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Adiponectin

adiponectin, C1Q and collagen domain containing

Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.

Gene Name: adiponectin, C1Q and collagen domain containing
Synonyms: ADIPOQ, Adiponectin, ADPN, ACDC, ADIPQTL1, APM-1, APM1, ACRP30, Gelatin-binding protein 28, GBP28, Gelatin-binding protein
Target Sequences: NM_004797 NP_004788.1 Q15848

Publications (2)

1
Expression of adiponectin receptors and effects of adiponectin isoforms in mouse preimplantation embryos. iko, Burku J, Bukovsk A, Fabian D, Rehk P, Koppel J. Human reproduction (Oxford, England). 2010 25:2247-55. (IHC; Mouse) [PubMed:20663797] Related Antibodies: LS-B440.
2
5-Hydroxytryptophan Suppresses the Abdominal Fat Deposit and Is Beneficial to the Intestinal Immune Function in Broilers. Hui Wang, Shaoqiong Liu, Jun Li, Liyuan Wang, Xiaojuan Wang, Jingpeng Zhao, Hongchao Jiao, Hai Lin. Frontiers in physiology. 2020 July;11:655. [Full Text Article] [PubMed:32595527] [PMC:PMC7304481] Related Antibodies: LS-C292655.

☰ Filters
Products
Proteins (50)
Over-Expression Lysate (4)
Recombinant (46)
Adiponectin (50)
No (50)
6His, C-terminus (4)
6His, N-terminus (5)
DDK (Flag) (2)
DDK,C-terminus (3)
DDK,N-terminus (1)
GST, N-terminus (1)
His (10)
His, N-Terminal (1)
His, N-terminus (1)
His-GST (3)
His-S (1)
His-SUMO (1)
His-T7 (1)
Myc-DDK (Flag) (5)
Bovine (3)
Chicken (1)
Dog (1)
Human (23)
Mouse (16)
Pig (1)
Rat (3)
293T Cells (2)
CHO Cells (2)
E. coli (27)
HEK 293 Cells (8)
High Five Cells (2)
Human Cells (2)
Mammalian Cells (2)
Sf9 Cells (2)
Wheat Germ Extract (1)
Yeast (1)
Purified (15)
Low endotoxin level (25)
Biologically active (10)
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HEK 293 Cells
None
Biologically active
Less than 0.2 EU/µg protein (determined by LAL method).
16~17 kDa (SDS-PAGE)
50 µg/$402; 10 µg/$278; 1 mg/$2,653
Adiponectin Protein
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Yeast
6His, N-terminus
26.4 kD
100 µg/$679; 20 µg/$429; 1 mg/$1,973
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E. coli
None
Biologically active
Less than 0.2 EU/µg protein (determined by LAL method).
24.6 kDa (SDS-PAGE)
50 µg/$402; 10 µg/$278; 1 mg/$2,653
Adiponectin Protein
Select
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
100 µg/$411; 500 µg/$985; 20 µg/$276
Adiponectin Protein - Effect of Adiponectin (rat) (rec.) on the phosphorylation of acetyl-CoA carboxylase (ACC) in C2C12 cells. C2C12 myocytes were treated with 25 ug/ml for 15 minutes after serum starvation for 24 hours. 100 ug per well of total cell lysate was separated on reduced SDS-PAGE gels. Immunoblot analysis was performed to measure phosphorylation of ACC with an anti-phosphoACC antibody. 1: 25 ug/ml of Adiponectin (rat) (rec.). 2: 25 ug/ml of a FLAG-tagged control protein. 3: phosphate-buffered saline.
Select
HEK 293 Cells
DDK (Flag)
Less than 0.1 EU/µg protein (determined by LAL method).
~30kDa (SDS-PAGE)
50 µg/$442
Select
HEK 293 Cells
DDK (Flag)
Less than 0.1 EU/µg protein (determined by LAL method).
~33kDa (SDS-PAGE)
50 µg/$428
Adiponectin Protein
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E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
Adiponectin Protein - Recombinant Adiponectin By SDS-PAGE
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E. coli
His-GST
54.5 kDa
10 µg/$291; 50 µg/$502; 100 µg/$802; 200 µg/$1,002; 1 mg/$2,144; 500 µg/$1,668; 5 mg/$3,501; 2 mg/$2,334
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E. coli
His-SUMO
40.4 kD
1 mg/$1,679; 100 µg/$598; 20 µg/$405
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E. coli
His
29 kD
1 mg/$1,679; 100 µg/$500; 20 µg/$364
Select
CHO Cells
None
Biologically active
Less than 0.2 EU/µg protein (determined by LAL method).
25~28 kDa (SDS-PAGE)
10 µg/$278; 1 mg/$2,653; 50 µg/$402
Adiponectin Protein
Select
E. coli
6His, N-terminus
14 kDa
10 µg/$265; 50 µg/$315; 100 µg/$365
Select
E. coli
None
Biologically active
Less than 0.2 EU/µg protein (determined by LAL method).
16.5 kDa (SDS-PAGE)
50 µg/$364; 10 µg/$278; 1 mg/$1,933
Adiponectin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
26.41 kDa
20 µg/$150
Adiponectin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
26.9 kDa
20 µg/$150
Adiponectin Protein - Recombinant Adiponectin By SDS-PAGE
Select
E. coli
His-GST
56.7 kDa
10 µg/$286; 50 µg/$472; 100 µg/$752; 200 µg/$942; 1 mg/$2,069; 500 µg/$1,600; 5 mg/$3,291; 2 mg/$2,257
Adiponectin Protein - Recombinant Adiponectin By SDS-PAGE
Select
E. coli
His-GST
47.9 kDa
50 µg/$392; 10 µg/$273; 200 µg/$782; 100 µg/$625; 1 mg/$1,847; 500 µg/$1,404; 5 mg/$2,807; 2 mg/$2,029
Adiponectin Protein - Recombinant Adiponectin By SDS-PAGE
Select
E. coli
His-T7
27.0 kDa
10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
Adiponectin Protein - Recombinant Adiponectin By SDS-PAGE
Select
E. coli
His
17.5 kDa
10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
Adiponectin Protein - Recombinant Adiponectin By SDS-PAGE
Select
E. coli
His-S
21.3 kDa
10 µg/$267; 50 µg/$352; 100 µg/$562; 200 µg/$702; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900
Adiponectin Protein - Recombinant Adiponectin By SDS-PAGE
Select
E. coli
His
17.0 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
Select
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
16.6 kDa
5 µg/$268; 25 µg/$349
Select
High Five Cells
His
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
31-36 kDa
5 µg/$268; 25 µg/$349
Select
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
18.1 kDa
5 µg/$268; 25 µg/$349
Select
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
16.6 kDa
5 µg/$268; 25 µg/$349
Viewing 1-25 of 50 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).