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BAFF Receptor / CD268

tumor necrosis factor receptor superfamily, member 13C

B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival.

Gene Name: tumor necrosis factor receptor superfamily, member 13C
Family/Subfamily: TNF Receptor , Not assigned-TNF Receptor
Synonyms: TNFRSF13C, BAFFR, BR3, BAFF receptor, BLyS receptor 3, CD268, CD268 antigen, CVID4, BAFF-R, BROMIX
Target Sequences: NM_052945 NP_443177.1 Q96RJ3

☰ Filters
Products
Proteins (20)
Over-Expression Lysate (2)
Recombinant (18)
BAFF Receptor / CD268 (20)
No (20)
Fc (1)
Fc, C-terminus (3)
GST (1)
His (2)
His,C-terminus (1)
His-GST (4)
Human IgG1 Fc (1)
Myc-DDK (Flag) (2)
Chicken (1)
Human (11)
Mouse (3)
Rat (4)
293T Cells (1)
E. coli (10)
HEK 293 Cells (4)
Human (3)
Human Cells (1)
Wheat Germ Extract (1)
Purified (5)
Low endotoxin level (9)
Biologically active (5)
BAFF Receptor / CD268 Protein - 12.5% SDS-PAGE of human TNFRSF13C stained with Coomassie Blue
Select
Wheat Germ Extract
GST
45.3 kDa
10 µg/$479; 25 µg/$670
Select
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
7.7 kDa
10 µg/$268; 50 µg/$349
BAFF Receptor / CD268 Protein
Select
E. coli
None
Biologically active
7.8 kDa
10 µg/$282; 100 µg/$503; 500 µg/$1,058
BAFF Receptor / CD268 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
18.7 kDa
20 µg/$150
BAFF Receptor / CD268 Protein - Eukaryotic B-Cell Activating Factor By SDS-PAGE
Select
Human
None
43.9kDa
50 µg/$752; 10 µg/$331; 200 µg/$1,365; 100 µg/$1,156; 1 mg/$2,648; 500 µg/$2,144; 5 mg/$5,251; 2 mg/$2,838
BAFF Receptor / CD268 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
18.7 kDa
100 µg/$494
Select
E. coli
None
Biologically active
Less than 1 EU/µg (determined by LAL method).
7.8 kDa
1 mg/$1,526; 50 µg/$372
BAFF Receptor / CD268 Protein - Recombinant Human BAFFR/TNFRSF13C (C-Fc)
Select
Human
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
33.4 kDa
10 µg/$290; 50 µg/$446
BAFF Receptor / CD268 Protein - Recombinant Mouse BAFFR/TNFRSF13C (C-Fc)
Select
Human
Fc, C-terminus
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
33.8 kDa
10 µg/$283; 50 µg/$428
Select
HEK 293 Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
8.3 kDa
100 µg/$721
BAFF Receptor / CD268 Protein - The ED50 was determined by the dose-dependent proliferation of Raji cells and was found to be <0.5ng/mL.
Select
E. coli
None
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
~9 kDa
50 µg/$310; 100 µg/$413; 1 mg/$1,458
Select
HEK 293 Cells
Human IgG1 Fc
Less than 0.01 EU/µg protein (determined by LAL method).
~40kDa (SDS-PAGE)
50 µg/$316
Select
Human Cells
Fc
Less than 1.0 EU/µg protein (determined by LAL method).
33.8 kDa
100 µg/$721
Select
HEK 293 Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
33.7 kDa
100 µg/$721
BAFF Receptor / CD268 Protein - Recombinant B-Cell Activation Factor Receptor By SDS-PAGE
Select
E. coli
His-GST
44.6 kDa
10 µg/$288; 50 µg/$487; 100 µg/$780; 200 µg/$972; 1 mg/$2,109; 500 µg/$1,636; 5 mg/$3,403; 2 mg/$2,298
BAFF Receptor / CD268 Protein - Recombinant B-Cell Activation Factor Receptor By SDS-PAGE
Select
E. coli
His-GST
41.2 kDa
10 µg/$265; 50 µg/$347; 100 µg/$545; 200 µg/$682; 1 mg/$1,690; 500 µg/$1,270; 5 mg/$2,637; 2 mg/$1,866
BAFF Receptor / CD268 Protein - Recombinant B-Cell Activation Factor Receptor By SDS-PAGE
Select
E. coli
His
10.8 kDa
10 µg/$265; 50 µg/$347; 100 µg/$545; 200 µg/$682; 1 mg/$1,690; 500 µg/$1,270; 5 mg/$2,637; 2 mg/$1,866
Select
E. coli
His
14.9 kDa
10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
BAFF Receptor / CD268 Protein - Recombinant B-Cell Activation Factor Receptor By SDS-PAGE
Select
E. coli
His-GST
51.0 kDa
10 µg/$277; 50 µg/$420; 100 µg/$670; 200 µg/$837; 1 mg/$1,928; 500 µg/$1,474; 5 mg/$2,927; 2 mg/$2,113
BAFF Receptor / CD268 Protein - Recombinant B-Cell Activation Factor Receptor By SDS-PAGE
Select
E. coli
His-GST
48.6 kDa
10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).