CASP1 / Caspase 1

caspase 1, apoptosis-related cysteine peptidase

CASP1 / Caspase 1 is a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing results in transcript variants encoding distinct isoforms.

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Antibodies (115)

ELISA Kits (29)

Proteins (16)

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Custom (3)

Development Kit (1)

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Primary (115)

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Sandwich (20)

Sandwich CLIA (3)

Target

CASP1 / Caspase 1 (160)

Reactivity

Human (113)

Mouse (49)

Rat (35)

Chicken (1)

Dog (1)

Guinea pig (1)

Horse (3)

Monkey (1)

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rabbit (108)

mouse (4)

goat (1)

rat (2)

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monoclonal mc (6)

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aa120-297 (17)

aa119-296 (16)

aa317-404 (8)

aa30-79 (4)

pSer376 (4)

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Internal (3)

Cleaved-Asp210 (2)

aa371-390 (2)

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aa101-150 (1)

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Adherent Cell Cultures (2)

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Species

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Mouse (1)

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Rat (2)

Source

293T Cells (4)

E. coli (6)

HEK 293 Cells (4)

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Purification

Purified (1)

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IHC-plus™ CASP1 / Caspase 1 Antibody (aa371-390, clone 14F468) LS-B112

(4.0) Rating

Antibody:

CASP1 / Caspase 1 Mouse anti-Human Monoclonal (aa371-390) (14F468) Antibody

Reactivity:

Mouse, Human

Applications:

ICC, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

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CASP1 / Caspase 1 Antibody (aa206-220, clone 1H11) LS-C21290

Antibody:

CASP1 / Caspase 1 Rat anti-Mouse Monoclonal (aa206-220) (1H11) Antibody

Reactivity:

Mouse

Applications:

ELISA, Flo, WB

Format:

Unconjugated

Price:

100 µg/$755

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CASP1 / Caspase 1 Antibody (aa249-262) LS-C312683

Antibody:

CASP1 / Caspase 1 Rabbit anti-Human Polyclonal (aa249-262) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

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CASP1 / Caspase 1 Antibody (130-210 aa, Internal) LS-C380449

Antibody:

CASP1 / Caspase 1 Rabbit anti-Human Polyclonal (130-210 aa, Internal) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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CASP1 / Caspase 1 Antibody (aa120-297) LS-C293197

Antibody:

CASP1 / Caspase 1 Rabbit anti-Pig Polyclonal (aa120-297) Antibody

Reactivity:

Pig, Human

Applications:

ICC, IP, WB

Format:

Unconjugated

Price:

100 µl/$323; 200 µl/$371; 500 µl/$531; 1 ml/$617; 2 ml/$850; 5 ml/$1,401

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CASP1 / Caspase 1 Antibody (aa120-297, Biotin) LS-C300783

Antibody:

CASP1 / Caspase 1 Rabbit anti-Pig Polyclonal (aa120-297) (Biotin) Antibody

Reactivity:

Pig, Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$334; 200 µl/$387; 500 µl/$563; 1 ml/$678; 2 ml/$915; 5 ml/$1,541

• Unconjugated
• Biotin

• Unconjugated
• Biotin

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CASP1 / Caspase 1 Antibody (aa120-297, Biotin) LS-C299556

Antibody:

CASP1 / Caspase 1 Rabbit anti-Human Polyclonal (aa120-297) (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$313; 200 µl/$357; 500 µl/$503; 1 ml/$576; 2 ml/$788; 5 ml/$1,279

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CASP1 / Caspase 1 Antibody (aa30-79, Biotin) LS-C465718

Antibody:

CASP1 / Caspase 1 Rabbit anti-Human Polyclonal (aa30-79) (Biotin) Antibody

Reactivity:

Horse, Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

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CASP1 / Caspase 1 Antibody (aa317-404, Biotin) LS-C299851

Antibody:

CASP1 / Caspase 1 Rabbit anti-Human Polyclonal (aa317-404) (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$313; 200 µl/$357; 500 µl/$503; 1 ml/$576; 2 ml/$788; 5 ml/$1,279

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CASP1 / Caspase 1 Antibody (clone 3D2) LS-C133008

Antibody:

CASP1 / Caspase 1 Mouse anti-Human Monoclonal (3D2) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$423

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Human CASP1 / Caspase 1 (Sandwich ELISA) ELISA Kit - LS-F11012

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

15.6 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Ascites, Cell Culture Supernatants, Cerebrospinal Fluid, Plasma, Saliva, Serum, Tissue Homogenates, Urine

Price:

1 Plate/$585

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Human CASP1 / Caspase 1 Protein (Recombinant GST, N-terminus) (aa1-100) - LS-G57985

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human CASP1 / Caspase 1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66088

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

29.6 kDa

Price:

20 µg/$1,107

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Human CASP1 / Caspase 1 Protein (Recombinant GST) (Full Length) - LS-G27743

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

61.4 kDa

Price:

2 µg/$439

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IHC-plus™ CASP1 / Caspase 1 Antibody LS-B3200

(4.0) Rating

Antibody:

CASP1 / Caspase 1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

0.05 mg/$460

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Mouse/Human/Rat CASP1 / Caspase 1 (Cell-Based ELISA) ELISA Kit - LS-F1851

Type:

Cell-Based

Format:

96-Well Microplate

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$534

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Dog CASP1 / Caspase 1 (Sandwich ELISA) ELISA Kit - LS-F18070

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Dog

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Mouse CASP1 / Caspase 1 Protein (Recombinant His, N-Terminal) (aa119-296) - LS-G14039

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

21.6 kDa

Price:

10 µg/$271; 50 µg/$382; 100 µg/$610; 200 µg/$762; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998

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CASP1 / Caspase 1 Antibody LS-B3199

Antibody:

CASP1 / Caspase 1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

0.05 mg/$460

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Rat CASP1 / Caspase 1 Protein (Recombinant His, N-Terminal) - LS-G132743

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

21kDa

Price:

10 µg/$370; 50 µg/$922; 200 µg/$1,577; 100 µg/$1,345; 1 mg/$2,945; 500 µg/$2,397; 5 mg/$6,441; 2 mg/$3,436

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CASP1 / Caspase 1 Antibody (aa225-242) LS-C21288

Antibody:

CASP1 / Caspase 1 Rabbit anti-Human Polyclonal (aa225-242) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ICC, IP, WB

Format:

Unconjugated

Price:

100 µg/$854

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CASP1 / Caspase 1 Antibody (170-250 aa, Internal) LS-C380453

Antibody:

CASP1 / Caspase 1 Rabbit anti-Human Polyclonal (170-250 aa, Internal) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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CASP1 / Caspase 1 Antibody (N-Terminus) LS-C47034

Antibody:

CASP1 / Caspase 1 Rabbit anti-Insect Polyclonal (N-Terminus) Antibody

Applications:

ELISA, WB

Format:

Unconjugated

Price:

0.1 mg/$379

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CASP1 / Caspase 1 Antibody (aa137-157) LS-C343884

Antibody:

CASP1 / Caspase 1 Rabbit anti-Mouse Polyclonal (aa137-157) Antibody

Reactivity:

Mouse, Rat

Applications:

WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

Select

CASP1 / Caspase 1 Antibody (aa119-296) LS-C293193

Antibody:

CASP1 / Caspase 1 Rabbit anti-Rat Polyclonal (aa119-296) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$312; 200 µl/$355; 500 µl/$500; 1 ml/$573; 2 ml/$780; 5 ml/$1,268

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