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APLNR/ Apelin Receptor / APJ

apelin receptor

Receptor for apelin coupled to G proteins that inhibit adenylate cyclase activity and plays a role in various processes in adults such as regulation of blood pressure, heart contractility, and heart failure. Also plays a key role in early development such as gastrulation and heart morphogenesis by acting as a receptor for APELA hormone. Alternative coreceptor with CD4 for HIV-1 infection; may be involved in the development of AIDS dementia.

Gene Name: apelin receptor
Family/Subfamily: GPCR , Apelin
Synonyms: APLNR, AGTRL1, Angiotensin receptor-like 1, Angiotensin II receptor-like 1, Apelin receptor, APJ, APJ (apelin) receptor, APJR, G protein-coupled receptor APJ, HG11 orphan receptor, HG11, APJ receptor, G-protein coupled receptor APJ
Target Sequences: NM_005161 NP_005152.1 P35414

Publications (2)

1
The endogenous peptide apelin potently improves cardiac contractility and reduces cardiac loading in vivo. Ashley EA, Powers J, Chen M, Kundu R, Finsterbach T, Caffarelli A, Deng A, Eichhorn J, Mahajan R, Agrawal R, Greve J, Robbins R, Patterson AJ, Bernstein D and Quertermous T. Cardiovascular research. 2005 65:73-82. (IHC-P; Mouse, Human) [PubMed:15621035] [PMC:PMC2517138]
2
Apelin retards the progression of diabetic nephropathy. Day RT, Cavaglieri RC, Feliers D. American journal of physiology. Renal physiology. 2013 Mar;304:F788-800. [Full Text Article] [PubMed:23303408] [PMC:PMC3602700] Related Antibodies: LS-A64.

