ALOX12 / 12 Lipoxygenase

arachidonate 12-lipoxygenase

Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Mainly converts arachidonic acid to (12S)-hydroperoxyeicosatetraenoic acid/(12S)-HPETE but can also metabolize linoleic acid. Has a dual activity since it also converts leukotriene A4/LTA4 into both the bioactive lipoxin A4/LXA4 and lipoxin B4/LXB4. Through the production of specific bioactive lipids like (12S)-HPETE it regulates different biological processes including platelet activation. It also probably positively regulates angiogenesis through regulation of the expression of the vascular endothelial growth factor. Plays a role in apoptotic process, promoting the survival of vascular smooth muscle cells for instance. May also play a role in the control of cell migration and proliferation.

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Products

Antibodies (36)

Type

Primary (36)

Target

ALOX12 / 12 Lipoxygenase (36)

Reactivity

Human (36)

Mouse (3)

Rat (3)

Chimpanzee (3)

Gibbon (3)

Monkey (3)

Application

IHC (7)

IHC-P (3)

WB (29)

Flo (1)

ELISA (5)

IF (4)

Host

rabbit (28)

mouse (8)

Product Group

IHCPlus (1)

Isotype

IgG (19)

IgG1 (4)

IgG2a (2)

IgG2a,k (1)

Clonality

monoclonal mc (7)

polyclonal pc (29)

Clone

2D10 (1)

OTI1B2 (2)

OTI1C3 (2)

OTI5H2 (2)

Format

APC (1)

APC Conjugated (2)

Biotin Conjugated (4)

Carrier-free (3)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (4)

HRP Conjugated (4)

PE Conjugated (2)

Unconjugated (18)

Epitope

aa352-656 (8)

aa578-627 (4)

aa609-628 (1)

aa618-650 (1)

Publications

No (36)

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IHC-plus™ ALOX12 / 12 Lipoxygenase Antibody (aa618-650) LS-B10714

(4.0) Rating

Antibody:

ALOX12 / 12 Lipoxygenase Rabbit anti-Human Polyclonal (aa618-650) Antibody

Reactivity:

Human

Applications:

Flo, IF, IHC-P, WB

Format:

Unconjugated

Price:

200 µl/$460

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ALOX12 / 12 Lipoxygenase Antibody (aa578-627) LS-C81851

Antibody:

ALOX12 / 12 Lipoxygenase Rabbit anti-Human Polyclonal (aa578-627) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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ALOX12 / 12 Lipoxygenase Antibody LS-C833341

Antibody:

ALOX12 / 12 Lipoxygenase Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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ALOX12 / 12 Lipoxygenase Antibody LS-C306215

Antibody:

ALOX12 / 12 Lipoxygenase Mouse anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IF, WB

Format:

Unconjugated

Price:

50 µg/$705

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ALOX12 / 12 Lipoxygenase Antibody (clone OTI1B2) LS-C794119

Antibody:

ALOX12 / 12 Lipoxygenase Mouse anti-Human Monoclonal (OTI1B2) Antibody

Reactivity:

Human

Applications:

IHC

Format:

Unconjugated

Price:

100 µl/$434

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ALOX12 / 12 Lipoxygenase Antibody (clone OTI1B2, Carrier-free) LS-C791373

Antibody:

ALOX12 / 12 Lipoxygenase Mouse anti-Human Monoclonal (Carrier-free) (OTI1B2) Antibody

Reactivity:

Human

Applications:

IHC

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

ALOX12 / 12 Lipoxygenase Antibody LS-C749685

Antibody:

ALOX12 / 12 Lipoxygenase Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

Select

ALOX12 / 12 Lipoxygenase Antibody LS-C680154

Antibody:

ALOX12 / 12 Lipoxygenase Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

Select

ALOX12 / 12 Lipoxygenase Antibody (HRP) LS-C680156

Antibody:

ALOX12 / 12 Lipoxygenase Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

Select

ALOX12 / 12 Lipoxygenase Antibody (Biotin) LS-C680155

Antibody:

ALOX12 / 12 Lipoxygenase Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

Select

ALOX12 / 12 Lipoxygenase Antibody (FITC) LS-C680157

Antibody:

ALOX12 / 12 Lipoxygenase Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

ALOX12 / 12 Lipoxygenase Antibody (clone OTI1C3) LS-C340376

Antibody:

ALOX12 / 12 Lipoxygenase Mouse anti-Human Monoclonal (OTI1C3) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$434

Select

ALOX12 / 12 Lipoxygenase Antibody (clone OTI1C3, Carrier-free) LS-C799600

Antibody:

ALOX12 / 12 Lipoxygenase Mouse anti-Human Monoclonal (Carrier-free) (OTI1C3) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

ALOX12 / 12 Lipoxygenase Antibody (clone 2D10) LS-C196646

Antibody:

ALOX12 / 12 Lipoxygenase Mouse anti-Human Monoclonal (2D10) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$423

Select

ALOX12 / 12 Lipoxygenase Antibody (clone OTI5H2) LS-C340386

Antibody:

ALOX12 / 12 Lipoxygenase Mouse anti-Human Monoclonal (OTI5H2) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$434

Select

ALOX12 / 12 Lipoxygenase Antibody (clone OTI5H2, Carrier-free) LS-C791386

Antibody:

ALOX12 / 12 Lipoxygenase Mouse anti-Human Monoclonal (Carrier-free) (OTI5H2) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

ALOX12 / 12 Lipoxygenase Antibody LS-C309424

Antibody:

ALOX12 / 12 Lipoxygenase Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$749

Select

ALOX12 / 12 Lipoxygenase Antibody (HRP) LS-C540839

Antibody:

ALOX12 / 12 Lipoxygenase Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$937

Select

ALOX12 / 12 Lipoxygenase Antibody (Biotin) LS-C520707

Antibody:

ALOX12 / 12 Lipoxygenase Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$937

Select

ALOX12 / 12 Lipoxygenase Antibody (FITC) LS-C530751

Antibody:

ALOX12 / 12 Lipoxygenase Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$937

Select

ALOX12 / 12 Lipoxygenase Antibody (APC) LS-C512492

Antibody:

ALOX12 / 12 Lipoxygenase Rabbit anti-Human Polyclonal (APC) Antibody

Reactivity:

Human

Applications:

WB

Format:

APC Conjugated

Price:

100 µl/$937

• Unconjugated
• HRP
• Biotin
• FITC
• APC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • APC

Select

ALOX12 / 12 Lipoxygenase Antibody (aa609-628) LS-C392516

Antibody:

ALOX12 / 12 Lipoxygenase Rabbit anti-Human Polyclonal (aa609-628) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$575

Select

ALOX12 / 12 Lipoxygenase Antibody (aa352-656) LS-C314862

Antibody:

ALOX12 / 12 Lipoxygenase Rabbit anti-Human Polyclonal (aa352-656) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$303; 200 µl/$343; 500 µl/$476; 1 ml/$543; 2 ml/$715; 5 ml/$1,182

Select

ALOX12 / 12 Lipoxygenase Antibody LS-C662147

Antibody:

ALOX12 / 12 Lipoxygenase Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

Select

ALOX12 / 12 Lipoxygenase Antibody LS-C782971

Antibody:

ALOX12 / 12 Lipoxygenase Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$575

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