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ARTN / Artemin

artemin

ARTN / Artemin is a member of the glial cell line-derived neurotophic factor (GDNF) family of ligands which are a group of ligands within the TGF-beta superfamily of signaling molecules. GDNFs are unique in having neurotrophic properties and have potential use for gene therapy in neurodegenerative disease. Artemin has been shown in culture to support the survival of a number of peripheral neuron populations and at least one population of dopaminergic CNS neurons. Its role in the PNS and CNS is further substantiated by its expression pattern in the proximity of these neurons. This protein is a ligand for the RET receptor and uses GFR-alpha 3 as a coreceptor. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Name: artemin
Family/Subfamily: TGF beta , not assigned-TGF beta
Synonyms: ARTN, ENOVIN, EVN, Neurotrophic factor, Artemin, Neublastin
Target Sequences: NM_003976 NP_003967.2 Q5T4W7

☰ Filters
Products
Proteins (16)
Over-Expression Lysate (6)
Recombinant (9)
ARTN / Artemin (16)
No (16)
10His, N-terminus + Myc, C-terminus (1)
GST (1)
His, N-Terminal (1)
His-GST, N-terminus (1)
His-T7 (1)
Myc-DDK (Flag) (6)
Human (10)
Mouse (1)
Rat (2)
293T Cells (3)
E. coli (9)
HEK 293 Cells (3)
Wheat Germ Extract (1)
Purified (5)
Low endotoxin level (5)
Biologically active (1)
ARTN / Artemin Protein - Recombinant Artemin By SDS-PAGE
Select
E. coli
His, N-Terminal
13.6 kDa
10 µg/$267; 50 µg/$352; 100 µg/$562; 200 µg/$702; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900
ARTN / Artemin Protein - Recombinant Artemin By SDS-PAGE
Select
E. coli
His-T7
15.9 kDa
10 µg/$271; 50 µg/$382; 100 µg/$610; 200 µg/$762; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998
Select
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
24.2 kDa
5 µg/$268; 20 µg/$349
ARTN / Artemin Protein - 12.5% SDS-PAGE of human ARTN stained with Coomassie Blue
Select
Wheat Germ Extract
GST
50 kDa
2 µg/$439
ARTN / Artemin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
23.62 kDa
20 µg/$150
ARTN / Artemin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
18.8 kDa
20 µg/$150
ARTN / Artemin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
18.8 kDa
20 µg/$150
Select
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
12.1kD
10 µg/$277; 50 µg/$395; 500 µg/$1,585; 1 mg/$2,157
ARTN / Artemin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
23.62 kDa
100 µg/$494
ARTN / Artemin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
18.8 kDa
100 µg/$494
ARTN / Artemin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
18.8 kDa
100 µg/$494
Select
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
~12.2 kDa
20 µg/$395; 1 mg/$4,915
Select
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
12.1 kDa
10 µg/$277; 50 µg/$389
ARTN / Artemin Protein - Recombinant Artemin (ARTN) by SDS-PAGE
Select
E. coli
His-GST, N-terminus
42.0kDa
10 µg/$267; 50 µg/$352; 200 µg/$702; 100 µg/$562; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,838
Select
E. coli
None
Less than 0.1 ng/µg protein.
27.0 kDa
2 µg/$338; 10 µg/$427; 1000 µg/$5,320
ARTN / Artemin Protein - Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of Recombinant Rat Artemin(Artn) could indicate that this peptide derived from E.coli-expressed Rattus norvegicus (Rat) Artn.
Select
E. coli
10His, N-terminus + Myc, C-terminus
17.1 kDa
20 µg/$405; 1 mg/$1,679; 100 µg/$598
Viewing 1-16 of 16 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).