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| Catalog Number | Size | Price |
|---|---|---|
| LS-A64-50 | 50 µg (1 mg/ml) | $460 |
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PathPlus™ Polyclonal Rabbit anti‑Human APLNR/ Apelin Receptor / APJ Antibody (Cytoplasmic Domain, IHC) LS‑A64
PathPlus™ Polyclonal Rabbit anti‑Human APLNR/ Apelin Receptor / APJ Antibody (Cytoplasmic Domain, IHC) LS‑A64
Antibody:
APLNR/ Apelin Receptor / APJ Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Mouse
Format:
Unconjugated, Unmodified
Overview
Antibody:
APLNR/ Apelin Receptor / APJ Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Mouse
Format:
Unconjugated, Unmodified
Specifications
Description
Apelin receptor (APLNR) inhibits adenylate cyclase activity and plays a role in various processes in adults such as regulation of blood pressure, heart contractility, and heart failure. It also plays a key role in early development such as gastrulation and heart morphogenesis by acting as a receptor for APELA hormone. APLNR is an alternative coreceptor with CD4 for HIV-1 infection and it may be involved in the development of AIDS-related dementia.
References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human APLNR/ Apelin Receptor / APJ
Synonyms
APLNR | AGTRL1 | Angiotensin receptor-like 1 | Angiotensin II receptor-like 1 | Apelin receptor | APJ | APJ (apelin) receptor | APJR | G protein-coupled receptor APJ | HG11 orphan receptor | HG11 | APJ receptor | G-protein coupled receptor APJ
Host
Rabbit
Reactivity
Human, Mouse
(tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 20 amino acid peptide from 3rd cytoplasmic domain of human Apelin Receptor. Percent identity with other species by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Panda, Bat, Horse, Rabbit (100%); Elephant (95%); Platypus (90%).
Epitope
Cytoplasmic Domain
Specificity
Human Apelin Receptor. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Applications
- IHC
- IHC - Paraffin (20 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About APLNR/ Apelin Receptor / APJ
Validation
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
lymph node, Hodgkin's lymphoma
lymph node, Hodgkin's lymphoma
Anti-Apelin Receptor antibody IHC staining of human brain, astrocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-Apelin Receptor antibody IHC staining of human brain, astrocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-APLNR/ Apelin Receptor / APJ antibody IHC of human brain vessel. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-APLNR/ Apelin Receptor / APJ antibody IHC of human brain vessel. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
See More About...
LSBio Ratings
PathPlus™ APLNR/ Apelin Receptor / APJ Antibody (Cytoplasmic Domain) for IHC LS-A64 has an LSBio Rating of
Publications (4)
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (1)
Apelin retards the progression of diabetic nephropathy. Day RT, Cavaglieri RC, Feliers D. American journal of physiology. Renal physiology. 2013 Mar;304:F788-800.
Customer Reviews (0)
Featured Products
Species:
Human, Hamster, Horse
Applications:
IHC, IHC - Paraffin
Species:
Human, Monkey
Applications:
IHC, IHC - Paraffin
Species:
Human, Monkey
Applications:
IHC, IHC - Paraffin
Species:
Human, Hamster, Horse
Applications:
IHC, IHC - Paraffin
Species:
Rat, Human, Mouse
Applications:
Western blot, ELISA
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/22/2024
Date Requested: 11/22/2024
