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Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
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Customer Service: (800) 227-6666 / (650) 697-3600
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Adiponectin
adiponectin, C1Q and collagen domain containing
Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.
| Gene Name: | adiponectin, C1Q and collagen domain containing |
| Synonyms: | ADIPOQ, Adiponectin, ADPN, ACDC, ADIPQTL1, APM-1, APM1, ACRP30, Gelatin-binding protein 28, GBP28, Gelatin-binding protein |
| Target Sequences: | NM_004797 NP_004788.1 Q15848 |
Publications (2)
1
Expression of adiponectin receptors and effects of adiponectin isoforms in mouse preimplantation embryos. iko, Burku J, Bukovsk A, Fabian D, Rehk P, Koppel J. Human reproduction (Oxford, England). 2010 25:2247-55. (IHC; Mouse)
[PubMed:20663797]
Related Antibodies: LS-B440.
2
5-Hydroxytryptophan Suppresses the Abdominal Fat Deposit and Is Beneficial to the Intestinal Immune Function in Broilers. Hui Wang, Shaoqiong Liu, Jun Li, Liyuan Wang, Xiaojuan Wang, Jingpeng Zhao, Hongchao Jiao, Hai Lin. Frontiers in physiology. 2020 July;11:655. [Full Text Article]
[PubMed:32595527]
[PMC:PMC7304481]
Related Antibodies: LS-C292655.
☰ Filters
Products
Proteins
(50)
Type
Over-Expression Lysate
(4)
Recombinant
(46)
Target
Adiponectin
(50)
Publications
No
(50)
Tag
6His, C-terminus
(4)
6His, N-terminus
(5)
DDK (Flag)
(2)
DDK,C-terminus
(3)
DDK,N-terminus
(1)
GST, N-terminus
(1)
His
(10)
His, N-Terminal
(1)
His, N-terminus
(1)
His-GST
(3)
His-S
(1)
His-SUMO
(1)
His-T7
(1)
Myc-DDK (Flag)
(5)
Species
Bovine
(3)
Chicken
(1)
Dog
(1)
Human
(23)
Mouse
(16)
Pig
(1)
Rat
(3)
Source
293T Cells
(2)
CHO Cells
(2)
E. coli
(27)
HEK 293 Cells
(8)
High Five Cells
(2)
Human Cells
(2)
Mammalian Cells
(2)
Sf9 Cells
(2)
Wheat Germ Extract
(1)
Yeast
(1)
Purification
Purified
(15)
Low Endotoxin Level
Low endotoxin level
(25)
Biologically Active
Biologically active
(10)
HEK 293 Cells
None
Biologically active
Less than 0.2 EU/µg protein (determined by LAL method).
16~17 kDa (SDS-PAGE)
50 µg/$402; 10 µg/$278; 1 mg/$2,653
Yeast
6His, N-terminus
26.4 kD
100 µg/$679; 20 µg/$429; 1 mg/$1,973
E. coli
None
Biologically active
Less than 0.2 EU/µg protein (determined by LAL method).
24.6 kDa (SDS-PAGE)
50 µg/$402; 10 µg/$278; 1 mg/$2,653
High Five Cells
His
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
31-36 kDa
5 µg/$268; 25 µg/$349
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
100 µg/$317; 500 µg/$526; 20 µg/$245
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
18.1 kDa
5 µg/$268; 25 µg/$349
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
16.6 kDa
5 µg/$268; 25 µg/$349
High Five Cells
His
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
35.0 kDa
5 µg/$268; 25 µg/$349
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
16.6 kDa
5 µg/$268; 25 µg/$349
E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
E. coli
His-GST
47.9 kDa
50 µg/$392; 10 µg/$273; 200 µg/$782; 100 µg/$625; 1 mg/$1,847; 500 µg/$1,404; 5 mg/$2,807; 2 mg/$2,029
E. coli
His-T7
27.0 kDa
10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
E. coli
His
17.5 kDa
10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
E. coli
His-S
21.3 kDa
10 µg/$267; 50 µg/$352; 100 µg/$562; 200 µg/$702; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900
E. coli
His
17.0 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
E. coli
His-GST
56.7 kDa
10 µg/$286; 50 µg/$472; 100 µg/$752; 200 µg/$942; 1 mg/$2,069; 500 µg/$1,600; 5 mg/$3,291; 2 mg/$2,257
E. coli
6His, N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
27.2kD
10 µg/$281; 50 µg/$395; 500 µg/$1,585; 1 mg/$2,157
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
25.58kD
10 µg/$269; 50 µg/$372; 500 µg/$1,585; 1 mg/$2,157
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
27.6kD
10 µg/$281; 50 µg/$395; 500 µg/$1,585; 1 mg/$2,157
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
HEK 293 Cells
Myc-DDK (Flag)
24.9 kDa
20 µg/$1,107
293T Cells
Myc-DDK (Flag)
26.41 kDa
20 µg/$150
293T Cells
Myc-DDK (Flag)
26.9 kDa
20 µg/$150
HEK 293 Cells
Myc-DDK (Flag)
26.9 kDa
100 µg/$494
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