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BMP7

bone morphogenetic protein 7

The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development and possible bone inductive activity.

Gene Name: bone morphogenetic protein 7
Family/Subfamily: TGF beta , not assigned-TGF beta
Synonyms: BMP7, Bone morphogenetic protein 7, Eptotermin alfa, OP-1, OP1, Osteogenic protein 1, BMP-7
Target Sequences: NM_001719 NP_001710.1 P18075

Publications (1)

1
BMP-7 induces apoptosis in human germinal center B cells and is influenced by TGF-ß receptor type I ALK5. Bollum LK, Huse K, Oksvold MP, Bai B, Hilden VI, Forfang L, Yoon SO, Wälchli S, Smeland EB, Myklebust JH. PloS one. 2017 12:e0177188. (WB; Human) [Full Text Article] [PubMed:28489883] [PMC:PMC5425193] Related Antibodies: LS-C293046.

☰ Filters
Products
Proteins (15)
Over-Expression Lysate (2)
Recombinant (13)
BMP7 (15)
No (15)
GST (2)
His (4)
His, N-Terminal (1)
His-T7 (2)
Myc-DDK (Flag) (2)
Bovine (1)
Human (11)
Mouse (2)
293T Cells (1)
CHO Cells (2)
E. coli (10)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Purified (4)
Low endotoxin level (4)
Biologically active (2)
Select
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
~17 kDa
10 µg/$395; 1 mg/$6,619
BMP7 Protein
Select
E. coli
His
Less than 1.0 EU/µg protein (determined by LAL method).
100 µg/$317; 500 µg/$526; 20 µg/$245
BMP7 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
49.31 kDa
100 µg/$494
BMP7 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
49.31 kDa
20 µg/$150
Select
E. coli
None
Less than 0.2 EU/µg protein (determined by LAL method).
15.7 kDa
10 µg/$364; 1 mg/$6,620
Select
CHO Cells
None
Biologically active
Less than 0.1 ng/µg of protein.
The 117 amino acid recombinant protein has a predicted molecular mass of approximately 13 kD. Recombinant human BMP-7 is a 28.8 kD homodimeric glycoprotein. The predicted N-terminal amino acid is Met.
2 µg/$272; 10 µg/$352
BMP7 Protein - Active Bone Morphogenetic Protein 7 (BMP7) by WB
Select
E. coli
His, N-Terminal
16.9kDa
10 µg/$325; 50 µg/$717; 200 µg/$1,318; 100 µg/$1,113; 1 mg/$2,588; 500 µg/$2,086; 5 mg/$5,005; 2 mg/$2,780
Select
CHO Cells
None
Biologically active
28.8 kDa
10 µg/$349; 2 µg/$268
Select
E. coli
GST
43.1 kD
20 µg/$323; 1 mg/$1,355; 100 µg/$420
Select
E. coli
His
19.8 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
BMP7 Protein - 12.5% SDS-PAGE of human BMP7 stained with Coomassie Blue
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Wheat Germ Extract
GST
73.15 kDa
10 µg/$479; 25 µg/$670
BMP7 Protein - Recombinant Bone Morphogenetic Protein 7 By SDS-PAGE
Select
E. coli
His-T7
49.7 kDa
10 µg/$282; 50 µg/$447; 100 µg/$715; 200 µg/$892; 1 mg/$2,005; 500 µg/$1,543; 5 mg/$3,123; 2 mg/$2,192
BMP7 Protein - Recombinant Bone Morphogenetic Protein 7 By SDS-PAGE
Select
E. coli
His-T7
35.1 kDa
10 µg/$289; 50 µg/$492; 100 µg/$785; 200 µg/$982; 1 mg/$2,119; 500 µg/$1,646; 5 mg/$3,431; 2 mg/$2,309
BMP7 Protein - Recombinant Bone Morphogenetic Protein 7 By SDS-PAGE
Select
E. coli
His
16.9 kDa
10 µg/$293; 50 µg/$517; 100 µg/$827; 200 µg/$1,026; 1 mg/$2,182; 500 µg/$1,702; 5 mg/$3,613; 2 mg/$2,373
BMP7 Protein - Recombinant Bone Morphogenetic Protein 7 By SDS-PAGE
Select
E. coli
His
16.9 kDa
10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).