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AMIGO2

adhesion molecule with Ig-like domain 2

AMIGO2/ALIVIN-1 is a member of a small family of type I membrane proteins containing six leucine rich repeats (LRR), one immunoglobulin domain and cysteine rich LLR -NH2 and -COOH domains. In assays a substrate bound form of AMIGO2 promoted prominent neurite extension and inhibited fasciculation of neurites. A homophilic and heterophilic binding mechanism exists between members of the AMIGO family. AMIGOs are thought to be novel cell adhesion molecules expressed on fiber tracts of neuronal tissues that participate in their formation.

Gene Name: adhesion molecule with Ig-like domain 2
Synonyms: AMIGO2, ALI1, Alivin 1, Alivin-1, Alvin 1, AMIGO-2, Amphoterin induced gene 2, Amphoterin-induced protein 2, Transmembrane protein AMIGO2, DEGA
Target Sequences: NM_181847 NP_862830.1 Q86SJ2

Publications (2)

1
Altered Gene Expression Profiles in the Lungs of Streptozotocin-induced Diabetic Mice. Jung-Hyun Kim, Roya Rasaei, Sujin Park, Ji-Young Kim, Sunghun Na, Seok-Ho Hong. Development & reproduction. 2020 September;24:197-205. [Full Text Article] [PubMed:33110951] [PMC:PMC7576965] Related Antibodies: LS-C404504.
2
Establishment of an antibody specific for AMIGO2 improves immunohistochemical evaluation of liver metastases and clinical outcomes in patients with colorectal cancer. Keisuke Goto, Mitsuhiko Osaki, Runa Izutsu, Hiroshi Tanaka, Ryo Sasaki, Akimitsu Tanio, Hiroyuki Satofuka, Yasuhiro Kazuki, Manabu Yamamoto, Hiroyuki Kugoh, Hisao Ito, Mitsuo Oshimura, Yoshiyuki Fujiwara, Futoshi Okada. Diagnostic pathology. 2022 January;17:16. [Full Text Article] [PubMed:35094710] [PMC:PMC8802484] Related Antibodies: LS-C404504.

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Products
Antibodies (26)
Primary (26)
AMIGO2 (26)
Human (25)
Mouse (9)
Rat (10)
Bat (3)
Bovine (3)
Chimpanzee (3)
Dog (3)
Gibbon (6)
Hamster (6)
Monkey (3)
Orangutan (6)
Pig (3)
Rabbit (3)
IHC (4)
IHC-P (3)
WB (20)
ELISA (16)
IF (2)
rabbit (25)
mouse (1)
Product Group
IHCPlus (1)
IgG (16)
polyclonal pc (26)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (4)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (1)
Unconjugated (12)
aa435-465 (6)
aa290-339 (4)
aa75-124 (4)
C-Terminus (1)
No (25)
Yes (1)
AMIGO2 Antibody - Immunohistochemistry of paraffin-embedded Human colon cancer using AMIGO2 Polyclonal Antibody at dilution of 1:50.
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AMIGO2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
AMIGO2 Antibody - Immunohistochemistry of paraffin-embedded Human esophagus cancer using AMIGO2 Polyclonal Antibody at dilution of 1:50.
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AMIGO2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
AMIGO2 Antibody - Immunohistochemistry Dilution at 1:800 and staining in paraffin-embedded human prostate cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal Goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated Secondary antibody and visualized using an HRP conjugated SP system.
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AMIGO2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
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AMIGO2 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
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AMIGO2 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
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AMIGO2 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
AMIGO2 Antibody - Human Breast: Formalin-Fixed, Paraffin-Embedded (FFPE)
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AMIGO2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$460
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AMIGO2 Rabbit anti-Human Polyclonal (aa435-465) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
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AMIGO2 Rabbit anti-Human Polyclonal (aa435-465) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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AMIGO2 Rabbit anti-Human Polyclonal (aa435-465) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
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AMIGO2 Rabbit anti-Human Polyclonal (aa435-465) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
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AMIGO2 Rabbit anti-Human Polyclonal (aa435-465) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
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AMIGO2 Rabbit anti-Human Polyclonal (aa435-465) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
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AMIGO2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$341
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AMIGO2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
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AMIGO2 Mouse anti-Human Polyclonal Antibody
Human
IF, WB
Unconjugated
50 µg/$705
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AMIGO2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
100 µl/$412
AMIGO2 Antibody - Western blot of Human RPMI-8226. AMIGO2 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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AMIGO2 Rabbit anti-Human Polyclonal (aa75-124) Antibody
Human
WB
Unconjugated
100 µl/$424
AMIGO2 Antibody - Western blot of Human RPMI-8226. AMIGO2 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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AMIGO2 Rabbit anti-Human Polyclonal (aa75-124) (HRP) Antibody
Rat, Hamster, Mouse, Human, Chimpanzee, Orangutan, Gibbon
WB
HRP Conjugated
100 µl/$469
AMIGO2 Antibody - Western blot of Human RPMI-8226. AMIGO2 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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AMIGO2 Rabbit anti-Human Polyclonal (aa75-124) (Biotin) Antibody
Rat, Hamster, Mouse, Human, Chimpanzee, Orangutan, Gibbon
WB
Biotin Conjugated
100 µl/$469
AMIGO2 Antibody - Western blot of Human RPMI-8226. AMIGO2 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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AMIGO2 Rabbit anti-Human Polyclonal (aa75-124) (FITC) Antibody
Rat, Hamster, Mouse, Human, Chimpanzee, Orangutan, Gibbon
WB
FITC Conjugated
100 µl/$469
AMIGO2 Antibody - Immunochemical staining of human AMIGO2 in human kidney with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.
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AMIGO2 Rabbit anti-Human Polyclonal Antibody
Human
IHC-P
Unconjugated
100 µl/$412
AMIGO2 Antibody - AMIGO2 antibody Western blot of Rat Heart lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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AMIGO2 Rabbit anti-Rat Polyclonal (aa290-339) Antibody
Rat
WB
Unconjugated
100 µl/$424
AMIGO2 Antibody - AMIGO2 antibody Western blot of Rat Heart lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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AMIGO2 Rabbit anti-Rat Polyclonal (aa290-339) (Biotin) Antibody
Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Pig, Bat, Gibbon, Orangutan, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
AMIGO2 Antibody - AMIGO2 antibody Western blot of Rat Heart lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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AMIGO2 Rabbit anti-Rat Polyclonal (aa290-339) (FITC) Antibody
Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Pig, Bat, Gibbon, Orangutan, Human, Monkey
WB
FITC Conjugated
100 µl/$469
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).