 Q9Y258 |
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