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GPR125 is an Orphan-B GPCR with an unknown ligand. GPR125, like GPR124, has a leucine rich repeat (LRR), an immunoglobulin (Ig) domain, and a hormone-binding domain (HBD). The Ig domain shows similarities to motilin and titin, while the LRR domain shows similarities to LRIG1 and SLIT1-2.
Gene Name: | G protein-coupled receptor 125 |
Family/Subfamily: | GPCR , Orphan-B |
Synonyms: | ADGRA3, GPR125, TEM5L, G protein-coupled receptor 125, PGR21 |
Target Sequences: | AY181243 AAO27355.1 Q8IWK6 |
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