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Products
Antibodies (40)
Primary (40)
APLNR/ Apelin Receptor / APJ (40)
Human (36)
Mouse (10)
Rat (7)
Bat (3)
Chicken (1)
Chimpanzee (3)
Gibbon (6)
Guinea pig (3)
Hamster (7)
Horse (4)
Monkey (4)
Orangutan (3)
Rabbit (3)
IHC (18)
IHC-P (11)
WB (28)
ELISA (21)
IF (4)
IP (1)
Peptide-ELISA (2)
rabbit (40)
Product Group
GPCR Database Antibodies (3)
IHCPlus (4)
PathPlus Neuro (3)
IgG (25)
polyclonal pc (40)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (6)
CF Conjugated (1)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (1)
Preservative Free (3)
Unconjugated (23)
aa215-244 (7)
C-Terminus (4)
aa46-95 (4)
aa357-377 (3)
Cytoplasmic Domain (2)
Internal Region (2)
110-190 aa, Internal (1)
Extracellular Domain (1)
Internal (1)
aa132-181 (1)
aa310-380 (1)
No (39)
Yes (1)
APLNR/ Apelin Receptor / APJ Antibody - Anti-Apelin Receptor antibody IHC staining of human brain, astrocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Neuroscience
APLNR/ Apelin Receptor / APJ Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Mouse, Human
IHC, IHC-P
Unconjugated
50 µg/$460
APLNR/ Apelin Receptor / APJ Antibody - Anti-APLNR/ Apelin Receptor / APJ antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Neuroscience
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APLNR/ Apelin Receptor / APJ Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$460
APLNR/ Apelin Receptor / APJ Antibody - Anti-Apelin Receptor antibody IHC of human brain, astrocyte. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Neuroscience
Fast Shipping
APLNR/ Apelin Receptor / APJ Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Hamster, Horse, Human
IHC, IHC-P
Unconjugated
50 µg/$440
APLNR/ Apelin Receptor / APJ Antibody - Anti-Apelin Receptor / APJ antibody IHC of human spleen endothelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5-10 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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APLNR/ Apelin Receptor / APJ Rabbit anti-Mouse Polyclonal (C-Terminus) Antibody
Mouse
IHC, IHC-P, WB
Unconjugated
50 µl/$460
APLNR/ Apelin Receptor / APJ Antibody - Anti-Apelin Receptor / APJ antibody IHC of human spleen endothelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5-10 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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APLNR/ Apelin Receptor / APJ Rabbit anti-Mouse Polyclonal (C-Terminus) (HRP) Antibody
Rabbit, Mouse, Hamster, Orangutan, Gibbon, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
APLNR/ Apelin Receptor / APJ Antibody - Anti-Apelin Receptor / APJ antibody IHC of human spleen endothelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5-10 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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APLNR/ Apelin Receptor / APJ Rabbit anti-Mouse Polyclonal (C-Terminus) (Biotin) Antibody
Rabbit, Mouse, Hamster, Orangutan, Gibbon, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
APLNR/ Apelin Receptor / APJ Antibody - Anti-Apelin Receptor / APJ antibody IHC of human spleen endothelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5-10 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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APLNR/ Apelin Receptor / APJ Rabbit anti-Mouse Polyclonal (C-Terminus) (FITC) Antibody
Rabbit, Mouse, Hamster, Orangutan, Gibbon, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
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APLNR/ Apelin Receptor / APJ Rabbit anti-Rat Polyclonal (Internal Region) (Preservative Free) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated, Preservative Free
20 µg/$242; 100 µg/$304; 200 µg/$334; 500 µg/$452
APLNR/ Apelin Receptor / APJ Antibody - Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
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APLNR/ Apelin Receptor / APJ Rabbit anti-Human Polyclonal (110-190 aa, Internal) Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$460
APLNR/ Apelin Receptor / APJ Antibody - Anti-APLNR/ Apelin Receptor / APJ antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
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APLNR/ Apelin Receptor / APJ Rabbit anti-Human Polyclonal (aa132-181) Antibody
Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
APLNR/ Apelin Receptor / APJ Antibody - Sample (30 ug of whole cell lysate). A: H1299. 10% SDS PAGE. Apelin receptor antibody. APLNR antibody diluted at 1:1000.
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APLNR/ Apelin Receptor / APJ Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µl/$402
APLNR/ Apelin Receptor / APJ Antibody - Immunohistochemistry of paraffin-embedded Human thyroid cancer using APLNR Polyclonal Antibody at dilution of 1:50.
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APLNR/ Apelin Receptor / APJ Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
APLNR/ Apelin Receptor / APJ Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
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APLNR/ Apelin Receptor / APJ Rabbit anti-Human Polyclonal (aa310-380) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$460
APLNR/ Apelin Receptor / APJ Antibody - Immunohistochemistry of paraffin-embedded human colon cancer tissue using antibody at 1:100 dilution.
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APLNR/ Apelin Receptor / APJ Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
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APLNR/ Apelin Receptor / APJ Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, IHC
HRP Conjugated
50 µg/$294; 100 µg/$360
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APLNR/ Apelin Receptor / APJ Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, IHC
Biotin Conjugated
50 µg/$294; 100 µg/$360
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APLNR/ Apelin Receptor / APJ Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, IHC
FITC Conjugated
50 µg/$294; 100 µg/$360
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APLNR/ Apelin Receptor / APJ Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
APLNR/ Apelin Receptor / APJ Antibody - Peptide - + Immunofluorescence analysis of MCF-7 cells, using AGTRL1 antibody.
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APLNR/ Apelin Receptor / APJ Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, WB
Unconjugated
100 µg/$357
APLNR/ Apelin Receptor / APJ Antibody - Staining 293 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
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APLNR/ Apelin Receptor / APJ Rabbit anti-Human Polyclonal Antibody
Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
APLNR/ Apelin Receptor / APJ Antibody - Immunohistochemistry of paraffin-embedded Human colon cancer using APLNR Polyclonal Antibody at dilution of 1:40.
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APLNR/ Apelin Receptor / APJ Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
APLNR/ Apelin Receptor / APJ Antibody - Western blot analysis of extracts of U87 cells.
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APLNR/ Apelin Receptor / APJ Rabbit anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
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APLNR/ Apelin Receptor / APJ Rabbit anti-Human Polyclonal (aa215-244) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
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APLNR/ Apelin Receptor / APJ Rabbit anti-Human Polyclonal (aa215-244) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
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APLNR/ Apelin Receptor / APJ Rabbit anti-Human Polyclonal (aa215-244) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).